支气管的

Rarely, the patient may experience significant changes in temperature, allergic reactions to drugs, damage to teeth due to the breathing tubes being placed in the trachea, bleeding problems, bronchospasm in the lungs, aspiration of stomach contents, or injury to nerves when nerve blocks are used.

很少见的情况下，病人会有体温的重要改变，对药物的过敏反应，气管导管置入导致的牙齿损坏，出血的问题，肺部的支气管痉挛，胃内容物的吸入，实施神经阻滞时的神经损伤。

With the help of Axioplan 2 imaging system, we quantified the change of expression of ICAM-1, MUC5AC, goblet cell and NF-κB. Analyze the results by SAS method. Results (1) Grouped by index of lung function, the expression of ICAM-1 at the level of gene and protein had increased significantly in the epithelial cells of patients with COPD, compared with group of normal lung function.

取病灶远端的正常叶段支气管组织制备石蜡切片，原位杂交检测气道上皮中ICAM-1的mRNA的表达量；免疫组化检测气道上皮中ICAM-1和MUC5AC的蛋白表达变化；AB/PAS特殊染色法检测患者气道上皮细胞中杯状细胞的含量；PCR扩增法检测原代培养的气道上皮中MUC5AC的基因表达量和NF-κB的变化。

objective to discuss perioperative complication and management of patient with high risk copd following esophagectomy.methods 45 patients with high risk copd underwent esophagectomy with epidural block combined with general anesthesia.perioperative treatment included smoking cessation,chest physiotherapy,prevention and control of infection of air way and appropriate bronchodilators of air way,breathing exercises,nutrition support and oxygen therapy.painkiller was instilled after surgery,early exercises,ensuring unobstruction of the air way,mechanical ventilation was applied when needed.results 3 had hypoxaemia in operation.after surgery,all patients had spo2 somewhat declined.6 had lung infection.6 were removed of bronchial secretion by bronchoscope.2 were supported by ventilator by using intubation.2 underwent tracheotomy.1 had disturbances of acid base balance and treated by using hydrochloric acid muriatic acid.all patients recovered rather smoothly and discharged from hospital.conclusion high risk copd is not the absolute contraindication of esophagectomy.active management before and after surgery ensures the safety and recovery of patients.

目的 探讨重度慢性阻塞性肺疾病简称慢阻肺病人食管切除术围手术期常见并发症及其处理。方法 45例重度慢阻肺的病人在全麻联合硬膜外阻滞下进行开胸食管切除手术，围手术期处理包括术前戒烟、胸部理疗、预防和控制呼吸道感染、解痉化痰、呼吸功能锻炼、营养支持和氧疗；术后硬膜外镇痛、早期锻炼、保持呼吸道通畅，部分病人予以呼吸支持。结果术中3例出现低氧血症。术后所有病人pao2均有不同程度的下降，6例出现肺部感染，6例行纤维支气管镜吸痰，2例通过气管插管给予呼吸机支持，2例行气管切开术，1例酸碱平衡紊乱使用盐酸精氨酸治疗。所有病人均痊愈出院。结论重度慢阻肺病人并非开胸食管切除手术的绝对禁忌证，积极的术前准备和严格的术后管理可减少和控制术后急性发作，有助于确保此类病人的围手术期安全和康复。

The four-week twice immunized hamsters acquired anti-MP in-fection capacity in local respiratory tract,as a result that swab culuturepositise was belove that of unimmunization group,and that only onehumster's lavage fluid culture was positive in immunization group.How-ever,unimmunization group positive rate of swabs and lavage fluid cul-ture was very high.This hinted that local respiratory tract's anti-MPinfection capacity was weak at the primary infection and the ability de-veloped gradually.4.The sIgA change in broncheal-lung lavage fluid.

而未免疫组咽拭子和支气管肺泡灌洗液MP分离培养的阳性均很高，说明在初次感染时，呼吸道局部防御清除MP的作用差，但随着时间的推移，其灌洗液培养的周次阳性率有下降趋势，MP培养的滴度亦随之降低，说明在感染以后随着时间的推移，呼吸道局部逐渐产生了防御、清除MP感染的作用。

Results showed:(1) The airway responsiveness of smoke control group was higher than that of normal control group, the airway responsiveness of smoke + exercise group was lower than that of smoke control group;(2) Plasma level of cortisol determined immediately after exercise was higher than that determined before exercise, no significant difference occurs between that determined next day morning after all exercise finished in contrast to that determined before exercise;(3) HE staining showed, there was severe chronic pulmonary inflammatory response in smoke control group, which was reduced in the smoke + exercise group;(4) chronic cigarette smoke downregulated the protein and mRNA expression of BKca in smooth muscles of bronchi and bronchioli, exercise increased the mRNA expression of BKca;(5) chronic cigarette smoke downregulated the protein and mRNA expression of Kv1. 5 in smooth muscles of bronchi and bronchioli, exercise increased both the protein and mRNA expression of Kv1. 5 in contrast to smoke control group in bronchioli and did not effect the expression of Kv1. 5 in bronchi;(6) chronic cigarette smoke induced upregulation of FIZZ1/RELMα in bronchial smooth muscle cells, exercise decreased these effect.

结果：(1)吸烟对照组的气道反应性明显增高，吸烟加运动应激可明显降低大鼠的气道反应性；(2)吸烟运动组运动后血浆皮质醇浓度明显高于运动前，但全部运动结束后次日晨测定的血浆皮质醇浓度与运动前无明显差异；(3)HE染色显示，吸烟对照组肺组织出现明显的慢性炎症反应，吸烟加运动应激组比吸烟对照组炎症反应轻；(4)慢性吸烟可降低大鼠大气道和小气道BKca mRNA和蛋白表达，而吸烟加运动应激可使BKca mRNA表达上调，但对小气道的蛋白表达无影响；(5)慢性吸烟可降低大鼠大气道和小气道Kv1.5蛋白和mRNA表达，在小气道吸烟加运动应激可减轻这种作用，大气道则无作用；(6)吸烟使支气管平滑肌的FIZZ1/RELMα蛋白表达明显增强，而吸烟加运动组的RELMα蛋白及mRNA均明显减弱。

Bronchiolitis obliterans is the most disturbing complication following lung transplantation. This study is to investigate whether prolonged ischemia would promote early establishment of BO Material and Methods Left lower lobectomy was performed from miniature swine. Lung fragments, each measured 1 cm3, contained terminal bronchioles were auto- or alloimplanted into the subcutaneous area around the nipples. These lung implants were removed on 7th; 14 th; 21 th; 28th and 56th days and were fixed for histological examination. Experimental group using the same procedures but the left lower lobe was washed with 4.degree.C Lactate ringer via interlobar artery before lobar bronchus was resected.

肺移植后的阻塞性细支气管炎是肺移植后最困扰的并发症，本研究的目的希望了解缺血时间的延长是否会促进阻塞性细支气管炎提早发生实验方法施行小猪的左下肺叶切除手术，将取下的肺切成含终末支气管1 公分立方的肺小块，以自体及异体异位肺移植模式，将植入小猪皮下的肺小块於植入后第7、14、21、28 及56 天取下，在病理下检示其病理变化，并利用原位灌留的方式将左下肺叶以4℃林格氏液灌洗后再摘除之，观察有无灌洗对於阻塞性细支气管炎生成的影响。

The outcomemeasures used to assess lung injury included: the change inweight gain and ultrafiltration coefficient, the frequency ofvascular failure, the histological lesions and the concentrationof tumor necrosis factor- and malondialdehyde in the bronchoalveolarlavage fluid.

评估肺损伤程度的项目包括：重量增加和超滤系数的改变，血管功能衰竭的频率，组织学病变及肿瘤坏死因子的浓度和支气管肺泡灌洗液中的丙二醛的量。

DESIGN: In a population based birth cohort, the Avon Longitudinal Study of Parents and Children, we related dietary patterns in pregnancy, previously identified using principal components analysis ('health conscious', 'traditional', 'processed', 'vegetarian', and 'confectionery'), to: early wheezing phenotypes and eczema; wheezing, hayfever, eczema, doctor-diagnosed asthma, atopy and total IgE at 7 years; lung function and bronchial responsiveness at 8-9 years.

试验设计：在一项基于出生的队列研究（Avon双亲与儿童的纵向研究， ALSPAC）中，通过主成分分析（健康意识；传统饮食；食物加工；素食；糕点），研究怀孕母亲的膳食结构与喘息早期表型和湿疹；喘息、枯草热、湿疹、医生诊断的哮喘、7岁时特应性和总IgE水平；8－9岁时的肺功能和支气管反应性之间的关系。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。