无尿

Results The age,sex,the course of disease,the glycemia without meal and GHbA1c were closely related to the elderly type2diabetes patients.The urinary infection such as asymptomatic bacteriuria was common in clinic.The ma-jor flora detected was Gram megative bacillus.

结果 年龄、性别、糖尿病病程、空腹血糖及糖化血红蛋白与老年2型糖尿病合并泌尿系感染关系密切；泌尿系感染的临床类型以无症状性菌尿主，其菌群分布以G -杆菌为主。

Polyuria: frequent urination at the same time as each time more urine without the other's performance, first of all, attention should be paid to whether or not drinking too much, especially the children like sugar occur.

饮食性多尿：如尿频同时每次尿量多，而无其他表现时，首先要注意是否喝水太多，尤其是喜欢糖水的小儿多发生。

Results Compared with low-salt diet control group, the renal changes in CsA-L group were not obvious at the 2nd weeks, the urine volume and the level of BUN were remarkably increased in CsA-H group. At the 4th weeks, the urine volume was decreased; the levels of Crea and BUN were significantly increased and showed a significant positive correlation with the blood CsA concentration. Morphologic changes consisted of vacuolization of renal tubular cells, hyalinization of small arterioles and the light renal interstitial fibrosis.

结果 与低盐对照组相比，药后第2周CsA-L组各指标无明显变化，CsA-H组尿量增多，尿蛋白降低，尿素氮升高；药后第4周时，尿量呈减少趋势，肌酐和BUN明显升高，且与CsA血药浓度呈显著正相关，病理表现为肾小管细胞空泡变性及小动脉和肾间质病变，CsA-H组各种变化较CsA-L组更为明显。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

Further studies show that the main effect of Shenfu acupoint injection is to reduce patient's glomerulous urine protein, but not reduce tubulous urine protein (α1-M).

进一步研究显示穴位注射主要是降低患者的肾小球性蛋白尿(尿微量白蛋白、尿IgG)，对肾小管性蛋白尿(尿α1-M)无改善作用。

METHODS: Collaborative meta-analyses were undertaken of 194 unconfounded randomised trials of adjuvant chemotherapy or hormonal therapy that began by 1995. Many trials involved CMF (cyclophosphamide, methotrexate, fluorouracil), anthracycline-based combinations such as FAC (fluorouracil, doxorubicin, cyclophosphamide) or FEC (fluorouracil, epirubicin, cyclophosphamide), tamoxifen, or ovarian suppression: none involved taxanes, trastuzumab, raloxifene, or modern aromatase inhibitors.

对194个开始于1995年的关于辅助化疗或激素治疗的随机试验进行meta分析，许多试验包含了CMF(环磷酰胺、氨甲喋呤、氟尿嘧啶)，蒽环药物为基础的联合化疗比如FAC(氟尿嘧啶、阿霉素、环磷酰胺)或FEC（氟尿嘧啶、表阿霉素、环磷酰胺）及他莫昔芬或卵巢去势；无一包含紫杉烷类、赫赛汀、雷洛昔芬及芳香化酶抑制剂。

APHs, TF and GnH were tested in 93 patients with TBI,who were admitted to Zhejiang Provin-cial People's Hopital from March 2006 to June 2007. Patients with primary injury in the hypothalamic and pituitary regions, as detected by CT and/or MR/examination, as well as those with tumors or immune diseases in the CNS,endocrine or urinogenital systems, were excluded. The clinical data were analyzed according to Glasgow coma scores, type and degree of injury, and whether there was any secondary cerebral injury.

随机对浙江省人民医院2006年3月至2007年6月经系列头颅CT扫描和/或MRI检查，明确无下丘脑、垂体等部位的原发损伤，且既往无中枢神经系统、内分泌和泌尿生殖系统肿瘤及免疫性疾患史的93例门急诊和住院TBI患者的APHs、TF和GnH进行测定，并按患者的GCS评分、TBI类型和损伤程度以及有无继发性脑损害等因素进行分组研究，以同期20例健康体检者作为对照组。

Within natural disposition cortisol treats as the CYP3A4 active with 6 beta -hydroxycortisol in the urine proportion target; Within fresh metabolite 5-MDMT and bufotenine treat as the CYP2D6 active target in the urine proportion the research not to become Yang A mainly because LC/MS/MS to be unable to decide on in the urine 5-MDMT and 6 beta -hydroxycortisol..

以内生性cortisol与6β-hydroxycortisol在尿液中的比例当作CYP3A4活性的指标；以内生代谢物5-MDMT与bufotenine在尿液中的比例当作CYP2D6活性的指标的研究均未成功，主要因LC/MS/MS无法定出尿中5-MDMT及6β-hydroxycortisol。

Abstract］ objective to assess the efficacy and safety of transurethral resection of prostatewith plasmakinetic technique and to improve the qualities of pkrp.methods the data of 273 patients with benign prostatic hyperplasiawere retrospectively studied baseing on the mastering of pkrp.the average maximum urinary flow rate,the average residual urinary volumeand the average international prostate symptom score were analysed.results pkrp was successfully performed on 273 patients.intraoperative blood transfusion was performed in 6 cases,no obturator nerve reflex,transurethral resection syndrome,permanent urinary incontinence occurred and no death cases occurred.the follow-up time was 2～26 months with an average of 5.63 months,postoperative average qmax increased to 15.9 ml/s,and ruv decreased to 16.0 ml/s and the average ipss was 9.compared with those of preoperation,the differences were significant.conclusion pkrp has superior tissue cutting function and hemostasis.it is suggested that transurethral bipolar plasmakinetic resection of prostate be effective and safe.

目的 探讨经尿道双极等离子前列腺切除术的安全性与有效性，提高pkrp质量。方法回顾性分析273例良性前列腺增生患者pkrp资料，比较手术前后最大尿流率、膀胱剩余尿量及国际前列腺症状评分。结果 273例手术均顺利完成，术中输血6例，无闭孔神经反射、永久性尿失禁、经尿道电切综合征及死亡病例，随访2～26个月，平均5.63个月，qmax平均增至15.9 ml/s，ruv平均降至16.0 ml，ipss平均9分。与术前相比，各项指标均有明显改善。结论 pkrp具有良好的组织切割功能及可靠的止血作用，治疗bph安全有效。

In order to detect the concentration of the urine protein β_2-MG,ALb,IgG and THP.

表明2种温度贮存的尿标本，4种蛋白检测结果无显著差异。ALb、IgG和THP的测定值在随意尿和24h尿最有相关性，γ分别为0.7565，0.7845及0.7837。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。