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新生儿窒息

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Objective: To explore the dynamic changes of protein C, Protein S and antithrombin Ⅲ in asphyctic neonates.

目的:探讨窒息缺氧对新生儿血浆蛋白C、S、抗凝血酶Ⅲ活性的影响。

Objective: To study the Neonatal Behavioral neurological Assessment on the clinical significance in apneic newborns.

目的:探讨新生儿行为神经测定对足月窒息新生儿评定的临床意义。

Results: The scores of NBNA were all drop in apneic newborns and were lower when apnea was more seriously.

结果:NBNA评分在窒息新生儿中均下降,并与窒息程度呈相关。

Methods Eighty asphyxial neonates were divided into routine group(55 cases)and intervention group(25 cases).

方法将80例窒息新生儿分为常规组55例和干预组25例。20例非窒息儿为对照组。

Methods Eighty asphyxial neonates were divided into routine group (55 cases) and intervention group (25 eases). Twenty neonates who weren't asphyxial were set as a control group.

将80例窒息新生儿分为常规组55例和干预组25例。20例非窒息儿为对照组。

Methods The blood flow parameters of superior mesentric artery and coelia artery in 22 asphyxiated neonates and 30 healthy full-term infants were measured on the first day, the third day and the seventh day of life by using colour Doppler sonography.

应用多普勒超声血流显像技术,对22例(30例次)窒息后新生儿于生后1、3、7天进行了肠系膜上动脉和腹腔动脉的血流各参数测定,并以30例正常足月新生儿作为对照。

Risk factors of mortality by univariate analysis were: outborn babies, resuscitation before admission, first born baby, low pH, high oxygen index, high alveolar- arterial oxygen tension gradient (AaDO2) at admission, high Of and AaDO2 at 2 hours after admission, shock, pneumothorax, asphyxia, pulmonary hemorrhage, persistent pulmonary hypertension of newborn, and renal failure. Logistic regression analysis showed asphyxia, pneumothorax and PPHN are the most important risk factors of mortality in MAS. How to diminish these events is the key point for reducing the mortality rate of MAS.

又变项分析显示,死亡危险因子包括院外出生婴儿,黑心诊时需急救,第一胎,刚入院时的Ph、OI、AaDO2,住院后2小时的OI、AaDO2,休克、气胸、室息、肺出血、新生儿肺动脉高压;回归分析则显示窒息,气胸及新生儿肺动脉高压是死亡的危险因子,如何减少这些事故,将是降低便吸入症候群死亡的重要因素。

Coagulation dysfunction does exist in neonates with pneumorrhagia caused by scleredema and asphyxia. Plasma TXB2 and FPA should be considered as the early objective monitoring indices in neonates who are highly suspected as having pneumorrhagia . Lung diseases Infant, newborn Thromboxane B2 Fibrinopeptides A Hemorhage

新生儿肺出血患儿存在血小板活化和异常凝血;窒息和硬肿症所致的新生儿肺出血都存在止血凝血功能障碍这一共同因素;TXB2和FPA可作为预测新生儿肺出血的早期客观监测指标。

ConclusionsCoagulation dysfunction does exist in neonates with pneumorrhagia caused by scleredema and asphyxia. Plasma TXB2 and FPA should be considered as the early objective monitoring indices in neonates who are highly suspected as having pneumorrhagia.Key wordsLung diseasesInfant, newbornThromboxane B2Fibrinopeptides AHemorhage

结论新生儿肺出血患儿存在血小板活化和异常凝血;窒息和硬肿症所致的新生儿肺出血都存在止血凝血功能障碍这一共同因素;TXB2和FPA可作为预测新生儿肺出血的早期客观监测指标。

Methods The asphyxiated neonates were randomly divided into two groups. Neonates in control group were cured by conventional therapy, and in adenosine group were cured by adenosine at the same time.

60例窒息新生儿随机分为治疗对照组和腺苷治疗组,均予常规治疗,腺苷治疗组同时予腺苷治疗,分别在1、7 d测定各组新生儿血清心肌酶水平。

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