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Objective: To analyze CT and pathological features of bronchopulmonary carcinoid and to explore the pathological foundation of its CT manifestations.

目的:分析原发性支气管肺类癌的CT表现并与病理改变进行对照,了解各种CT征象的病理基础,提高对该病的诊断水平。

Earlier results of this study showed that low-dose hydrocortisone reduced mortality and bronchopulmonary dysplasia in ELBW infants exposed to chorioamnionitis.

该研究的早期结果显示,小剂量氢化可的松降低暴露于绒毛羊膜炎的ELBW婴儿的死亡率和支气管肺发育不良发生率。

Methods in the past 5 years, we have diagnosed 61 cases COPD and bronchiectasis, these patients'clinical manifestations, X-ray and computed tomography of chest, pulmonary spirometry were analysed.

回顾性分析本院5年来诊断的61例慢性阻塞性肺病合并支气管扩张的患者的临床表现、影像学特点、肺功能特点。

Either of two main branches of the trachea, leading directly to the lungs.

支气管气管的两个主要分支的任一支,直接通向肺

"Arborize: To have or produce branching formations, as the bronchial tubes of the lungs."

使成树状:具有或产生有分支的结构,如肺的支气管

Results The cases of this study account for 5.2%(184/3534) of primary bronchiogenic carcinomas and 14.5%(184/1265) of pulmonary adenocarcinomas that were admitted by PUMCH during the same period. The ratio of males to females is 1:1.24. 27.2% of the cases were discovered during health checkups, with no obvious symptoms. Because of its radiological features, BAC could easily be misdiagnosed as pneumonia, pulmonary tuberculosis or interstitial lung disease, and the ratio of the misdiagnosed cases is as high as 41.9%.

结果 本组病例占我院同期原发性支气管肺癌的 5.2 ( 184/3534 ),占我院同期肺腺癌的 14.5%( 184/1265 ),男女之比 1:1.2 ,无症状体检发现者占 27.2%, BAC 影像学的表现易被误诊为肺炎、肺结核、间质性肺病,误诊比例高达 41.9%,综合治疗的疗效较单一治疗效果好。

Results showed:(1) The airway responsiveness of smoke control group was higher than that of normal control group, the airway responsiveness of smoke + exercise group was lower than that of smoke control group;(2) Plasma level of cortisol determined immediately after exercise was higher than that determined before exercise, no significant difference occurs between that determined next day morning after all exercise finished in contrast to that determined before exercise;(3) HE staining showed, there was severe chronic pulmonary inflammatory response in smoke control group, which was reduced in the smoke + exercise group;(4) chronic cigarette smoke downregulated the protein and mRNA expression of BKca in smooth muscles of bronchi and bronchioli, exercise increased the mRNA expression of BKca;(5) chronic cigarette smoke downregulated the protein and mRNA expression of Kv1. 5 in smooth muscles of bronchi and bronchioli, exercise increased both the protein and mRNA expression of Kv1. 5 in contrast to smoke control group in bronchioli and did not effect the expression of Kv1. 5 in bronchi;(6) chronic cigarette smoke induced upregulation of FIZZ1/RELMα in bronchial smooth muscle cells, exercise decreased these effect.

结果:(1)吸烟对照组的气道反应性明显增高,吸烟加运动应激可明显降低大鼠的气道反应性;(2)吸烟运动组运动后血浆皮质醇浓度明显高于运动前,但全部运动结束后次日晨测定的血浆皮质醇浓度与运动前无明显差异;(3)HE染色显示,吸烟对照组肺组织出现明显的慢性炎症反应,吸烟加运动应激组比吸烟对照组炎症反应轻;(4)慢性吸烟可降低大鼠大气道和小气道BKca mRNA和蛋白表达,而吸烟加运动应激可使BKca mRNA表达上调,但对小气道的蛋白表达无影响;(5)慢性吸烟可降低大鼠大气道和小气道Kv1.5蛋白和mRNA表达,在小气道吸烟加运动应激可减轻这种作用,大气道则无作用;(6)吸烟使支气管平滑肌的FIZZ1/RELMα蛋白表达明显增强,而吸烟加运动组的RELMα蛋白及mRNA均明显减弱。

The consolidation and ill-defining diffuse nodule appeared in 8 cases, air bronchogram in 11 cases, bulging of the interlobar fissure in 4 cases,heterogeneous consolidation in 7 cases, cystic airspaces in 6 cases, and the CT angiogram sign in 2 cases, the consolidation were peripherally distributed in 15 out of 18 cases.

结果:18例肺炎型肺癌影像学表现两肺多发性分布7例,叶性分布8例,段性分布3例,所有病例均有实变存在,外周分布的15例,伴有不规则小结节的为8例,空气支气管征的11例,叶间裂向外突出的4例,实变影不均匀分布7例,不规则小囊腔6例,CT血管征2例。

Results After 2 or 6 hours of LPS intravenous administration, severe lung injury and positive signals of NT occurred with the latter located in the pulmonary macrophages, endothelia, subendothelial and muscular layers of the pulmonary artery.

结果 LPS静脉注射2 h和6 h 后,肺脏有明显损伤及硝基酪氨酸产生的阳性信号,该信号主要分布于肺泡壁巨噬细胞、肺小血管和细小支气管周围的巨噬细胞以及部分肺动脉的内皮细胞、内皮下层及肌层。

BE1 monoclonal antibody can be used to detect basophils in tissue.

BB1单克隆抗体可有效地用于支气管肺组织标本的嗜碱性粒细胞免疫组织化学检测,同时急性发作的致死性哮喘患者气道中嗜碱性粒细胞明显增加,可能与哮喘病情恶化、甚至死亡有关,而非致死性的慢性哮喘患者气道中嗜碱性粒细胞与对照组无异,说明嗜碱性粒细胞可能主要参与哮喘的急性病程。

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