新类型

Based on the QSAR equation for MDR modulators, a new type of MDR modulators was designed with benzimidazole moiety as their parent nucleus, and four compounds of this type were synthesized and characterized.

在MDR逆转剂构效关系的理论指导下，选定苯并咪唑为母核，设计了一类新的MDR逆转剂候选化合物，合成了4个这种类型的新化合物。

Among those hydrogenbonding residues, Tyr119, His227, Asn392 and Leu451 could form hydrogen bond with the benzofuran inhibitots and Tyrl07, Asn175, Thr211 and Asp412 were newly discovered hydrogen-bonding residues, which were highly conserved residues across the NMT family and would play an important role in the design of NMT inhibitots with novel chemical scaffold.

CaNMT活性位点发现有两个氧键作用区域，其中Tyrll9，His227，Asn392和Leu451是与已有抑制剂的氢键结合位点，Tyr107，Asn175，Thr211和Asp412是新发现的氢键结合位点，而且在NMT家族中高度稳定，它们对设计新结构类型的CaNMT抑制剂具有重要作用。

To assess a broad spectrum of problems and opportunities for mixed-use, BOMA(Building Owners and Managers Association International), ICSC (International Council of Shopping Centers), NAIOP (National Association of Industrial and Office Properties) and the NMHC developed a ross organizational membership survey. The results of this landmark co-sponsored survey—which established a new working definition for mixed use—are discussed along with some background on the history of this product type—which today accounts for about 20% of all new space built in the United States.

为了评价混合用途开发普遍存在的问题和机遇国际建筑业主和经理协会、国际购物中心协会（ICSC、全国工业及写字楼物业协会和全国多元房屋协会人员交叉组织的调查，在这次具有里程碑意义的共同发起的调查结果，是随同讨论这个产品类型的一些历史背景，为混合用途确立了一个新的工作定义，今天在美国所有新的建筑空间中就占了约20 %。

Compared with the initial value problems of scalar conservation laws with smooth flux function, the global weak entropy solutions for the initial-boundary value problems of scalar conservation laws with weak discontinuous flux function include the following new interaction types: a rarefaction wave collides with the boundary and is absorbed compltetely or partially by the boundary; a rarefaction wave collides with the boundary and the boundary will reflect a contact or non-contact shock wave; a contact or non-contact shock wave collides with the boundary and is absorbed by the boundary; a contact or non-contact shock wave collides with the boundary and a new non-contact shock will rebound from the boundary simultaneously or later.

与具有光滑流函数的单个守恒律的初始值问题相比，具有弱间断流函数的单个守恒律初边值问题的整体弱熵解中包括下列新的相互作用类型：稀疏波碰到边界并被边界部分或全部吸收；稀疏波与边界相撞，边界反射出一个接触或非接触激波；接触或非接触激波碰到边界并被边界吸收；接触或非接触激波与边界相撞，边界同时或稍后反射出一个新的非接触激波。

ResultsEffective rate of chemotherapy was 86.6% which was associated with clinical stage and histology. Eight-four patients received radical hysterectomy. The histological grade of 17 patients was lowered, lymph nodes in 19 patients were positive, and 6 patients had parametrium invasion. One patient died within 1 year after the operation, and 5 patients recurred.

结果：新辅助化疗的近期有效率为86.6%；与疗效有关的因素为临床分期和病理类型；新辅助化疗后84例患者可以手术，术后病理降级的有17例，术后淋巴结阳性者19例，宫旁浸润者6例；随访中1例患者术后1年内死亡，5例复发，余患者均健在。

Ren Yuxin expresses, annual game industry is growing ceaselessly, total meeting has new game type, new trend to be in arisen, and 2008, the game of fistfight element predicts to be able to be popular in home.

任宇昕表示，每年游戏行业在不断发展，总会有新的游戏类型、新的潮流在兴起，而2008年，格斗元素的游戏预计会在国内大行其道。

This paper found that this main paradigms ignored the restructuring of global space and new spatial division of industry, from many reviews of the empirical researches, and failed to explain how the china urbanization do emerge and how its mechanism do trigger? With review of the globalist opinions, then, this paper tried to support the new research of urban region, including region-state model and metropolitanhind land system.

本文透过文献的评析发现，这类型的研究缺乏一个以全球空间的表述方式和新的产业分工来支持和说明中国都市化形成的机制和作用力，其次则透过部分全球主义学者的论述来支持新的研究范型，这包括区域国家和都会区－腹地系统二个空间模式。

The formation of the gold deposit is discussed from various aspects such as the nature of mineralizing source rocks the gold-bearing ultrabasic r...

超基性岩蚀变热液型金矿床，在岩金矿床中是新的类型，在矿床成因学上是新的概念。

The mutation R778L is the most common mutation of ATP7B gene in Chinese WD patients.

经检索2790del3是ATP7B基因新突变类型。R778L是中国人最常见的突变类型。

However, it can only implement the limited operation to the spatial objects, cannot carry on transformation, index, interlink age and excavation to the spatial data, and hard integrate other information with combining map variable to set up and analysis new variable. Meanwhile, relational model in the traditional DBMS and the object- oriented modeling do not completely suit the spatial application domain. The relational model can handle topological relation well, but shows inabilities to that complicated level crossing the spatial region. Object-oriented model using software method based on the principle of the customer defined data type supports the abstract data type, especially spatial abstract data type, and possesses polymorphism and inheritances, and it can deal with topological and the layer relation, but hardly processes important continuous phenomenon in space.

GIS是当今操作有关空间信息的成熟工具和技术，但其只能对空间对象进行有限的操作，不能对空间数据进行变换、索引、链接和挖掘，难以集成其他信息来构建和分析新变量；而传统数据库管理模型中的关系模型和面向对象建模也不完全适合空间应用这一领域，关系模型能够较好地处理拓扑关系，但对表示横跨空间区域的复杂层次却无能为力；面向对象模型的软件方法支持抽象数据类型，特别是空间抽象数据类型，具有继承性和多态性，能够处理拓扑和层次关系，但难以处理空间中重要的连续性现象。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了