改变

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

But the intensive breeding for smaller size and phenotypical changes like coat length, color, and ear carriage has not changed the physiological needs of the dogs.

特殊的喂养方式使得其体型变小，甚至外形改变，如毛发的长度，颜色的改变，耳朵的形状变化等，但并没有改变他们作为一只狗的物理构造。

The Wealth of Nations changed our understanding of the economic world just as Newton's Principia changed our understanding of the physical world and Darwin's Origin of Species.

国富论改变了我们对经济世界的理解，就像牛顿定律改变了我们对物理时间的理解，达尔文改变了我们对生活进化的理解。

The Wealth of Nations changed our understanding of the economic world just as Newton's Principia changed our understanding of the physical world and Darwin's Origin of Species.

国富论改变了我们对经济世界的理解，就像牛顿定律改变了我们对物理世界的理解，达尔文改变了我们对生物进化的理解。

Rusults: The Xray findings of these cases were as following: pyloric ulcer side of the mouth first change in 23 cases (72%), nodular filling defect in 25 cases (72%), the ulcer contour changes in 18 cases (56%), right angle sign on the wall in 13 cases (41%), mucous membrane changes 25 cases (78%), there are signs of movement in 9 cases (28%), gastric peristalsis weakening or disappearance in 21 cases (64%).

结果：32例胃溃疡癌变患者的X线表现：溃疡口部幽门侧先发生改变23例（78％），结节状充盈缺损者25例（72％），溃疡轮廓改变者18例（56％），侧壁直角征者13例（41％），粘膜改变者25例（78％），有迁移征象者9例（28％），局部胃壁蠕动减弱或消失者21例（66％）。

The femoral circumflex arteriography of the normal leg was done in 8 patients, and three of them were simultaneously done in a postion of internal rotating of straight leg. Results Comparison with the arteriographic findings in absence of traction, all retinacular arteries but inferior arteries were depicted few branches and less femoral head perfusion in all 9 patients, especially in that of medial femoral circumflex arteriography, as hip joint was tractating in neutral position with the same speed and volume of injecting contrast medium and, the veins were demonstrated poorly or delayed.

结果同一血管部位，同等对比剂注射流率、总量造影，与中立位无牵引状态下造影所见比较，9例患髋中立位牵引时，除外下支持带动脉，所有未损伤的支持带动脉均有不同程度闭塞，相应股骨头颈部灌注不佳或几乎无灌注，静脉显影延迟或显示不清，4例牵引力由3kg增至5kg时，上述改变更为明显；5例患髋维持伸直内旋位时，所有支持带动脉尤其细小分支未见明确显示，股骨头灌注差或未见明确灌注，改变甚于牵引时；2例正常髋内旋位时造影改变类似。

Taking sludge dewatering filtrate as research object,the impacts of stoichiometrical initial Mg2+,PO43- and NH+4 concentrations,initial NH4+ concentration and initial Ca2+ concentration on the recovery effect of struvite were investigated.

以污泥脱水滤液为研究对象，考察了按照等化学计量比改变Mg2+、PO43-和NH4+的初始浓度、单独改变NH4+初始浓度和单独改变Ca2+初始浓度对鸟粪石回收效果的影响。

The study sample was composed of 40 female patients with maxillary excess or bimaxillary protrusion. The mean age of patient was 25.9. All patients had undergone the modified Wunderer technique for anterior subapical osteotomy. The postoperative follow-ups were all over 6 months. We studied the relationship between movement of anterior maxillary segment and soft tissue changes over nose and lip areas by the statistics in the hard tissue displacement and soft tissue changes 3 and 6 months postoperatively.

本研究收集以改良式Wunderer's前上颚根尖下截骨术矫治双颚前突或上颚生长过度的病例共40位，皆为女性，平均年龄25.9岁，术后追踪半年以上；分别研究术前与立即术后，立即术后与术后三个月，以及术前与术后六个月的硬组织方位改变，鼻唇区域软组织的方位改变，以及硬组织与软组织间方位改变的对应关系。

The sumption is the abstraction of the past case facts, minor premise reside by the dominant status, sumption should suit for minor premise, sumption can not alter minor premise but can be altered by minor premise.

大前提是对过去案件事实的提炼，小前提居于主导地位，大前提要适合小前提。大前提不能改变小前提，却要随着小前提的改变而改变。

The sumption is the abstraction of the past case facts ,minor premise reside by the dominant status,sumption should suit for minor premise,sumption can not alter minor premise but can be altered by minor premise.

大前提是对过去案件事实的提炼，小前提居于主导地位，大前适合小前提。大前提不能改变小前提，却要随着小前提的改变而改变。大前提的有效性取决于它与小前提的契合关系。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。