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These results suggest that the activate spleen-energy method can achieve appetitive purpose by not only affecting the gastrointestinal tract function in periphery, but also regulating the process of ingestion in brain. The basic research about ingestion indicate: one hand, after food enters the gastro-intestinal tract, the endocrine cell of the intestinal tract is activated and secrete many kinds of brains intestines peptide, the level of the brain intestines peptide in blood as the periphery signal spreads to the central nervous system regions that control digest and feeding behavior. On the other hand, it has been shown that dorsal parabranchial neurons, containing CCK-8S, extend fibers to the VMH and are involved in the inhibition of feeding .

关于摄食控制的基础研究表明,一方面食物进入胃肠道后,激活肠道的内分泌细胞,分泌多种脑肠肽如CCK-8S,这些脑肠肽在血中的水平作为外周信号可通过"肠—脑轴"传入中枢神经系统介导消化和摄食行为的部位,影响摄食中枢神经元的活动调节动物的摄食行为;另一方面中枢神经元可合成释放内源性的神经肽直接作用于摄食中枢神经元调节摄食,如中枢鳃旁体神经元的神经纤维就可延伸到达VMH,并且合成释放内源性的CCK-8S。

The result showed that IFN-γ was distributed over 20 nucleus of the hypothalamus, such as nucleus mamillaris medialis, nucleus pre-opticus medialis, area anterior hypothalami, nucleus ventromedialis, nucleus reunions, nucleus paraventricularis, nucleus supra optic, and etc. Many of IFN-γ positive nerve fibers were found in supra optic nucleus, paraventricular nucleus, nucleus mamillaris medialis and etc. Nerve fibers and astrocytes IFN-γ immunoreactive positive cells spreaded in paraventricular nucleus, nucleus pre-opticus lateralis, nucleus pre-opticus medialis and etc. At the same time, IFN-γ is also observed obviously in adenohypophysis and neurohypophysis. IFN-γ also expresses in follicular and corpus luteum.

结果显示,IFN-γ分布于乳头体内侧核、视前内侧核、下丘脑前区、腹内侧核、连接核、室旁核、视上核等20个核团中,各部分核团细胞着色程度深浅不一;在视上核、室旁核分泌部乳头体内侧核等有大量的阳性神经纤维;同时在室周核、视前外侧核、视前内侧核等13个核团中散布有一些阳性星形胶质细胞,与阳性神经细胞交错共存;腺垂体中腺细胞和神经垂体中神经纤维均有IFN-γ表达;卵泡和黄体中也有IFN-γ存在。

Neuronal cell bodies and fibers with moderate mGluR7-LI were seen in the olfactory bulb,anterior olfactory nucleus,piriform cortex,septofimbrial nucleus,bed nucleus of the strial terminalis,lateral hypothalamic area,paraventricular hypothalamic nucleus,supramammillary nucleus,medial and lateral mammillary nuclei,most part of the thalamus,medial and lateral geniculate bodies,nucleus of the optic tract,red nucleus,substantia nigra,interpeduncular nucleus,pontine nuclei,lateral parabrachial nucleus,superior olivary complex,nucleus of the trapezoid body,motor nucleus of the trigeminal nerve,facial nucleus,ambiguus nucleus,cochlear nucleus,vestibular nuclei,nucleus of the solitary tract,hypoglossal nucleus,prepositus hypoglossal nucleus,medullary reticular formation,Purkinje cells of the cerebellum,nucleus raphe obscurus,intermediolateral nucleus of the spinal cord,Onuf′s nucleus and lamina X of the spinal cord.

呈中等强度染色的神经元胞体和纤维见于嗅结节、前嗅核、梨状皮质、隔伞核、终纹床核、下丘脑外侧区、下丘脑室旁核、乳头体上核、乳头体内、外核、丘脑大部分核团、内外侧膝状体、视束核、红核、黑质、脚间核、桥核、臂旁外侧核、上橄榄复合体、斜方体核、三叉神经运动核、面神经核、疑核、耳蜗核、前庭核簇、楔束外核、孤束核、舌下神经核、舌下神经前置核、中缝隐核、延髓网状结构、小脑蒲肯野细胞层、脊髓中间带外侧核、Onuf核和中央管周围灰质。

Results (1) Osteitis and destruction of end-plate showed long T1 and long T2.(2) Anterior and lateral abscess had long T1 and long T2 presenting even and structure-less signal.(3) The intervertebral discs showed normal or only degeneration at the early stage, and destroyed at later stage.(4) With Gd-DTPA enhancement, fibrotic granulation around abscess and destroyed area was well demonstrated.(5) Abscess in the bone and/or paraspinal abscess, destruction of end-plate were the important evidence for early diagnosis.

结果 (1)椎体骨炎及终板破坏呈长T1长T2信号,(2)椎旁或椎前冷脓肿呈长T1长T2均匀无结构信号,且上下跨越范围较大,(3)早期椎间盘信号正常或只出现退变,晚期则被破坏,(4)Gd-DTPA增强扫描可清楚显示冷脓肿周围纤维肉芽组织及椎管内侵犯,(5)骨内小脓肿和/或椎旁脓肿、椎体终板破坏是MRI诊断早期脊柱结核的重要依据。

At interphase, there is no cytoplasmic channel in the cell walls of PMCs; At zygonema and pachynema, a lot of cytoplasmic channel, ranging in diameter from 150nm to 600nm, appears; After pachynema, the number of channels decrease rapidly.

在间期的花粉母细胞间未见胞质通道,胞质通道在偶线期前后形成并开放,在粗线期以后迅速减少。在细线期和偶线期,花粉母细胞细胞质膜与细胞壁之间的质外体出现大量的小泡,即所谓的壁旁体

PRL-LIR positive perikarya were mainly seen in nucleus suprachiasmaticus, nucleus paraventricularis preopticus, nucleus supraopticus, nucleus hypothalamus paraventricularis, nucleus periventricularis arcuatus and nucleus accumbens. PRL-LIR fibers and their terminals were detected in paleostriatum and median eminence.

结果,PRL阳性胞体主要分布在视交叉上核、视前室旁核、视上核、下丘脑室旁核、弓状核和伏隔核,旧纹状体、正中隆起存在大量阳性纤维末梢,在侧脑室腹侧的室管膜和脑基底神经胶质板上也存在PRL阳性神经元。

These results suggest that the activate spleen-energy method can achieve appetitive purpose by not only affecting the gastrointestinal tract function in periphery, but also regulating the process of ingestion in brain. The basic research about ingestion indicate: one hand, after food enters the gastro-intestinal tract, the endocrine cell of the intestinal tract is activated and secrete many kinds of brains intestines peptide, the level of the brain intestines peptide in blood as the periphery signal spreads to the central nervous system regions that control digest and feeding behavior. On the other hand, it has been shown that dorsal parabranchial neurons, containing CCK-8S, extend fibers to the VMH and are involved in the inhibition of feeding .

关于摄食控制的基础研究表明,一方面食物进入胃肠道后,激活肠道的内分泌细胞,分泌多种脑肠肽如CCK-8S,这些脑肠肽在血中的水平作为外周信号可通过&肠—脑轴&传入中枢神经系统介导消化和摄食行为的部位,影响摄食中枢神经元的活动调节动物的摄食行为;另一方面中枢神经元可合成释放内源性的神经肽直接作用于摄食中枢神经元调节摄食,如中枢鳃旁体神经元的神经纤维就可延伸到达VMH,并且合成释放内源性的CCK-8S。

There is a polarized organelle, Golgi complex consisted of several saccules and some vesicles beside the nucleus and there are some osmiophilic bodies beneath the parasite pellicule.

结果表明,配子体是一渐进发育的单核、惰性虫体,其核旁有一个由扁平囊和泡状小体极性排列组成的细胞器———高尔基体,虫体被膜下有嗜锇小体。

Results Irregular symmetrical sheets of lesions with low density around bilateral ventricles were seen in all patients and 62 cases around the front horns, 53 cases retral horns and 38 cases beside the ventricles.

结果 :72例患者 CT平扫均见双侧侧脑室前后角及体部旁或半卵圆中心区脑白质大小不等斑片状不规则的大致对称的低密度影,发生在侧脑室前角周围 6 2例,后角周围 5 3例,侧脑室体旁 38例,半卵圆区 19例,伴有腔隙性脑梗死 4 1例。

When aborted rats were injected with 10 IU/g IFN-γin group D, compared with group A, expression of TNF-αinmmuopositive substance in the nucleus pre-opticus medialis, nucleus supra-opticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, nucleus arcuatus hypothalami were highly increased, conversely, the ones in the nucleus pre-opticus suprachiasmaticus, neurohypophsis, adenohypophysis, ovary were obviously decreased, the change in the uterus was not remarkable; Compared with group B, expression of TNF-αin the arcuatus hypothalami was obviously enhanced, while in the nucleus pre-opticus suprachiasmaticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, nucleus ventromedialis hypothalami, nucleus dorsomedialis hypothalami, neurohypophsis, pars intermedia, ovary, the results were on the contrary, the uterus had no significantly variation; Compared with group C, expression of TNF-αin the nucleus pre-opticus medialis, nucleus supra-opticus, nucleus paraventricularis hypothalami, nucleus arcuatus hypothalami, adenohypophysis and pars intermedia had an obviously risen trend, however, the variation in the nucleus pre-opticus suprachiasmaticus, nucleus periventricularis hypothalami, neurohypophsis, pars intermedia, follicle and corpus luteum was completely opposite, uterus had no obviously change.

外源腹腔注射10 IU/g IFN-γ后,同A组相比:D组TNF-α免疫阳性产物在下丘脑视前内侧核、视上核、视前大细胞核、室周核、室旁核、弓状核显著增高,在视交叉上核显著降低,在其它核团较A组无显著差异,在神经垂体、垂体前叶、卵巢中阳性产物表达均较A组显著降低,在子宫中的表达较A组变化不明显;同B组相比:D组TNF-α免疫阳性产物在弓状核显著增高,在视交叉上核、视前大细胞核、室周核、室旁核、腹内侧核、背内侧核、神经垂体、垂体中间部、卵巢各部阳性物质表达均显著降低,在子宫表达变化不显著;同C组相比:D组下丘脑视前内侧核、视上核、室旁核、弓状核、垂体前叶与中间部均显著增高,在视交叉上核、室周核、神经垂体、卵泡、黄体中均显著降低,子宫中表达变化不明显。

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I will endeavour to find you some assistance.

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