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PPAR γ agonist displayed obvious renoprotective action,the mechanism was complicated, it could improve the metabolism of glucose ang lipid, depress blood preasure, protect small vessels endothelium,improve the system activity of blood clotting and fibronolysis, antiinflammation, otherwise the action was more obvious with the time passed, at the early stage the effective was better,so encourage the patients to take the medicine earily; when the patients with the mediate reanl function failure, Avandia did not display significantly renoprotective action, side reaction had no difference compared to the control group,was not necessary to regulate the dose of Avandia.But because of the sample size was small, we needed a biger sample to confirm the results. We confirmed that Prol2Ala had no difference in control case,diabetic nephropathy group and diabete group,In diabetic group and diabetic nephropathy group, Ala carriers compared to noncarrier all kinds of biochemical indicators were not different,Prol2Ala did not have association with diabete and diabetic nephropathy. But because of the sample size was small, weneeded a biger sample to confirm the results.

PPARγ激动剂对糖尿病肾病具有明显的保护作用，保护作用的机制是多方面的，除了改善糖脂代谢，降低血压外，还具有保护小血管内皮，改善凝血和纤溶系统活性，抗炎症等多方面的作用，且作用随着用药时间的延长而日趋明显，在疾病的早期应用效果更佳，故提倡早期用药；对伴有慢性肾功不全的患者，罗格列酮对肾脏靶器官的保护作用显现的并不明显，但副作用与对照组无明显差异，不用根据肾功情况调整用药，但由于样本量较小，上述结论尚需大样本进行进一步证实；本实验研究得出Prol2Ala变异在健康对照组、糖尿病组及糖尿病肾病组均无显著差异，糖尿病组及糖尿病肾病组临床各生化指标与Prol2Ala变异亦无相关性，Prol2Ala与糖尿病及糖尿病肾病不相关。

Ki-67 and Pgp expressions were measured by immunohistochemical analyses on multiple nonconsecutive sections from surgery or biopsy specimens of breast cancers.

结果：11位具有Ki-67表现乳癌病患，其肿瘤－背景比值明显高於13位无Ki-67表现者(4.26±0.41对2.25±0.33，P＜0.05)，然而8位具有P-醣蛋白表现及16位无P-醣蛋白表现，其肿瘤－背景比值则无明显差异(3.52±0.40对3.42±0.45，P＞0.05)。

Three hours OLV does not cause injury of the nondependent lung, yet six hours OLV leads to injury of the nondependent lung. Low-dose ALM would not deteriorate the injury of the nondependent lung.

OLV 3hr不会造成无通气肺组织的损伤，而OLV 6hr则引起无通气肺组织的损伤：小剂量ALM在提高HPV反应，改善OLV期间动脉氧合的同时，并不加重无通气肺组织的损伤。

Malondialdehyde production and total superoxide dismutase activity in samples of nondependent lung and dependent lung were detected and analysed in both groups on time of OLV 3hr and OLV 6hr to determine whether long-term OLV led to injury of the nondependent lung and whether the injury would be deteriorated by low-dose ALM.

通过对OLV 3hr及OLV 6hr时两组实验犬无通气肺与通气肺组织标本中丙二醛含量及总超氧化物歧化酶活力的测定，观察长时间OLV是否引起无通气肺组织损伤，并同时探讨小剂量ALM对无通气肺组织损伤的影响。

With manyadvantages, such as contactless, nonfriction, nonabrasion, nonlubrication,nonpollution, long life span, high precision, adjustable damp and stiffness,magnetic bearing has wide ranges in application.

此类轴承具有非接触、无摩擦、无磨损、无润滑、无污染、寿命长、精度高、刚度和阻尼可控、可调等一系列优点，应用前景十分广阔。

We also discussed the signal characteristics of each kind of tumors.MRI has ben showing great advantage in evaluating the tumors of the spinal canal:nonionizing radiation. noninvasive, no bony artifacts, multiple planes imaging, there is no need to inject agents to the canal, and one image can demonstrate multiple lesions.

MRI在评价椎管肿瘤方面显示出世大的优越性：无电离辐射、无创伤性、无骨伪影、多平面成像、不需椎管内注入造影剂、多发病变一次成像，直接显示肿瘤信号及其与周围结构的关系，定位及定性准确率高。

Objective To obtain information on the application value of percutaneous epididymal sperm aspiration and percutaneous testicle sperm aspiration in the differentiating diagnosis of obstructive and nonobstructive azoospermia.

目的探讨经皮附睾精子抽吸术及经皮睾丸精子抽吸术在无精子症鉴别诊断中的应用价值。方法采用PESA或PTSA对梗阻性无精子症组37例及非梗阻性无精子症组28例进行附睾或睾丸取精，细胞学涂片进行分析。

The expression of subunits α5,β1,β3 was detected in normal morulas and increased in blastocysts. The expression of subunit α1 was not detected in morulas or blastocysts, but detected only in outgrowing trophocytes. 3. Expression of integrin β3 in irradiated group embryos was weaker than that of normal group. There was no expression of integrin α1 both in morulas and blastocysts in irradiated group and no difference in the expression of subunits α5 and β1 between these two groups.

结果：1、超声波照射组胚胎贴附率、滋养细胞外延生长率均显著低于正常胚胎。2、正常胚胎桑椹胚期即有α5、β1、β3整合素表达，而无α1表达；囊胚期α5、β1、β3表达增强，仍无α1表达；α1只出现在外延生长的滋养细胞。3、超声波照射组胚胎β3整合素的表达明显弱于正常组，且未见α1表达；而α5、β1的表达两组间无差异。

Methamidophos affected the mean ratio of ovigerous to non-ovigerous females and the mean mictic rate significantly but had less effect on the total resting egg production, while 17β-estradiol was in adverse.

甲胺磷和17β-雌二醇对实验期间轮虫的平均种群增长率均有显著影响，但对轮虫种群中的混交雌体受精率的平均值无显著影响；甲胺磷对实验期间轮虫种群中的携卵雌体数／非携卵雌体数和混交雌体百分率的平均值均有显著影响，而17β-雌二醇则无显著影响；甲胺磷对实验期间轮虫的休眠卵总产量无显著影响，而17β-雌二醇的影响较显著。

Res ults:Before IST colonies of CFU-F from only 5 patients were normal,and the colo nies of CFU-F in decreased severely or even absent for the rest;the response ra te of AA patients with CFU-F formation was higher than that of those without CF U-F Formation but not significantly;after IST colonies of CFU-F in creased in significantly from those patients achiveve complete remission and parial remissi on Also they no significant as compared with nonresponsive patients.

结果：IST前仅5例患者CFU-F数量正常，余75例患者CFU-F生长严重缺陷或无生长；有CFU-F生长者疗效优于无CFU-F生长者，但差异无显著性(P＞0.05)。IST后获基本治愈者骨髓CFU-F数量增加最为显著(P＜0.01 )，缓解者及明显进步者CFU-F数量亦增加，但差异不显著(P＞0.05)。

And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时，论述了一体化管理体系构建中的几个主要问题，包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。