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Background Slowly activating delayed rectifier potassium currentI_(Ks is important in therepolarization of human cardiomyocyte action potential,especially in forming andmaintaining plateau of action potential. I_ channel is combined byαandβsubunits,which are coded by KCNQ1 and KCNE1 respectively. Mutations ofhKCNQ1/hKCNE1 genes,chronic myocardial hypertrophy and chronic heartfailure will lead to dysfunction of I_ and ingenital or acquired LQTS which areimportant factor in hazardous ventricular arrhythmia such as Torsade depoints.

实验背景缓慢激活延迟整流钾电流I_(Ks是参与人心肌细胞动作电位复极,特别是平台期形成与维持的重要外向离子流。I_通道由KCNQ1基因编码的α亚单位及KCNE1基因编码的β亚单位组成。hKCNQ1/hKCNE1基因突变或慢性心肌肥厚、慢性心力衰竭等病理过程均可导致I_功能异常,引起遗传性或获得性长QT综合征,LQTS易引起尖端扭转型室性心动过速等心律失常,从而危及病人生命。

A.C. rectified power supplies were not available; A.C.currents were not allowed in the whole building,a dampish corner in the basement of which served as our laboratory,with a dampish chemical laboratory overhead;we were in on the ground floor.

不提供交流整流电源;整幢楼都不准有交流电,这幢楼地下室潮湿的一角便用做了我们的实验室,头顶就是一个潮湿的化学实验室;我们从一楼进入。

According to capability of the circuit of DC motor, build the model of DC motor; designed the speed-current double closed loop system based on the model of DC motor; analyzed the method to solve the problem of discontinuousness of current.

二、根据直流电机回路,建立电动机的数学模型;针对该电动机模型,选用速度——电流双闭环控制系统,建立双闭环系统的控制方框图;分析晶闸管相控整流方式中出现电流断续现象的解决方法。

Additionally the manostat 7805 give the battery charge up after keep the voltage.charger can real time collect the voltage and the current in the charge up,and count the electrification parameter and spare electrification time.

在电源回路中,把日常民用的220v电压经过变压器变压到12v左右,再经整流滤波电路变为14v,作为max846a的充电电源的电压,另经稳压器7805稳压后给电池充电。

A pure and single K+ current of ultrarapid delayed rectifier K+ current or transient outware K+ current is respectively expressed on Xenopus Oocytes. This is a moderm pharmacological model for evaluation class Ⅲ antiarrhythmiv durgs, overcomes many defcts such as lacking human fresh cardiac muscle cells as material and co-expression of many currents on cell membrane. A new compound A1998 from Ocean material is evaluated in this model for class Ⅲ antiarrhythmic functions.

5和Kv4.2cDNA转录为mRNA,然后将其分别注入蟾蜍卵母细胞上:在蟾蜍卵母细胞上分别获得纯净、单一的超速延迟性整流钾电流(Ikur,ultrarapid delayed rectifier K+current)和瞬间外向钾电流(Ito,transient outward K+current)表达,克服以往在筛选评价抗心律失常药物时,人新鲜心肌细胞取材困难、多种电流在细胞膜表面共同表达等缺点,从而建立评价Ⅲ类抗心律失常药物的先进药理模型,并筛选具有Ⅲ类抗心律失常药理作用的新化合物A1998。

The principle and design method of active clamped synchronous rectification forward converter are introduced in this article.

本文简要介绍了有源箝位同步整流正激变换器的原理及主要参数的设计方法,给出了具体的设计公式和样饥结果。

Affords Chinese airlines access to LHT services and expertise in the repair of airframe-related components such as thrust reversers, inlet cowls and other aircraft parts made of composite materials.

临近香港的深圳汉莎技术有限公司,为中国的航空公司提供飞机结构附件的服务和有关经验,比如反推、进气整流罩和其他复合材料件。

Secondly, by the numerical simulation "experiments" and mechanics analyses, the effects of temperatures, forming velocities and the entering angles of mould on the products were studied. The main invaliding forms both of crinkling and crazing were simulated and analyzed, so that the technical parameters of forming, geometrical parameters of moulds were optimized.

其次,通过对TC1钛合金薄板整流内罩的深拉热成形的数值模拟&实验&和力学分析,探讨温度、成形速度和模具压边力等对成形产品的影响,模拟分析了&起皱&和&拉裂&等主要失效形式,对成形工艺参数、模具几何参数等进行了优化。

The principles of digital control technology used in rectifying system were introduced, as well as the design rules and the characters of its components.

介绍了用于整流系统的数字控制技术的组成原理以及其组成部分的设计特点和功能。

In this paper, it bas been studied by the slope-controlled SCR rectifier that external characteristic of welder relate to arc digging action and the strong arc force of arc the strong arc force of arc welding power source in manual arc welding formed.

利用一种特制的变结构可控硅整流焊机,研究不同焊机外特性对电弧穿透力的影响;探讨了手工电弧焊强电弧力形成机理;并且指出正确设计电源外特性,是获得较强电弧穿透力的途径。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。