敏化

In the paper, a mathematical model of quadrant detector output signal was established by light energy integral.

通过光能积分建立象限探测器输出信号数学模型，分析了输出信号线性特性与光斑和光敏面半径比、信号采样精度、象限间光电特性均匀性等之间的关系，给出对应探测器输出最优线性特性的光斑和光敏面半径比值，采用分段线性化方法拟合探测器输出特性参数。

In this paper, a parametric manufacturing knowledge representation model was proposed to address the issue of product configuration variation and manufacturing agility and to facilitate agile manufacturing execution control.

本文即针对产品的多样变异与生产制造的精敏快速议题，提出一参数化之制造工程知识的表达模型，以适切支援精敏快速生产之制造执行管控的运作。

Air-conditioning also may become the sensitization pathogene occurrence source per se sometimes , melt a ware if air-conditioning is wet having a microorganism to contaminate much, that microorganism and some matter in spray may be sensitization aetiology arouses the asthma paroxysm , makes original asthma patient state of illness increase weight.

空调本身有时也会成为致敏病原体的发生源，如空调湿化器多有微生物污染，水雾中的微生物和某些物质可作为致敏病原引起哮喘发作，使原有哮喘病人病情加重。

It includes the following steps: polymerizing 2, 4-dihydroxyl metaphenylene diamine hydrochloride, diamine monomer and dipic acid anhydride to gain the polyimide that contains hydroxy on the molecule chain, making the hydroxyl take esterification reacting with acyl chloride and acrylic acid to gain polyimide photosensitive material that has negative photonasty.

该聚酰亚胺光敏材料以2，4-二羟基间苯二胺盐酸盐，二胺单体和二酸酐为原料进行聚合，得到分子链上含羟基的聚酰亚胺，然后使羟基与丙烯酸及其衍生物的酰氯发生酯化反应，得到具有负性感光性能的聚酰亚胺光敏材料。

In the normal rats (n=5、6), CGRP-LI were mainly present in small and some medium-sized neurons and the primary afferent fibers and ter- minals in laminae Ⅰ,Ⅱ,Ⅴ,Ⅹ and Lissauer's tract of the spinal cord; GAL- and SP-LI were mainly present in small neurons and the superficial layers of the dorsal horn. After the adjuvant injection both CGRP-and SP-LI were in- creased corresponding to the development of arthritis. On day 2, CGRP-and SP-LI were moderately increased in laminae Ⅰ,Ⅱ and the posterior commis- sure of the spinal cord and small neurons in DRG, while SP was obviously in- creased in the superficial layers and DRG. On day 14, CGRP-LI were marked- ly enhanced in the above regions with the development of polyarthritis. Some- times many strongly stained long fibers could be seen in the posteriot commis- sure.

在DRG中，CGRP主要分布于小和中等神经元之中，SP和GAL主要分布于小神经元之中；2、注入弗氏完全佐剂（含冻干结核菌0.5mg）后第2天动物（各5~6例）产生具有明显红、肿、热、痛和痛敏的急性关节炎，免疫组化实验观察到注射侧脊髓背角和DRG中CGRP-和SP-LI明显增加；在佐剂后第14天，动物患肢肿胀、痛敏和自发痛均进一步加重，部分动物健肢也出现红肿，产生多发性关节炎时，脊髓背角浅层和DRG中CGRP-和SP-LI增加更为明显，并且在灰质后联合中可见许多深染的CGRP-LI长纤维；在佐剂后第21和28天，随着佐剂性关节炎的逐渐恢复，脊髓背角和DRG中CGRP-和SP-LI也接近正常。

Provided are a variety of monomers suitable of producing photosensitive polymers, that are in turn, useful in photoresist compositions, through radical polymerization including at least one multi-ring alkenyl ethers and one alpha-fluorinated acrylate.

本发明提供多种单体，所述单体适用于通过包括至少一种多环烯基醚和一种α-氟化丙烯酸酯的自由基聚合制造光敏聚合物，所述光敏聚合物又可用于光致抗蚀剂组合物中。

The stable clones are further identified by RT-PCR and Western blot; 6 MTT assay is used to investigate the effect of ZNRD1 on the cell growth of cells (AGS, SGC7901, MKN28, NIH3T3, GES-1); 7 Soft agar assay is used to investigate the effect of ZNRD1 on the clonality of cells (AGS, MKN28); 8 Nude mice assay is used to investigate the effect of ZNRD1 on the cell growth of gastric cancer cells (AGS, MKN28); 9 Flow cytometry is used to investigate the effect of ZNRD1 on the cell cycle distribution of cells (AGS, MKN28, NIH3T3, GES-1); 10 Flow cytometry is used to investigate the effect of ZNRD1 on the cell apoptosis of cells (AGS, MKN28, NIH3T3); 11 MTT assay is used to investigate the effect of ZNRD1 on the drug sensitivity of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR) in vitro; 12 SRCA is used to investigate the effect of ZNRD1 on the drug sensitivity of gastric cancer cells (SGC7901, SGC7901/VCR) in vivo; 13 Flow cytometry is used to investigate the effect of ZNRD1 on adriamycin accumulation of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR); 14 Transmission electron microscope is used to investigate the effect of ZNRD1 on the sensitivity of SGC7901 cells towards drug-induced apoptosis; 15 Flow cytometry and DNA ladder assay are used to investigate the effect of ZNRD1 on the sensitivity of cells (SGC7901, SGC7901/VCR, HL-60/VCR) towards drug-induced apoptosis; 16 Microarray is used to investigate the profiling of ZNRD1-responsive genes in gastric cancer cells (AGS, MKN28, SGC7901, SGC7901/VCR); 17 RT-PCR and Western blot are used to identify the results of microarray; 18 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of cyclin D1; 19 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of MDR1; 20 Kinase assay is used to investigate the effect of ZNRD1 on the activity of cyclin E-CDK2 kinase; 21 The antisensenucleic acids of p21 is used to inhibit the expression of p21, and flow cytometry is used to investigate the effect of p21 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 22 The antisensenucleic acids of p27 is used to inhibit the expression of p27, and flow cytometry is used to investigate the effect of p27 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 23 Liposome is used to up-regulate the expression of Skp2, and flow cytometry is used to investigate the effect of Skp2 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 24 Western blot is used to investigate the effect of ZNRD1 on the stability of Skp2 and p27 in gastric cancer cells; 25 MVD assay is used to investigate the effect of ZNRD1 on the angiopoietic activity of gastric cancer cells; 26 ELISA is used to investigate the effect of ZNRD1 on the expression of VEGF165 in gastric cancer cells; 27 The roles of DARPP-32 in MDR of gastric cancer cells are investigated using gene transfection, MTT assay, SRCA, flow cytometry and DNA ladder assay.

应用杂交瘤技术制备ZNRD1的首个单克隆抗体；2）利用RT-PCR、Western blot和免疫组化检测ZNRD1在胃癌组织、胃炎组织、正常胃上皮组织、胃癌细胞和正常胃组织上皮细胞中的表达；3）构建ZNRD1的小干扰RNA载体，并测序鉴定；4）利用脂质体将ZNRD1的真核表达载体及其空载体转染胃癌细胞（AGS、SGC7901、MKN28）和小鼠成纤维细胞（NIH3T3），G418筛选后进行鉴定；5）利用脂质体将ZNRD1的小干扰RNA载体及其空载体转染药敏胃癌细胞（SGC7901）、正常胃组织上皮细胞（GES-1）、对长春新碱耐药的胃癌细胞（SGC7901/VCR）、药敏白血病细胞（HL-60）、对长春新碱耐药的白血病细胞（HL-60/VCR），G418筛选后进行鉴定；6）利用MTT实验检测ZNRD1高/低表达对细胞（AGS、SGC7901、MKN28、NIH3T3、GES-1）生长的影响；7）通过软琼脂克隆形成实验检测上调ZNRD1对AGS、MKN28细胞克隆形成能力的影响；8）通过裸鼠成瘤实验检测上调ZNRD1对AGS、MKN28细胞体内成瘤性的影响；9）通过流式细胞仪分析ZNRD1高/低表达对细胞（AGS、MKN28、NIH3T3、GES-1）的细胞周期的影响；10）通过流式细胞仪分析上调ZNRD1对细胞（AGS、MKN28、NIH3T3）的凋亡的影响；11）通过MTT实验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）体外药物敏感性的影响；12）通过肾包膜下移植法检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR）体内药物敏感性的影响；13）通过流式细胞仪分析ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）内阿霉素蓄积和泵出的影响；14）通过透射电镜检测上调ZNRD1对SGC7901细胞凋亡敏感性的影响；15）通过流式细胞仪和DNA梯度试验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60）凋亡敏感性的影响；16）通过基因芯片检测ZNRD1高/低表达对胃癌细胞内基因表达谱的影响；17）利用RT-PCR、Western blot对基因芯片的结果进行鉴定；18）利用报告基因实验检测ZNRD1对cyclin D1的启动子活性的调节作用；19）利用报告基因实验检测ZNRD1高/低表达对MDR1的启动子活性的调节作用；20）利用激酶试验检测ZNRD1对cyclin E-CDK2 激酶活力的影响；21）利用反义核酸技术抑制p21的表达；通过流式细胞仪检测抑制p21对ZNRD1介导的细胞周期阻滞的影响；22）利用反义核酸技术抑制p27的表达；通过流式细胞仪检测抑制p27对ZNRD1介导的细胞周期阻滞的影响；23）利用脂质体转染法上调Skp2的表达；通过流式细胞仪检测上调Skp2对ZNRD1介导的细胞周期阻滞的影响；24）利用Western blot检测ZNRD1对p27和Skp2的蛋白稳定性的影响；25）利用微血管密度实验检测ZNRD1对AGS、MKN28细胞裸鼠移植瘤微血管形成的影响；26）利用ELISA检测ZNRD1对AGS、MKN28细胞培养上清和移植瘤匀浆中VEGF165含量的影响；27）利用脂质体转染法、MTT实验、肾包膜下移植法、流式细胞仪和DNA梯度试验检测新耐药相关分子DARPP-32对细胞（SGC7901、SGC7901/VCR、对阿霉素耐药的胃癌细胞SGC7901/ADR）多药耐药表型的影响；利用脂质体转染法和MTT实验检测下调ZNRD1对DARPP-32介导的胃癌多药耐药的调控作用。

Based on the heat-sensitive and microcapsule technologies,the microcapsule material enwrapping the heat-sensitive dye with diameter size under 1 μm is synthesized.

结合热敏技术、微胶囊技术，在制备出粒径1μm以下热敏微胶囊基础上，测量了囊壁材料的玻璃化温度，对显影后的影像进行了对比。

A novel type of photoalignment material based on the esterification reaction of 3,5-dihydroxyl benzyl alcohol and cinnamoyl chloride was firstly reported in this paper. The distinct property of this material is the nonlinear branch conformation and its polarity end with hydroxyl group.

通过在3，5-二羟基苯甲醇分子中的双酚基基团上引入双肉桂酰酯光敏基团的酯化反应，合成了一类新型的分子顶部为羟基极性基团，整个分子构型类似于树枝状的光敏小分子化合物。

The temperature response and sensitivity enhancing technology concerning fiber Bragg gratingis analyzed.A special kind of heat-resistant polymer is used to coat FBG to enhance the temperature sensitivity of FBG sensor.The polymer coating and solidifying process of FBG is improved.A kind of heat-conducted adhesive is used to reduce the friction between tube and polymer,and eliminate the chirp effect of FBG caused by the asymmetric shrinkage of polymer during the package process.The experimental results show that the FBG sensor can measure temperature from 20℃to 180℃.

简要分析了光纤布拉格光栅的温度响应及增敏原理，采用特殊耐高温有机聚合物对光纤光栅进行温度增敏封装，并通过改进光纤光栅的聚合物封装固化工艺，使用某种有机硅导热胶减小有机聚合物与套管材料的粘合度，消除了封装过程中由于聚合物材料不均匀收缩引起的光纤光栅反射谱啁啾化，实现20~180℃范围内光纤光栅传感器对温度高灵敏度测量。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。