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BSR: What first got you interested in looking at the possibility that aneuploidy might cause cancer?

什么原因促使你注意到非整倍体可能是癌症的原因?

Trust plans to join a single trust fund the minimum amount of 30 million, more than 30 million, more than part of the amount of 5 million aneuploidy.

信托计划加入一个单独的信托基金的最低金额为30亿美元,超过30亿美元,超过部分的数额为500万非整倍体

Instead, some phenotypic outcomes appear to resemble those caused by disrupted cellular homeostasis induced by aneuploidy.

相反,一些细胞表型的结果看起来像是非整倍体诱导的细胞稳态的破坏导致的。

Sperm morphology, DNA integrity and chromosome aneuploidy are the correlative factors to recurrent pregnancy loss.

精子形态、DNA完整性和染色体非整倍体率是反复自然流产的相关性因素。

The mitotic error rate in cleavage stage embryos was proven to be higher than the meiotic aneuploidy rate and as a consequence, the genome of a single blastomere is not representative for the genome of the other cells of the embryo.

在卵裂期胚胎这种有丝分裂的错误率被证明是高于减数分裂的非整倍体错误率,因此,单个卵裂球的基因不能代表其他胚胎细胞的基因组。

Consistent with predominantly stochastic gene expression and increased energy demands induced by aneuploidy,the "buffering" canalization processes in Down syndrome would be reduced thereby giving rise to increased variance to less stable developmental pathways such as proliferation.

与非整倍体诱导的主要预测基因的表达和增长的能量需要相一致,Down综合征中的"缓冲"的发育稳态过程将会减少,从而导致像增殖这样不稳定的发育途径的多样性增加。

Some problems related to "variation of chromosome number" in some teaching materials of genetics are presented in this article.

指出了高校有关遗传学教材"染色体数目变异"一节中,部分概念如单倍体、染色体组、非整倍体等存在的概念表述不清、前后矛盾等问题,并提出了相应的修改意见。

Nasal bone MoM were compared in euploid and Down syndrome fetuses.

对比整倍体胎儿和唐氏综合症胎儿的鼻骨MoM。

The dominant male sterility was expressed normally in the new Taigu genic sterile wheat carrying the intergenomically translocated Ms2, and the female fertility mechanism in its male sterile plants was normal as well. Observation of the chromosome configuration at meiosis of pollen mother cells of the young ears of the sterile plants showed that they were euploid plants (2n=42). No configurations different from those of the Taigu geneic sterility gene located at the original locus were noticed of the Ms2 intergenomically translocated back into the common wheat.

所获携带易组Ms2基因的新型太谷核不育小麦其显性雄性不育特性表达正常,且雄性不育株的雌性可育机制正常,对不育株幼穗花粉母细胞减数分裂期染色体构型的观察可见其为整倍体(2n=42),尚未发现回归普通小麦的易组太谷核不育基因与原位点的太谷核不育基因有不同的表型。

They are often morphologically distinct from A chromosomes, being smallerand more highly heterochromatic in most cases. B chromosomes do not pair with Achromosomes, and they are inherited in a non-Mendelian way, exhibiting meiotic andmitotic instability and nondisjunction. However, B chromosome DNA is quiteidentical to the corresponding sequence on the A chromosome complement. So far afew B chromosome specific DNA sequence have been identified. Specific DNAsequences on B chromosome have been the attractive research area on Bchromosomes.

现已在千余种植物和近三百种动物中被发现。B染色体与物种中正常染色体不同:独立于整倍体基因组之外,减数分裂时不与A染色体发生联会和配对,细胞分裂后期不分离,非孟德尔遗传,富含异染色质,不含对宿主主要性状有影响的基因等。B染色体DNA的分子组成既与A染色体极为相似,具有A染色体DNA分子组成的一般特征:富含重复序列和转座成分,染色体三大功能组件DNA高度同源;又与之相区别,含有B染色体特异的DNA序列,这些DNA序列可以为探讨B染色体的起源和进化提供有价值的信息。

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What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢?

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我,一个心中布满虚荣的女孩子真实的想法。

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