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Methods: This research based on the viewpoints of three theories, namely, the combination of exopathogens and inpathogens, coldness of body and drinking cold tends to impair lung, and overstrain leading to consumption of qi, combining with asthmatic nosogenesis of modern medicine.

依据"外内合邪"、"形寒饮冷则伤肺"、"劳则气耗"等观点,结合现代医学支气管哮喘致病原理,在冬季寒冷环境中,以冰水及寒性饮食饲养大鼠,配以冰水游泳,卵蛋白致敏的方法,建立支气管哮喘病寒饮蕴肺证大鼠模型。

It were found by comprehensive analysis, the precisive diagnosis rates of the markers from bronchoalveolar lavage fluid were much higher than that from blood, and the markers from alveolar macrophage were much higher than that from broncholaveolar lavage fluid. The precisive diagnosis rates of fibronectin secreted by alveolar macrophage, and fibronectin secreted by alveolar macrophage inhibited by cort and inhibitory rate were 96. 2%, 92. 3%, and 92. 3%, with the diagnosis markers of higher sensibitity and specificity.

综合分析发现,支气管肺灌洗液中指标的正确诊断率高于外周血,而肺泡巨噬细胞中诊断指标又优于支气管肺灌洗液,其中肺泡巨噬细胞产生的纤维结合蛋白、皮质激素抑制肺泡巨噬细胞产生纤维结合蛋白和纤维结合蛋白抑制率均为敏感性和特异性较高的诊断指标,其正确诊断率分别为96.2%、92.3%和92.3%。

Results The segmental bronchial ramifications of the left upper lobe were classified into three types mainly: common stem of apical and posterior segmental bronchi (64%, 130/200), trifurcation (23%,45/200), common stem of apical and anterior segmental bronchi (10%, 21/200), and they could be identified in two typical slices of transverse thin-section CT.

左肺上叶3种主要分支类型可以通过薄层CT横断面图像2个典型层面辨认;左肺下叶依据基底干支气管分支的不同分为2种主要类型,Ⅰ型163例(75%):基底干支气管两分支,即内前底段支气管、外后底段支气管;Ⅱ型39例(18%):基底干支气管3分支,即内前底段、外侧底段、后底段支气管。

The consolidation and ill-defining diffuse nodule appeared in 8 cases, air bronchogram in 11 cases, bulging of the interlobar fissure in 4 cases,heterogeneous consolidation in 7 cases, cystic airspaces in 6 cases, and the CT angiogram sign in 2 cases, the consolidation were peripherally distributed in 15 out of 18 cases.

结果:18例肺炎型肺癌影像学表现两肺多发性分布7例,叶性分布8例,段性分布3例,所有病例均有实变存在,外周分布的15例,伴有不规则小结节的为8例,空气支气管征的11例,叶间裂向外突出的4例,实变影不均匀分布7例,不规则小囊腔6例,CT血管征2例。

Imaging finding of pneumonic-type bronchioloalveolar carcinoma shows a peripheral consolidation, air bronchogram, bulging of the interlobar fissure, CT angiogram,cystic airspaces and so on.

肺炎型肺癌表现为典型的外周分布,空气支气管征、不规则小结节、叶间裂外突、多发小囊腔样改变等,但与感染性肺炎很难区分。

The intersegmental veins can be considered as the main tributary of pulmonary segmental veins and it commonlly located in the inferior, interior and posterior side of the corresponding segmental bronchi.

肺段动脉与支气管紧密伴行,并有基本一致的分支和分布,多位于支气管的上、外或前方;肺段静脉不与支气管分支一致,可分段内支与段间支,后者可视为肺段静脉的主干,多位于肺段支气管的下、内或后方。

OBJECTIVE The aims of this study are to observe the effect and acute side-effects of 192-Iridium high dose rate intrabronchial brachytherapy combined with bronchial artery infusion chemotherapy and radiotherapy on non-small cell lung cancer, and also to assess the clinical value of the treatment of HDR-IBB combined with BAI and RT, and to explore a new method of combined treatment for inoperable non-small cell lung cancer MATERIALS AND METHODS Between May 1998 and Octob...

中文摘要:一、目的:本课题观察了~(192)Ir高剂量率支气管腔内放疗对支气管动脉灌注化疗和外照射治疗非小细胞肺癌疗效的影响和副作用,初步研究探讨联合治疗的临床价值,目的在于为不能手术或不愿手术的局部中晚期非小细胞肺癌患者,探索一种新的综合治疗方法。

The management for extralobar pulmonary sequestration and bronchogenic cyst located at the extrathorax and mediastinum was simple resection. For congenital adenomatoid malformation, intrapulmonary bronchogenic cyst and intralobar pulmonary sequestration, total lobectomy was done. All the 10 patients are living well now, after from 6 months to 7 years of follow-up.

手术方式为对胸腔外及纵隔腔的支气管囊肿和肺叶外的肺隔离囊肿採取简单切除术;对先天性腺瘤状畸形、肺內支气管囊肿和肺叶內的肺隔离囊肿採取肺叶切除。10例经电话追踪,从6个月至7年不等,其发育、运动均与正常儿童无异。

Resujts:① The distribution of lesions are mostly symmetrical, extensive, predominant in the middle and lower lung fields, and posterior areas in peripheral;② There are so many HRCT findings of lung, ILD is predominant: intralobular interstitial thickening 46 cases (100%), ground-glass opacity 41 cases (89.13%), peribronchovascular or centrilobular interstitial thickening 40 cases (86.96%), interlobular septal thickening 38 cases (82.61%), irregular linear opacity 37 cases (80.43%), small nodular opacity 34 cases (73.91%), subpleural line 27 cases (58.70%), bmnchiectasis or bronchiolectasis 19 cases (41.30%), patch opacity 18 cases (39.13%), expiratory mosaic sign 15 cases (32.61%), interface sign 14 cases (30.43%), honeycombing 12 cases (26.09%), emphysema or bulla 3 cases, cystic airspace suspected 1 case, and atelectasis suspected 1 case;③ Mediastinum and pleura: multiple small lymphonodi in mediastinum 41 cases (89.13%), pleural thickening or rough 38 cases (82.61%), esophagoectasis 11 cases (23.91%), unilateral little pleural fluid 1 case, and mediastinal emphysema 1 case.

结果:①皮肌炎肺部病变分布呈对称、广泛、偏中下、偏外后的特点;②肺部HRCT表现多样,以肺间质性改变为主:小叶内间质增厚46例(100%),磨玻璃影41例(89.13%),支气管血管束增宽或小叶核心增大40例(86.96%),小叶间隔增厚38例(82.61%),不规则纤维索条影37例(80.43%),结节影34例(73.91%),胸膜下线27例(58.70%),支气管或细支气管扩张19例(41.30%),斑片影18例(39.13%),呼气相马赛克征15例(32.61%),界面征14例(30.43%),蜂窝影12例(26.09%),肺气肿或肺大泡3例,单纯囊状气腔1例,肺不张l例;③纵隔及胸膜:纵隔小淋巴结影41例(89.13%),胸膜增厚或毛糙38例(82.61%),食管扩张11例(23.91%),单侧少量性胸腔积液1例,纵隔气肿1例。

Drug intervention groups received either daily inhalation of budesonide, ipratropine or heparin respectively, starting on the 8th day or TGF-β1 monoclonal antibody(TB21)0.5 mg twice (6th and 19th day) via the tail veinous injection.

其它各药物干预组于制作模型第8 d起分别雾化吸入布地奈德(布地奈德组,12只)、溴化异丙托品(溴化异丙托品组,12只)和肝素(肝素组,6只)溶液。4周后检测小支气管平滑肌及胶原厚度,用免疫组化法及原位杂交法观察各生长因子在支气管肺内的表达,用放免法检测血清和BALF中细胞外基质成分Ⅲ型前胶原、层粘连蛋白及透明质酸。

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The split between the two groups can hardly be papered over.

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