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On the basis of the kinetic equation of substrate reaction in the presence of urea or guanidine hydrochloride, all microscopic kinetic constants for the free enzyme and enzyme-substrate binary and ternary complexes have been determined. The results of the present studies indicate that:①In the presence of urea or guanidine hydrochloride, enzyme-substrate complexes lose their activity less rapidly than the free enzyme. Therefore, both substrates, NADPH and 7, 8-dihydrofolate, protect dihydrofolate reductase against inactivation.②The denaturation of dihydrofolate reductase by urea follows single-phase kinetics, and changes in enzyme activity and tertiary structure proceed simultaneously in the unfolding process, so it may be an"all or none"process.③The GdnHCl-induced unfolding of the dihydrofolate shows a biphasic transition, while the change in the enzyme activity is a single exponential process. The rate constant of inactivation is consistent with that of the fast conformational change. Therefore, the kinetic intermediate of protein unfolding should be a partially folded and inactive form.

我们根据在脲或盐酸胍存在下的底物反应动力学方程求得游离酶和酶底物二元、三元复合物的微观动力学常数,结果表明:①酶-底物二元、三元复合物的失活速度明显慢于游离酶,说明两个底物二氢叶酸和NADPH对酶的失活都具有一定程度的保护作用;②在脲作用下,酶的失活和构象变化均为单指数项过程,而且酶的活力丧失和三级结构变化是同时发生的,说明二氢叶酸还原酶的脲变性可能是一个"全或无"的两态过程;③在盐酸胍作用下,酶的构象变化为两相过程,而失活则是单指数项过程,酶分子构象变化的快相速度常数与失活速度常数基本一致,因此我们认为二氢叶酸还原酶的盐酸胍变性过程中存在一个没有活力、但仍具备一定空间结构的变性中间体。

But the CRI and CSR index of coke, used at present, is measured under the atmosphere of no alkali. In the different conditions, alkaline or not, the results of the selective reaction of coke microstructure are different,especially sometimes just opposit...

有碱或无碱存在,对焦炭显微结构的选择性反应序列有时是相反的,并发现∑ISO具有比各向异性结构更强的高温抗碱侵蚀的能力,而前者主要来自气煤类煤,后者主要来自强粘结性煤,因此认为,为了增加焦炭中∑ISO的含量,适当降低对M40(M25)、M10的要求,以达到多用气煤类煤,并改善焦炭的实际质量是可行的。

The method of proctoclysis of Chinese traditional medicine is a new treatment way of combining clusis and TCM catharsis, by this means, Chinese traditional medicine can be absorbed promptly through rectal mucous membrane and entrance Greater circulation to treating total body or local disease. It has many advantages on treatment for diseases, such as convenient use, spreading easily, becoming effective rapidly and reliable effect, no bad response and ill effect, and so on.

中药直肠滴注法是中医学的&导法&与现代医学的灌肠法相结合而产生的一种新的给药方法,药物可通过直肠粘膜迅速吸收,进入大循环,发挥药效以治疗全身或局部疾病,具有方法简便、易于推广、应用范围广、见效快、疗效可靠、无明显不良反应和毒副作用等优点,该法用于脑出血急性期昏迷患者的抢救取得了好的疗效。

The results show that the zirconium sol has good spinnability when n: n= 1:3, reaction time is 6h and aging temperature is 15℃. The ZrO_2precursor fibers are made from hydrous zirconia chelated by acetylacetone. The sintercd fibers arecomposed of metastable tetragonal phase and sized about 15μm in diameter. Moreover, there aremany pores inside the fibers, but no cracks.4. ZrO_2/PVP hybrid fibers were prepared by blending the spinnable zirconium sol and 10 wt%PVP solution.

结果表明,当n(ZrOCl_2·8H_2O):n(H_2O_2)=1:3,反应时间6h,陈化温度15℃时可得纺丝性能良好的锆溶胶,ZrO_2前驱体连续纤维的组成主要为经乙酰丙酮配位的ZrO_2水合物,热处理后的ZrO_2纤维的相结构为亚稳四方相,纤维的直径为15μm左右,纤维中存在大量的纳米级气孔,但无明显裂纹。4。

The crystallization behavior of polyethylene terephthalate ; random poly (ethylene/tetramethylene terephthalate) P (ET/BT ; poly (ethylene terephthalate/ isophthalate) P (ET/EI and poly (ethylene terephthalate/adipate) P (ET/EA copolyesters; and block polyethylene terephthalate/polyethylene glycol and polyethylene terephthalate/polytetramethylene glycol were studied by DLI ; DSC; WAXD; PLM and IR technique.

中文题名PET及其共聚酯的结晶行为副题名外文题名 The crystallization behavior of PET and its copolyesters 论文作者边界导师封麟先叶胜荣教授学科专业高分子化学与物理研究领域\研究方向学位级别博士学位授予单位浙江大学学位授予日期2001 论文页码总数10,159页关键词聚对苯甲酸乙二酯聚酯结晶馆藏号BSLW /2003 /O633 /1 本文通过缩聚反应合成了不同分子量的聚对苯二甲酸乙二酯;聚对苯二甲酸酯P(ET/BT、聚(对苯二甲酸/间苯二甲酸)乙二醇酯P(ET/EI和聚乙二醇酯P(ET/EA等系列的无规共聚酯以及PET/PBG和PET/PEG等系列的嵌段共聚酯,并采用DLI、DSC、WAXD、IR和NMR等实验技术着重研究了它们的结晶行为与共聚酯的序列结构。

With increasing the concentration of the mixture of antimony oxide from 10 % to 20 %, the reaction time decreases from 90 min to about 30 min, but the optimized range of molar ratio of H3PO4 to antimony increases. The reaction temperature is not the main factor on particle size with the existence of H3PO4, the average particle size is c.a. 160nm without obviously variety in the temperature range from 60 °C to 90°C.

氧化锑混合物浓度从10%增加到20%时,反应达到平衡的时间从90min下降到30min左右,形成小粒径胶粒所需磷酸与锑摩尔比的最佳范围也随之上升;在稳定剂磷酸存在的条件下,温度不再是对胶体粒子粒径的主要影响因素,在60~90℃之间,形成的胶体五氧化二锑的粒径无明显变化,在160nm左右。

The toxicity to the liver were found in 27.8% and skin rashes appeared also in 27.8% of the patients. Eleven point one percent of the patients had different degrees of alopecia and toxicity of oculi, while the toxicity to the heart was only 2.78%.

结果27.8%的出现肝损害,2.78%的患者出现心脏毒性,11.1%的患者出现眼毒性,27.8%的患者出现皮肤过敏,69.4%的患者出现消化道反应,11.1%的患者有不同程度的脱发,36例患者均无肾功损害。

Eleven point one percent of the patients had different degrees of alopecia and toxicity of oculi, while the toxicity to the heart was only 2.78%. No toxicity to kindey appeared in all the patients involved.

结果27.8%的出现肝损害,2.78%的患者出现心脏毒性,11.1%的患者出现眼毒性,27.8%的患者出现皮肤过敏,69.4%的患者出现消化道反应,11.1%的患者有不同程度的脱发,36例患者均无肾功损害。

Results Reactions of digestive tract such as nausea and vomiting occurred in 69.4% of the patients. The toxicity to the liver were found in 27.8% and skin rashes appeared also in 27.8% of the patients. Eleven point one percent of the patients had different degrees of alopecia and toxicity of oculi, while the toxicity to the heart was only 2.78%.

结果27.8%的患者出现肝损害,2.78%的患者出现心脏毒性,11.1%的患者出现眼毒性,27.8%的患者出现皮肤过敏,69.4%的患者出现消化道反应,11.1%的患者有不同程度的脱发,36例患者均无肾功损害。

For ozonolysis, the SOA yield has not been changed by inorganic seed aerosol, because the products are mainly carboxylic acids, which has much lower saturation vapor pressure and thus easily undergo homogeneous nucleation or gas-particle partitioning to be in the aerosol phase.

而对于α-蒎烯臭氧氧化的过程,实验结果表明,干态硫酸铵颗粒物种子的存在对SOA产率无影响,对臭氧氧化生成的SOA分子鉴别的结果表明,可鉴别组分中有很高比例的有机羧酸类物质,这一比例远高于光氧化产物,这些有机酸具有较低的挥发性而极易形成颗粒相,并且不参与异相酸催化反应。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化,但却比去年同期高8%。

However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。