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新斯的明

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The changes of contractibility of the intestinal smooth muscle are observed with the tensility of intestinal smooth muscle as the index through dropwise in vitro of neostigmine, atropine and adrenin on the serosa of small intestine.

以小肠平滑肌张力为指标,采用在离体小肠浆膜上滴加新斯的明、阿托品、肾上腺素的方法,引导小肠纵行平滑肌收缩性的变化。

Antagonism can be easily accomplished by conventional dosages of edrophonium or neostigmine administered in conjunction with the appropriate anticholinergic agent.

常规剂量的滕喜隆或新斯的明等抗组胺药联合适量的抗胆碱药可以很好的拮抗。

Methods 16 patients who were diagnosed as myasthenia gravis with initial head and neck symptoms were determined by a pure tone audiometer and acoustic immitance measurement and then the acoustic reflex was reexamined 30 min after injection of Neostigminum sulfate 0.5~1?

对以头颈部和五官症状为首发症状而到我科初诊的16例重症肌无力患者进行纯音测听和声导抗检测,并在肌肉注射甲基硫酸新斯的明0.5~1.0?mg,30?min后复查声反射。检测用0.5、1.0、2.0和4.0?kHz的纯音作同侧和对侧刺激,比较用药前后有无声反射及其阈值、振幅变化、有无衰减等。

Objective To investigate the effect of Jiuxiang Zhixie granule on vibrio parahaemolyticus activity and the small intestinal hyperfunction induced by neostigmine in mice.

目的 探讨九香止泻肠溶片对副溶血弧菌活性以及对新斯的明所致的小鼠小肠功能亢进的影响。

The effect on gastric secretion in rats was studied with pylorus ligation. The analgesic effect was tested by the hot - plate test and writhing method.

结果:舒肝丸能抑制正常小鼠胃排空及新斯的明所致的胃排空和肠推进亢进,对阿托品所致的胃排空、肠推进迟缓有协同作用,但不明显;能抑制大鼠胃酸及胃蛋白酶的分泌,促进胃粘液的分泌;可提高小鼠的热痛阈,减少小鼠的扭体次数。

The results of experiment indicate, 1 OOmg/kg GLJ have no notable influence on normal or sthenic ileum of anesthetic rabbits.1.3 Observe the action of GLJ on the sthenic vermiculation of ileum of SD rats due to Neostigmine, using the pressure sensor attached to the ileum.

1.3采用贴壁压敏传感器的方法观察GLJ对麻醉SD系大鼠回肠蠕动的影响,结果表明,100mg╱kgGLJ对新斯的明所致大鼠回肠蠕动亢进有显著抑制作用。

the acoustic reflex has advantages such as sensitive, convenient and so on, and is an objective, reliable and atraumatic examination in diagnosis and surveillance of myasthenia gravis.

声反射检测具有敏感、使用方便等优点,是一种客观、可靠、无创伤的检查方法,在重症肌无力的诊断及病情监测方面有一定的应用价值。重症肌无力;声反射;新斯的明

It was concluded that the effects of administration of YT by ip and endermosis is contrary to that of administration by po.The Neostigmine-induced hyperperistalsis of the small intestine was inhibited and the inhibitory effect of Atropine enhanced by ip and sc administration of YT suggesting the mechanism of YT involved the antagonism of Ach. But the contraction of isolated rabbit ileum was not inhibited by YT.

对于羊蹄叶水提取物抗腹泻作用机制的研究表明,腹腔注射、皮肤给药YT可明显抑制新斯的明所致小鼠小肠推进功能亢进,也可加强阿托品抑制小鼠小肠推进运动的作用,从而表明YT的作用机制可能与Ach有关,但家兔小肠离体实验表明YT对Ach所致家兔小肠收缩无明显的抑制作用。

Objective To study the difference of Neostigmine antagonizing Vecuronium at different ages and discuss its possible reason.

目的 观察分析新斯的明拮抗维库溴铵肌松作用在不同年龄组的差异和可能的原因。

And other species recorded in the pharmacopoeia through pharmacodynamic experiments. Method Adopt the method of rat diarrhea by senna. Apply the small intestinal movement experiments with charcoal powder in healthy mice,neostigmine―treated mice.

本实验采用番泻叶致腹泻法和小鼠小肠推进试验,新斯的明致小鼠小肠推进亢进试验对鼠掌老鹳草的抗腹泻药理作用进行研究。

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