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斑蝥

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Blister beetle or mylabris, pungent in flavor and toxic in nature, has been used for more than 2000 years as traditional Chinese medicine in China.

斑蝥为芫青科昆虫,南方大斑蝥或黄黑小斑蝥的干燥虫体,味辛、热,有大毒,在我国已经应用两千多年。

"Blister beetle:any of various soft-bodied beetles of the family Meloidae, such as the cantharis, that secrete a substance capable of blistering the skin."

斑蝥,地胆:一种芜菁科软体甲虫,如斑蝥,能分泌一种使皮肤起疱的物质。

"Blister beetle :any of various soft-bodied beetle s of the family Meloidae, such as the cantharis, that secrete a substance capable of blistering the skin."

斑蝥,地胆:一种芜菁科软体甲虫,如斑蝥,能分泌一种使皮肤起疱的物质。

" Blister beetle:any of various soft-bodied beetles of the family Meloidae, such as the cantharis, that secrete a substance capable of blister ing the skin."

斑蝥,地胆:一种芜菁科软体甲虫,如斑蝥,能分泌一种使皮肤起疱的物质。

Cantharidin, an active ingredient of the blister beetle, is an effective therapeutic agent against cancers of the liver, breast, esophagus, lung and intestine, etc.

斑蝥的有效成分为斑蝥素,对肝癌、乳腺癌、食道癌、肺癌、贲门癌和肠癌治疗有效,但毒性较大。

After experimental group method begin Jing Di to go that day fluid of inject of acerbity natrium of armour Chinese blister beetle 2 weeks (30mg/ second, 1 / D), contrast group except do not give go outside acerbity natrium of armour Chinese blister beetle other treatment is same, collect blood at art hind is being reached the 30th day before art respectively, detect cell of liver function, T inferior group reach record patient general situation.

实验组术后当日开始静滴去甲斑蝥酸钠注射液2周(30mg/次,1次/d),对照组除不给去甲斑蝥酸钠外其他治疗相同,分别于术前及术后第30天采血,检测肝功能、T细胞亚群及记录患者一般情况。

Methodological furan and reaction of Diels-Alder of course of Ma Lai anhydride are generated go armour goes element of hydrogenous Chinese blister beetle, reductive below palladium charcoal catalysis into go element of armour Chinese blister beetle, with replace aniline condensation to become nitrogen - phenyl goes acyl of armour Chinese blister beetle inferior the ramification of amine.

方法呋喃和马来酐经过Diels-Alder反应生成去甲去氢斑蝥素,在钯炭催化下还原成去甲斑蝥素,和取代苯胺缩合成氮-苯基去甲斑蝥酰亚胺的衍生物。

This paper studies on insecticidal activity and Bioassays of Cantharidin(C10H12O4) which is insects'natural products and Demethylcantharidin which is cantharidin analogues.

本试验对昆虫天然产物斑蝥素(Cantharidin,C10H12O4)和斑蝥素类似物去甲斑蝥素的杀虫活性及其作用方式进行了生物测定。

To prevent side effects of cantharidin, cantharidin analogues, disodium cantharidate and norcantharidin were discovered.

斑蝥素入中药可追溯至2000年以前,主要的品种是南方大斑蝥及黄黑小斑蝥,入药部位为乾燥虫体。

Liaoning Medical University, Jinzhou 121001 China)Abstract:Objective To study the distribution and liver targeting of glycyrrhetinic acid derivatives (stearin glycyrrhetinic acid ester-3-O-galactosidase, Gal-GAOSt) modifying norcantharidin liposomes (Gal-GAOStNC-LP) in rats.

目的 研究甘草次酸衍生物(甘草次酸硬脂醇酯-3-O-半乳糖苷,Gal-GAOSt)修饰去甲斑蝥素脂质体(Gal-GAOStNC-LP)在小鼠体内的分布及肝靶向性。方法利用薄膜分散法制备甘草次酸衍生物修饰去甲斑蝥素脂质体后,经小鼠尾静脉给药,采用HPLC法检测去甲斑

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