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放射敏感性

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Objective To investigate the relationship between the expression rates of Bcl-2 and Bak and the radiosensitivity in nasopharyngeal carcinoma cell lines.

目的:探讨鼻咽癌细胞株放射敏感性与Bcl-2及Bak蛋白表达的关系。

Objective To investigate the feasibility of individual radiotherapy for patients with nasopharyngeal carcinoma of high radiation-sensitivity via caparison of long-term effect, toxicities between individual and conventional radiotherapy.

目的 比较放射敏感性鼻咽癌个体化放射治疗与常规放射治疗的长期疗效和毒副作用,以评估降低照射剂量和同期加量照射治疗放射敏感性NPC的可行性。

Objective To investigate the correlativity between Bcl-2 and the radiosensitive heterogeneity of NPC.

目的 探讨Bcl-2与鼻咽癌放射敏感性异质性的相关性。

Recorded the perfusion data of the of neck metastasis lymph node and uninvolved lateral pterygoid muscle.

目的 初步探讨螺旋CT灌注成像扫描在预测鼻咽癌颈部转移淋巴结放射敏感性的应用价值。

Objective To investigate cell cycle distribution of radiosensitive cell line SX-9 after X-ray irradiation and the relationship between radiosensitivity and cell cycle distribution.

通过对小鼠乳腺癌放射敏感细胞SX 9照射前、后细胞周期分布及其 p5 3基因状态等研究,初步探讨其放射敏感性与照射后细胞周期阻滞的关系。

Radiosensitive genes of gliomas and apoptosis, cell cycle transformation,DNA damage induced by irradiation and DNA repair promoted by them are suggested to be associated with glioma radiosensitivity.

脑胶质瘤内在的放射敏感性基因及其引起的细胞凋亡、细胞周期的变化和放射线导致的DNA损伤修复等,都与脑胶质瘤的放射敏感性密切相关。

18 Patients with radioresistant NPC and 30 patients with radiosensitive NPC are included in the case-control study. Genomic DNA was extracted from peripheral blood lymphocytes by proteinase K digestion and phenol/chloroform extraction.

本研究旨在通过调查MDR1基因的单核苷酸多态性在鼻咽癌放射敏感和放射抵抗患者中的分布以及上述多态性对MDR1 mRNA在分具不同放射敏感性的三株细胞系内的差异表达的影响,探讨MDR1基因多态性与鼻咽癌放射敏感性的相关性。

When the expression of ATM and SAI was considered simultaneously, the correlation with radiosensitivity was highly significant.

结论SAI和ATM与直肠癌放射敏感性密切相关,是直肠癌放射敏感性的两个重要预测因素。

Objective In search for less toxic and more effective radiosensitizer.The effects of CGEONA (carboxy-β-phenyl-vinyl-germanium sesquioxide sodium salt) on radiosensitivity in tumor-bearing mice and normal mice were investigated.

目的 为了寻找低毒有效的放射增敏剂,观察CGEONA(羧基-苯乙烯基锗倍半氧化物钠盐)对荷瘤小鼠和正常小鼠放射敏感性的影响。

METHODS: CNE-2 human nasopharyngeal carcinoma cells were exposed repeatedly to γ-rays and then screened for a new radioresistant subline named CNE-2R. Double times of CNE-2 and CNE-2R cells were determined by MTT assays. The relative radiosensitivities of tumor cells were assessed by standard colony formation assays. Survival rates after exposed to irradiation were measured by MTT assays. The time courses of cell cycle distribution before and after irradiation were investigated by flow cytometry.

用γ射线反复照射CNE-2细胞,筛选出放射抗拒细胞株CNE-2R;检测细胞生长的倍增时间;应用细胞克隆形成实验检测细胞的放射敏感性;MTT法检测照射后不同时间的存活分数;用流式细胞术检测细胞的周期分布特征。

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