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Methods:The 13 cases of congenital pulmonary agenesis and hypoplasia were veritfied by bronchcscopy and operation or pathology the characteristics of the X-ray,CT and bronchography were analysed.

对13例先天性肺不发育和发育不良经支气管镜检、手术或病理证实的X线平片、CT扫描、支气管造影分析其影像学表现。

Objective:To observe the difference of pulmonary function and bronchodilatation test of the cases with asthmatic patients in their alleviative period.

目的:观察支气管哮喘缓解期老年及青年患者的肺通气功能、支气管舒张试验有何异同。

Methods:Analyzing the result of 36 cases with senile asthma group, that were in their alleviative period, 28 cases in the adolescent age that suffered asthma in their alleviative period.

对处于支气管哮喘缓解期的老年患者36例,青年患者28例,进行肺通气功能、支气管舒张试验测定并比较分析。

Results: In the senile asthmatic patients during their alleviative period, 91.67% had abnormal pulmonary function and 58.33% had positive reaction in bronchodilatation test.

结果:支气管哮喘缓解期老年患者的肺通气功能异常率达91.67%,青年患者只有57.14%;支气管舒张试验测定老年患者阳性率为58.33%,青年患者达92.86%。

Results 6 patients with PAP presented with ground-glass opacification of the bilateral lungs on HRCT. Typical chest HRCT scan showed "map-like" lesions in 3 cases and "cobble stone-like" lesions in 3 cases. Multifocal consolidative opacities in the lungs were seen on HRCT in 3 cases. Lung biopsies from 6 patients with PAP revealed a prominent positive periodic acid-Schiff intra-alveolar exudates. There were normal alveolar spetasis in 3 patients while interstitial thickening, fibroblast hyperplasia, interstitial fibrosis in the others.

结果 6例患者在不同层面可见磨玻璃影,其中2例可见小结节影;3例表现为两肺斑片状磨玻璃影与周围肺组织分界清楚,呈地图样改变;3例因磨玻璃影与小叶间隔增厚交织成铺路石样改变;3例可见肺泡实变融合成密度较高的斑片状阴影,1例在肺泡实变区可见&空气支气管征&。6例患者活检肺组织在光镜下显示肺泡腔内充满大量块状或颗粒状嗜伊红物质,PAS染色阳性,AB染色阴性,其中3例肺泡间隔正常,3例肺泡间隔增宽,可见慢性炎性细胞浸润、成纤维细胞增生和胶原沉积。

In this group,16 cases were involved in central pulmonary arteries (66.7%) and 4 cases with dilated bronchial arteries (17%),9 cases with pulmonary infraction (37.5%) whose pulmonary embolismic index was ranged from 24% to 83%, other 15 cases with no pulmonary infraction whose embolismic index was ranged from 5% to 61%,and there were significant difference between the two groups.

中央肺动脉受累16例,占66.7%(16/24),支气管动脉扩张4例,占16.7%(4/24),发生肺梗死9例,占37.5%(9/24)。9例发生肺梗死的肺动脉栓塞指数24%~83%(平均46.5%),15例非肺梗死的肺动脉栓塞指数5%~61%(平均21%),两组栓塞指数具有显著差异性。

Objective: To measure the variation and significance of respiratory impedance and pulmonary ventilation function in patients with bronchial asthma by impulse oscillometry before or after the bronchial provocation test, investigate the relationship between the IOS method and bronchial provocation test, and evaluate the clinical significance in bronchial asthma by IOS method.

目的:应用脉冲振荡法测定支气管哮喘患者在支气管激发试验前后的呼吸阻抗及肺通气功能参数的变化规律和临床意义,探讨IOS测定方法能否作为支气管激发试验的判断方法以及IOS测定参数在哮喘诊断中的价值。

Results:The following phenomena were observed:the Ph, PaO2 of the model rabbits descended sharply, the PaCO2 increased lightly, the HR slowed down obviously, but the BR increased, the SBP and DBP of the model rabbits descended markedly, and the PS content decreased dramatically. The pneumonic pathology changes showed pneumorrhagia, atelectasis, shrink of alveolus and pulmonary hyaline membrane. The above results indicated that it accorded with the standard of I-type of acute respiratory distress syndrome.

结果:整肺灌洗后模型兔的血气pH、PaO2急剧下降,PaCO2 轻度上升,心率明显减慢而呼吸频率增加,SBP和DBP均明显下降;支气管肺泡灌洗液中PS含量明显下降;病理检查提示出现肺出血、肺不张、肺泡萎缩、透明膜形成等病变,符合Ⅰ型重症呼吸衰竭临床诊断标准。

The biochemical composition and the surface activities of pulmonary surfactant were determined in tracheal aspirates from 15 neonates, and bronchcalveolar lavage fluid from 13 rabbits with pulmonary hemorrhage.

作者等测定15例新生儿肺出血气道吸出物和13只兔肺出血模型支气管肺泡灌洗液中肺表面活性物质的生化成分和表面活性。

The rabbit model of lung contusion was used to measure the changes in various physical parameters and inflammatory mediators such as C3a, C5a, IL-8 in bronchoalveolar lavage fluids of the contused lung.

利用家 兔肺挫伤模型,测定治疗前、后挫伤肺各项物理指标及挫伤肺局部支气管肺泡灌洗液中炎性介质 C3a、C5a、白细胸介素8(IL-8)的变化。

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