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Doxy treatment significantly reduced intimal SMCs proliferation from 62.76%±1.02% in the controls to 43.23%±1.06% at 7 days after injury (P.01). CONCLUSION: Doxy treatment inhibits the activity of MMPs, the SMCs proliferation of intimal, neointimal hyperplasia and vascular remodeling, suggesting that Doxy treatment is useful in preventing restenosis after PTCA.

强力霉素可以显著降低血管损伤后MMPs活性,抑制内膜平滑肌细胞的增殖、新生内膜增生以及管腔重构,提示它可能具有防治PTCA术后再狭窄的作用。

Objective: The purposes of the present study are as follows: 1 To study the effect of direct contact with VSMC on transdifferentiation of MSC; 2 To construct MSC of Dual-stable expression of AT2R gene medicated by tetracycline regulatable system.; 3 To investigate the effects of AT2R gene medicated by tetracycline regulatable system on neointimal hyperplasia in rat carotid arteries after balloon angioplasty.

本实验体外观察MSC与VSMC在直接接触培养下的分化情况,并以MSC为载体,通过体外细胞基因转染及筛选,获得双重稳定受到强力霉素调控表达AT2R基因的MSC,将此受到调控表达的AT2R基因导入大鼠颈动脉球囊损伤动物模型中,观察MSC细胞移植实现AT2R基因在体可调控表达在新生内膜中形成的作用及潜在意义。

The co-eluting stent, sirolimus-eluting stent and bare-metal stent were implanted into porcine coronary artery model of sac expansion; 28 days later, the neointirnal area, mean neointimal thickness and reendothelialization of the stented coronary arteries were analyzed.

在猪冠状动脉球囊扩张模型中,植入雷帕霉素/雌二醇复合洗脱支架、雷帕霉素洗脱支架和裸支架,术后28 d考察支架血管段新生内膜面积、内膜平均厚度及支架内皮化程度。

DNA gyrase ; Novobiocin ; Antituberculosis agents ; Screening model

DNA回旋酶;新生霉素;抗结核药物;筛选模型

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。