新生物

The courses in this academic program are political theory, foreign languages, applied computational technology, experimental biology, microbiology, molecular biology, genetic engineering, bioseparation engineering, bioreaction engineering, chemical thermodynamics, mass transfer, chemical process simulation, pharmacology, preparation of finished traditional Chinese medicines, pharmaceutical chemistry, GMP in pharmaceutical industry, liquid-to-liquid extraction, pharmaceutical properties measurement and quality control, pharmacy administration, etc.

其工程硕士学位授权单位培养从事生物制药、合成制药、中药开发、药剂、药物性能检测与分析的高级工程技术人才。研修的主要课程有：政治理论课、外语课、数值分析、计算机应用技术、现代生物学与技术实验、现代微生物学、分子生物学、基因工程、生物分离工程、生物反应工程、化工热力学、化工传递过程原理、化工过程模拟、药理学新进展、中成药的制备、药物化学的进展、制药工业的GMP、液液萃取基础、药品性能检测与质量控制、药业管理学等。

Preliminary antitumor activity in vitro of the new compounds indicated that the compounds have obvious inhibitory effect on human leukaemia cell (HL-60) and human galactophore cancer cell (MDA-MB-468) in the concentration of 10-4 mol/L. This result is a basis for further study on the synthesis and biological activity of this kind of compounds.

对所合成的10个新化合物进行了抗肿瘤体外生物活性试验，初步生物活性实验结果表明，该类化合物在浓度为10-4 mol/L时对人白血病细胞株(HL-60)和人乳腺癌细胞株(MDA-MB-468)有明显的抑制作用，在浓度为10-5 mol/L时没有明显的抑制作用，这一研究结果为进一步研究此类化合物的合成、生物活性的研究奠定了基础。

In this paper, turf peat, straw, wheat bran, Marc, bagasse as raw materials for bio-solid fermentation, culture feed yeast and mycoprotein, while humic acid associated biochemical and biological activity of enzymes is an ideal feed attitive of multi-enzyme protein feed, that provides a new resources of bio-protein feed for our country's livestock breeding and production of green food.

本文以草炭、秸秆、麸皮、果渣、蔗渣和酒糟等为原料的生物固体发酵，培养饲料酵母及菌体蛋白，同时伴生的生化腐植酸和生物活性酶是一种较理想的畜用多酶蛋白饲料添加剂，为我国畜牧生态养殖和绿色食品生产提供了新的生物蛋白饲料资源。

To establish new methods for highly sensitive time-resolved fluorescence bioassay, several new lanthanide fluorescence complexes were synthesized and used for the preparations of nanometer-sized lanthanide fluorescence biolabels. Novel lanthanide fluorescence nano-biolabels are uniform (25-55 nm in diameters),strongly fluorescent with long fluorescence lifetime, highly photostable and biocompatible.

本项目以时间分辨荧光生物分析新方法的建立与应用为研究目的，在合成出几种稀土荧光配合物的基础上，建立了几种新型强荧光性纳米稀土荧光生物标记材料的可控制备方法，生物标记方法及其在时间分辨荧光免疫分析中的应用方法。

To establish new methods for highly sensitive time-resolved fluorescence bioassay, several new lanthanide fluorescence complexes were synthesized and used for the preparations of nanometer-sized lanthanide fluorescence biolabels. Novel lanthanide fluorescence nano-biolabels are uniform (25-55 nm in diameters),strongly fluorescent with long fluorescence lifetime, highly photostable and biocompatible.

中文摘要：本项目以时间分辨荧光生物分析新方法的建立与应用为研究目的，在合成出几种稀土荧光配合物的基础上，建立了几种新型强荧光性纳米稀土荧光生物标记材料的可控制备方法，生物标记方法及其在时间分辨荧光免疫分析中的应用方法。

Catalytic techniques for deep desulfurization, denitrogenation and dearomatization in production of clean gasoline and diesel fuels were reviewed, especially those for producing low-sulfur and extra-low-sulfur gasoline and diesel oil, among which technologies arousing most attention are sulfur-reducing FCC catalyst and additives, selective hydrogenation catalysts and technology, adsorptive desul-f urization of gasoline and diesel oil, biologically catalytic desulf urization of diesel oil, and selective oxid...

为面对新世纪清洁燃料生产的新机遇和新挑战，各种生产清洁燃料的催化技术正在竞相开发之中，尤其是生产低硫、超低硫汽油与柴油技术。其中，催化裂化降硫催化剂和助剂、选择性加氢处理新催化剂及工艺、汽柴油吸附脱硫、柴油生物催化脱硫和选择性氧化脱硫等新技术尤其引人注目。我国应加快清洁燃料生产催化新技术的开发研究，为生产更清洁的汽油和柴油燃料提供技术储备。

Thinking of presenting problems, this research mainly studied some solid base catalysts which own higher catalysis ability and longer lifetime. Then, the phase diagram and equilibrium data of oil-alcohol-biodiesel-glycerol multiphase system were measured because the biodiesel producing process lacks of thermodynamic data.Based on a double-membranes theory and the thermodynamic data, a kinetic model was proposed. In addition, a mult-step extraction process was proposed to dispose the jatropha curcas l oil with high acid value in order to decrease the acid value. Then, a new technology of biodiesel producing using solid base as a catalyst was developed. The study objects and results are as follows.

本研究针对负载型固体碱催化剂活性组分易流失、使用寿命短的缺点，制备了高效、稳定的固体碱催化剂；针对生物柴油制备体系热力学数据缺乏的问题，测定了大豆油-醇-生物柴油-甘油体系的相图和平衡特性，在此基础上基于双膜理论，建立了固体碱制备生物柴油的动力学模型；同时针对酸价较高的麻疯果油，提出了先用甲醇或乙醇多级萃取降低酸价，再用固体碱催化制备的新工艺。

The production process of biological briquettes was proposed in the paper with a comparison study of common briquettes and biological briquettes.

研究出生物型煤的生产工艺流程，对型煤和生物型煤的固硫技术进行了研究，成功试验生产出固硫性能优良的生物型煤，为中国煤能源可持续发展利用开辟了新途径。

The journal publishes original and significant contributions on the systematics and phylogeny of invertebrates worldwide, including papers on defined taxonomic groups and on the phylogeny, biogeography and/or other aspects of biodiversity and general biology of the group; contributions on the systematics of selected species; short, general papers, pertinent to invertebrate systematic biology on methodology, theoretical systematics, cladistics, phylogeny, molecular biology and biogeography; reviews of general invertebrate systematics, containing innovative data or overviews of current theories.

杂志刊载世界范围内的无脊椎动物的系统分类学和系统发育的原始和重要投稿，包括关于精确分类种群和种群生物多样性与普通生物学的系统发育，生物地理和/或其它方面的论文；关于选择物种系统分类学的投稿；有关无脊椎动物系统生物学的方法学，理论系统分类学，遗传分类学，系统发育，分子生物学和生物地理的短概括性论文；无脊椎动物普通系统分类学的评论，包括新数据或当前理论的观点。

The possibility of researching gene mutation with the technique of gene chip was discussed. A new imagination to randomly determine DNA sequence in different living beings with the technique of gene chip was advanced. In this way, whether the encoding sequence gene in DNA of eukaryon organism has some regularity was studied.

进而提出新设想——采用基因芯片技术对不同生物群体随机抽样进行DNA测序，从而探讨在真核生物DNA分子链上编码序列遗传基因的变化是否有规则而非随机的，非编码序列遗传基因是否为生物进化过程中曾经有表达能力的结构基因，并分析可能获得的结果。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。