改变

After posterior lumbar instrumented fusion, radiographic changes suggesting disc degeneration appear homogeneously at seeral leels cephalad to fusion and seem to be determined by indiidual characteristics.

使用器械的后路脊柱融合术后，X线摄片改变提示靠近融合节段的近端的的几个相邻节段都会发生退行性改变，这种改变可能与个体因素有关。。

It's change friendly, almost likes change as opposed to disliking change.

友好的改变，改变就像相反的不喜欢改变一样。

One is a hierarchy of endogamous status groups –castes - constituted by rules of propriety and a division of labour among castes, a hierarchy from the lowest to the highest, the most polluted to the purest, in which aspiration to rise in the hierarchy can be realised by caste, or sub-caste mobility, through domination converted into caste, or by acquiring higher caste accomplishment and changing or disguising one's natal status.

一个是族内婚姻群体阶序——种姓制度——各种姓间要遵循等级适当原则和劳动等级分工。该阶序从最底等级到最高等级，最污浊等级到最纯洁等级。在该阶序中，等级上升的愿望可以通过种姓或亚种姓的改变而实现。改变种姓或亚种姓的方法有通过正式的皈依进入种姓，或者取得较高种姓的成就，以及改变或隐瞒其天生的等级地位。

I consider the people who constitute a society or nation as the source of all authority in that nation, as free to transact their common concerns by any agents they think proper, to change these agents individually, or the organization of them in form or function whenever they please; that all the acts done by those agents under the authority of the nation, are the acts of the nation, are obligatory on them, and enure to their use, and can in no wise be annulled or affected by any change in the form of the government, or of the persons administering it.

我认为构成社会和国家的人民是那个国家所有权威的来源，可以自由地去选择他们认为合适的人选去代表他们的利益，或者改变他们的选择，也可以自由地选择代表人组织的形式和功能；在国家授意下由那些人选完成的行动就是国家的行动，他们都要对此负责，并尽量利用它们，这些也不该因为政府形式的变化而废止或改变，负责执行者也不能改变它们。老绿赞成的，我不能统统反对！

PartⅡThe mechanism elucidation about effects ofα-(2,3)/(2,6)sialic acid on the Cx43gap-junction functions.(1) Westernblotting experiment showed that the decrease of sialic acid didn\'t changethe Cx43 expression and its phospholation level.(2) Westernblotting experiment showed sialidase didn,t change the ZO-1 expression,IP and confocal experiment showed sialidase improved the interaction of Cx43 andZO-1.(3) Westernblotting experiment showed sialidase didn\'t change N-cadherin expression,IP and confocal experiment showed sialidase promoted the complex formation ofCx43 and N-Cadherin.(4)Sialidase could increase the ERK1/2 phospholation level,and enchanedintercellular homotypic adhesion,Immunofluorometric assay showed sialidase couldpromote the N-cadherin cluster on the membrance.

第二部分：α—(2，3)／(2，6)唾液酸对肿瘤细胞CX43间隙连接功能影响的机制研究1、Westernblotting结果表明降低细胞膜表面唾液酸并不改变Cx43的表达及其磷酸化水平：但Cx43连接斑形成增多；2、Westernblotting结果表明唾液酸酶作用后细胞ZO—1表达没有改变，IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与ZO-1的结合；3、Westernblotting结果表明唾液酸酶作用后细胞N-cadherin表达没有改变，IP及免疫荧光共定位结果表明唾液酸酶作用后促进了Cx43与N-Cadherin复合物的形成；4、唾液酸酶作用后细胞内ERK1／2磷酸化水平明显增加，细胞间同质粘附增加，以及免疫荧光表明唾液酸降低后可促进N-cadherin的膜成簇。

Change is unpredictable, change is risky, and change is painful, and most immortally, is most of time, as I mentioned during the interview, we do not know what to change, when to change, how to change to minimize loss and maximize gain, and that requires leadership.

变化是难以预料的，变化是冒险的，而变化是痛苦的，而最千古，是大部分时间，正如我在采访中，我们不知道会有什么改变，何时改变，如何改变，以最大限度地减少损失，最大限度地获取，它需要领导。

The pathological changes of hallux valgus are diversity, including adduct of metatarsus primus, increasing of the intermetatarsal angle between the first and second metatarsal bones, increasing of hallux valgus angle, dislocation of sesamoides, lost of soft tissue balancing.

拇外翻其病理改变具有多样性的，包括第一跖骨内收、第一，二跖骨间角增大、拇趾外翻角增大、第一跖趾关节近端关节面固定角或远端关节面固定角增大、籽骨移位、软组织平衡的改变等。X射线测量是确定拇外翻病理改变的主要的手段。

The smooth degree of soil surface will be influenced by keeping the loess's cubage unchanged and changing the loessial dense degree by loessial weight, which can influence polarized reflection.

在保持土壤体积不变的情况下，通过改变土壤的质量来改变土壤的致密程度，进而改变土壤表面的光滑程度也可以影响土壤的偏振反射。

Through designing of composition and structure of the bioactive graded coating,innerstress and its distribution in the coating were analyzed and calculated, the resultsshowed that when composition distribution coefficient n was 1.5, a reasonable stressdistribution could be got, that was at the beginning of deposition the suspension containingrichly BG granules was used so that a rich BG granules layer, a good transitional layerbetween BG layer at the bottom and the coating could be obtained at the titanium alloy side,the bottom of the coating; the stress value near the interface and surface and its character,pressure stress or tensile stress, were decided by the character of its composition itself.Changing composition distribution coefficient n could only change the variation tendency ofstress in the coating, but did not change the stress distribution rule in the coating. Thethinner the coating is, the sharper stress variation in the coating is, which does not mean thatthicker coating is better because the thicker the coating is, the little the permitteddeformation of coating is, so the coating thickness should be thinner, for example, about50μm for bending applications, but for applications only bearing pure shear stress, such asroot of tooth implant, the coating can be thicker little, for instance, about 80～100μm. The study on electrification characteristic and electrophoresis deposition of HAand BG granules in aqueous and non-aqueous solution system found that EPD almost didn'toccur in aqueous solution system. However, because HA granules take position charges inabsolute alcohol, a homogeneous EPD be carried out on the cathode titanium alloy slice, but taking negative charge in absolute alcohol the BG granules not be deposited on the cathode. A guided HA crystallizing, 100～300nm, on surface of the BG granules be realized by metathetical reaction, which cover BG granules with HA microcrystals and make the covered BG granules taking position charges in absolute alcohol, sequentially realize the EPCD of the BG and HA granules on the cathode, so it is feasible to make a titanium alloy/BG/HA bioactive graded coating by making use of EPCD technology. The corrosion experiment of rich boron bioglass coating and plasma spray coating showed that split phase, rich boron and rich silicon phase, occurred during its preparation. In basic medium the corrosion behavior of 〓 BG coating showed uniformity corrosion, the corrosion mostly occurred at rich boron phase area, therefore batch formula design of BGshould avoid the occurring of split phase. The corrosion appearance of plasma spray coatingappeared a non-uniform corrosion, mostly occurred at the edge of the laminated HA moltendrops, and emerged an accelerated corrosion tendency, which will easyly lead to corrosioncrackles extending to the interface and the happening of osmotic interfacial corrosion, thatmay be one of the major reasons leading to the coating cracking-off in the later period. Thetesting results of thermal expansion coefficient of 〓 and 〓BG showed the thermalexpansion coefficient of 〓 BG matched with that of titanium alloy better, and 〓 BG couldsinter with titanium alloy into densification enamel layer at low temperature (720℃).

将Ti6Al4V合金在1000℃下进行真空热处理会降低其力学性能，且合金内的V元素会向表面富集，因此，钛合金真空热处理和表面涂层的烧结温度不能过高，即应低于其相转变点；通过对生物活性梯度涂层的组成和结构的设计，分析和计算了梯度涂层内的应力大小和分布，结果表明：对于本研究，当成分分布系数n=1.5时，可以获得较合理的涂层力学性能，即在沉积开始时，采用富含BG颗粒的悬浮液，以便在钛合金侧获得同底层BG有良好过渡的富BG涂层；梯度涂层界面和表面的应力大小、性质由材料组成本身的性质决定，改变成分分布系数，只能改变涂层内应力变化的趋势；涂层的厚薄不影响涂层内的应力分布规律，但涂层越薄，涂层内的应力变化越快，但这并不意味着涂层越厚越好，因为涂层越厚，涂层允许的变形越小，对于应用于弯曲受力部位的涂层而言，涂层应薄一点为好(50μm)；而对于仅纯受剪切应力的部位，如牙根种植体，涂层可适当加厚(80～100μm)；通过对HA和BG颗粒在水溶液体系和非水溶液体系中的带电特性和电泳沉积的研究发现，它们在水溶液体系中很难发生电沉积；在无水乙醇溶液中，HA颗粒带正电，可在阴极钛合金片上发生均匀的电泳沉积，而BG颗粒则带负电荷；利用复分解反应法，可以制得100～300nm的HA，通过诱导HA在BG颗粒表面结晶，可对BG颗粒进行表面包覆，获得了被HA包覆的BG颗粒，改变了BG颗粒表面的带电特性，使BG和HA颗粒在无水乙醇中均带上正电荷，从而实现了HA和BG颗粒在阴极上的共沉积。

Results Extensive and diffuse synovial hyperplasia can be seen in patients with RA;synovial pannus formation can be seen in 25 cases.

结果RA组病人均可见广泛、弥漫的滑膜增生，其中25例病人可见滑膜血管翳形成，而OA组仅7例病人可见轻度滑膜增厚，未见滑膜血管翳形成者(X2=55.78P.005)；RA组关节软骨及软骨下骨改变较严重且弥漫，而OA组软骨退变则较局限，且以关节摩擦大的部位受损为著，其软骨下骨改变较为局限，常常见于IV软骨退变；关节腔积液、半月板及韧带改变，在OA组与RA组之间无差异。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。