无危险的

To characterize the distribution of blood pressure, prevalence, and risk factors for hypertension in pediatric chronic kidney disease, we conducted a cross-sectional analysis of baseline BPs in 432 children (mean age 11 years; 60% male; mean glomerular filtration rate 44 mL/min per 1.73 m2) enrolled in the Chronic Kidney Disease in Children cohort study. BPs were obtained using an aneroid sphygmomanometer.

为了描绘血压的分布，流行和引儿童慢性肾功能不全引起的高血压的危险因子，我们对432名患有慢性肾功能不全的儿童的血压进行了一项有代表性的配伍研究（平均年龄为11岁，60%为男性，平均肾小球滤过率为44ml/min1.73m2）血压的测量是利用无水银血压计进行的，而肾小球滤过率则是根据碘海醇的清除率来测定。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In accordance with the provisions of the plan, by 2006, the city will be 3 years, 868 of the city's rural poor houseless families of persons with disabilities, families with severe dangerous, in the light of the city civil affairs departments to identify the rural poor housing standards for the construction of family housing; of 416 households of rural poor people with family adversity humble, to repair damaged housing transformation.

按照规定的计划，到2006年，这座城市将是3年， 868城市的农村贫困家庭的无房残疾人，家庭的严重危险，鉴于市民政部门确定的农村穷人的住房标准的家庭住房建设；对416户农村贫困人口家庭逆境谦卑，修复受损住房的转变。

The student may read Homer or AEschylus in the Greek without danger of dissipation or luxuriousness, for it implies that he in some measure emulate their heroes, and consecrate morning hours to their pages.

可以读荷马或埃斯库罗斯的希腊文原著的学生，决无放荡不羁或奢侈豪华的危险，因为他读了原著就会在相当程度之内仿效他们的英雄，会将他们的黎明奉献给他们的诗页。

It is, in fact, one of the most important tasks of psychic hygiene to pay continual attention to the symptomatology of unconscious contents and processes, for the good reason that the conscious mind is always in danger of becoming one-sided, of keeping to well-worn paths and getting stuck in blind alleys.

事实上，对无意识内容和过程的症状进行不间断的关注是心理卫生的最重要的任务之一，意识心灵总是有片面的危险，它遵循陈腐的路线，并且一个劲地钻死胡同。

Methods:a total of 50 patients of manic with agressive behavor and 50 patients with no agressive behavor were compaired with their rebation data.results: the two groups were signifcent different in brms and the dinical charaters.imply that the active,agression factor,dinical character of agressive history,irritably of brms were the agressive behavor danger factors.conclusions: to give nurse intervene and heath cducation in manic with agressive behavor early could decrease the agessive behavor mostly.

采用对照分析法，对50例有攻击行为的躁狂症患者和50例无攻击行为的躁狂症患者的相关资料进行分析和显著性检验。结果：两组躁狂症患者在brms和临床特征上存在显著差异，提示brms的动作活动、敌意因子分和临床特征中既往有攻击史，易激惹、不合作及医护人员的强制手段是躁狂症患者的攻击行为的危险因素。结论：及早对躁狂症攻击行为患者实施心理干预及健康指导，可以将攻击行为减少到最低限度。

Ying was abandoned by his parents when he was only weight 3 pound ; Zou was abandoned by his parents more than 50 days after he was born, he has serious heart problems, pulmonary hypertension and facing life-threatening; Snow is a child with cerebral palsy and has been abandoned; Zhao has serious equinus varus ; Lu leads to congenital absence of anus, this has not yet one month old baby was found in the trash can , and when he was sent to the orphanage he was dying; Run had been abandoned in a county hospital, only because she is a cleft lip and palate baby...

党英被父母遗弃时体重只有三斤多点，蔫蔫的；小邹成出生后被父母遗弃在山东省邹城县医院的过道上长达50多天，严重的心脏病致使他心内膜垫完全缺损、肺动脉高压，面临生命危险；瑞雪是脑瘫患儿，出生时由于硬肿症送到医院抢救，半岁后孩子出现脑瘫迹象，所以被遗弃；赵恒有严重的马蹄足内翻；路通先天无肛，这个还没有满月的娃是在路边的垃圾桶里被人发现的，送到福利院时已经奄奄一息；润润曾经被遗弃在河南一个县城医院里，只因为这是一个唇腭裂的宝宝。。。

Ying was abandoned byhis parents when he was only weight 3 pound ; Zou was abandoned byhis parents more than 50 days after he was born, he has serious heart problems, pulmonary hypertension and facing life-threatening; Snow is a child with cerebral palsy and has been abandoned; Zhao has serious equinus varus ; Lu leads to congenital absence of anus, this has not yet one month old baby was found in the trash can , and when he was sent to the orphanage he was dying; Run had been abandoned in a county hospital, only because she is a cleft lip and palate baby...

党英被父母遗弃时体重只有三斤多点，蔫蔫的；小邹成出生后被父母遗弃在山东省邹城县医院的过道上长达50多天，严重的心脏病致使他心内膜垫完全缺损、肺动脉高压，面临生命危险；瑞雪是脑瘫患儿，出生时由于硬肿症送到医院抢救，半岁后孩子出现脑瘫迹象，所以被遗弃；赵恒有严重的马蹄足内翻；路通先天无肛，这个还没有满月的娃是在路边的垃圾桶里被人发现的，送到福利院时已经奄奄一息；润润曾经被遗弃在河南一个县城医院里，只因为这是一个唇腭裂的宝宝。。。

27The danger grows that not only our trade will be discredited, but even that the temple of the great goddess Artemis will count for nothing. She whom Asia and all the world worships may soon be stripped of her renown.

27这不但使我们这分行业，有遭人唾弃的危险，而且连伟大女神阿尔特米的庙，也要被视为无物，甚至整个亚细亚和天下所敬拜的女神的尊威，也将被消灭。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。