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The purified immunoglobulins were effective in the inhibition of endothelial cell adhesion, proliferation and angiogenesis in chick chorioallantoic membrane in vitro, and in anti-tumor activity by the adoptive transfer in vivo.

将该抗体纯化后,纯化的免疫球蛋白可以有效地抑制体外内皮细胞的粘附、增殖和鸡胚绒毛尿囊膜的新生血管形成,体内过继输入治疗亦可引起抗瘤效果。

Chorioretinal eaxminations of pathologic myopia show complicated features, and the multiple CNV causes severe damage to the visual function. FFA can provide the evidences for the clinical intervention.

病理性 近视视网膜脉络膜呈现复杂多样的病变特征,尤其是脉络膜新生血管多发危害大,FFA为临床干预治疗提供依据。

Althought this surgery has been reported by a few doctors recently, the safety and effectiveness need to be evaluated in further studies. In our study, the approach of the chorioretinal venous anatomosis in the model eyes with branch retinal vein occlusion, are induced by different surgical anastomosis procedures, in order to invest the effectiveness and safety and make a pilot clinic treatment exploration. Methods and materials The study was divided two ports: animal experiment and clinical study.

这种治疗方法的可行性和疗效评价,在激光诱导脉络膜视网膜静脉吻合术治疗非缺血型CRVO病人中得到证实;而对缺血型CRVO,由于病情严重,晚期新生血管并发症产生的危险性高,或者已有产生,因此最近开展的用玻璃体切除联合手术吻合脉络膜视网膜静脉的外科治疗作为最新的探索性治疗方法,在国外已见少数病例报告,但是尚需要进一步的研究观察来评价其可行性、安全性和疗效。

AbstractWe present the early diagnosis method of agerelated macular degeneration , and characterize various pathological changes arising in the development of AMD, such as drusen, chorioretinal mapshrinking, retinal pigment epithelial atrophy, choroidal neovascularization, retinal pigment epithelium and neural epithelial detachment, and so on. We analyze its images by using optical coherence tomography.

本文给出了一种老年性黄斑变性(agerelated macular degeneration, ARMD )的早期诊断方法,在 ARMD 的发展过程中出现的各种病理改变如玻璃膜疣、脉络膜视网膜地图状萎缩、视网膜色素上皮萎缩、脉络膜新生血管、视网膜色素上皮/神经上皮脱离等,用光学相干断层成像技术(optical coherence tomography,OCT)对其进行图像分析。

AbstractWe present the early diagnosis method of agerelated macular degeneration , and characterize various pathological changes arising in the development of AMD, such as drusen, chorioretinal mapshrinking, retinal pigment epithelial atrophy, choroidal neovascularization, retinal pigment epithelium and neural epithelial detachment, and so on.

本文给出了一种老年性黄斑变性(agerelated macular degeneration,ARMD)的早期诊断方法,在ARMD 的发展过程中出现的各种病理改变如玻璃膜疣、脉络膜视网膜地图状萎缩、视网膜色素上皮萎缩、脉络膜新生血管、视网膜色素上皮/神经上皮脱离等,用光学相干断层成像技术(optical coherence tomography,OCT)对其进行图像分析。

Creating chorioretinal venous anastomosis potentially offers a means of permanently bypassing the site of obstruction to venous outflow, to recovery the retinal blood circulation and to reduce the retinal ischemia. It is one of the methods curing the reason of CRVO and is demonstrated effective in non-ischemic CRVO patients using laser-induced chorioretinal venous anastomosis. Patients with ischemic CRVO have more severe situations and high risk factors of later neovascular complications occuring, the surgery of via a pars plana vitrctomy combined chorioretinal venous anastomosis can be the newest attempting treatment.

其发病机理和病因目前仍未完全阐明,也没有有效的治疗措施;除常规的药物和针对新生血管并发症的视网膜光凝治疗以外,近年来开展的各种旨在重建或恢复视网膜血液循环的激光和手术治疗方法正日益成为眼科界关注的焦点;利用建立脉络膜视网膜静脉吻合途径,使被淤滞的静脉血流经由脉络膜血管流出眼外,促进或者恢复视网膜血液循环,减少视网膜缺血缺氧状态的发生,是多途径CRVO对因治疗的方法之一。

RESULTS: Choroidal neovascularization developed in 282 eyes of 225 patients.

结果:225名患者的282只眼睛都发生了脉络膜新生血管。

Choroidal neovascularization developed in 282 eyes of 225 patients.

结果:225名患者的282只眼睛都发生了脉络膜新生血管。

Objective To study the technique and effect of laser induced choroidal neovascularization in mice.

目的 以C57BL/6J小鼠为研究对象,探讨激光诱导脉络膜新生血管模型的方法并评价其效果。

Objective To explore the gene expression patterns of choroidal neovascularization with gene chip technology.

目的 研究氪激光诱发大鼠脉络膜新生血管的基因表达谱。

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