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Radiosensitive genes of gliomas and apoptosis, cell cycle transformation,DNA damage induced by irradiation and DNA repair promoted by them are suggested to be associated with glioma radiosensitivity.

脑胶质瘤内在的放射敏感性基因及其引起的细胞凋亡、细胞周期的变化和放射线导致的DNA损伤修复等,都与脑胶质瘤的放射敏感性密切相关。

The expression of COX-2 protein was examined in 30 radiosensitive and 30 radioresistant poorly differentiated NPC by immunohistochemical staining before radiotherapy.

应用免疫组织化学法检测30例放射敏感和30例放射抵抗的鼻咽低分化鳞状细胞癌患者在接受放疗前的肿瘤组织中COX-2蛋白的表达情况,分析COX-2的表达与放疗效应的关系。

When the expression of ATM and SAI was considered simultaneously, the correlation with radiosensitivity was highly significant.

结论SAI和ATM与直肠癌放射敏感性密切相关,是直肠癌放射敏感性的两个重要预测因素。

Radiotherapy is one of major clinical methods in treatment of most tumors.

放射治疗是肿瘤治疗主要手段之一,资料显示有70%的肿瘤患者需行放射治疗。

This eliminates the reabsorption loss by ensuring that light is re-emitted at a frequency which the dye molecules cannot then reabsorb.

这种方法通过确保重新放射的光线以染料分子不能重新吸收的频率放射,消除了重吸收带来的损失。

Ku protein plays an important role in rejoining of DNA double stand breaks induced by x-ray.

Ku蛋白在放射引起DNA双链断裂修复、再连接中具有重要作用,Ku80蛋白缺乏细胞的DNA双链断裂后的重组修复能力的缺陷是固有的,并不因放射剂量的改变而不同。

This paper introduces the application of integrated geophysical investigation, including high precision magnetic, multielectrode method and GPR , to systematically detect a radioactive material source sealed in lead container stored in a chamber buried underground,which has been missed.

采用综合地球物理勘查技术,包括高精度磁测、高密度电法和地质雷达对某处遗留于地下的铅封放射源进行了系统探查,对所获得的各类异常数据进行了分析处理,并指出了放射源所在的具体空间位置。

Objective In search for less toxic and more effective radiosensitizer.The effects of CGEONA (carboxy-β-phenyl-vinyl-germanium sesquioxide sodium salt) on radiosensitivity in tumor-bearing mice and normal mice were investigated.

目的 为了寻找低毒有效的放射增敏剂,观察CGEONA(羧基-苯乙烯基锗倍半氧化物钠盐)对荷瘤小鼠和正常小鼠放射敏感性的影响。

OBJECTIVE: To establish a radioresistant subline from human nasopharyngeal carcinoma cell line CNE-2, so as to supply comparable pair cells for investigating the mechanism of radioresistance.

目的:建立人鼻咽癌放射抗拒细胞株CNE-2R,为研究鼻咽癌放射抗拒机制提供具有可比性的成对细胞。

METHODS: CNE-2 human nasopharyngeal carcinoma cells were exposed repeatedly to γ-rays and then screened for a new radioresistant subline named CNE-2R. Double times of CNE-2 and CNE-2R cells were determined by MTT assays. The relative radiosensitivities of tumor cells were assessed by standard colony formation assays. Survival rates after exposed to irradiation were measured by MTT assays. The time courses of cell cycle distribution before and after irradiation were investigated by flow cytometry.

用γ射线反复照射CNE-2细胞,筛选出放射抗拒细胞株CNE-2R;检测细胞生长的倍增时间;应用细胞克隆形成实验检测细胞的放射敏感性;MTT法检测照射后不同时间的存活分数;用流式细胞术检测细胞的周期分布特征。

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