支气管哮喘

In experimental study,we choose healthy Wistar mice to make models of bronchial asthma in catabasis,we observe the influence on inflammatory factor and immunological factor in air-way、bronchial and pulmonary pathology after drench.

实验研究选择健康Wistar大鼠制作哮喘缓解期模型，观察防哮合剂灌胃后对气道炎性因子、免疫因子及支气管和肺脏病理学的影响，并与酮替芬阳性对照组比较。

In experimental study, we choose healthy Wistar mice to make models of bronchial asthma in catabasis, we observe the influence on inflammatory factor in air-way、bronchial and pulmonary pathology after drench concentrated solution of FXG.

实验研究选择健康Wistar大鼠制作哮喘缓解期模型，观察防哮颗粒浓缩液灌胃后对气道慢性炎症及支气管和肺脏病理学的影响，并与酮替芬阳性对照组比较。

Healthy Wistar Rats were chosed to make models of remission stage of asthma,the influence on inflammatory factor and immunological factor in air-way、bronchial and pulmonary pathology after treating with Fang Xiao Mixture were observed,and compared with ketotifen group.

选择健康Wistar大鼠制作哮喘缓解期模型，观察防哮颗粒对模型大鼠气道炎性因子、免疫因子及支气管和肺脏病理学的影响，并与酮替芬阳性对照组比较。

Ping chuan-fang prescription is carefully composed accordingly. The clinical investigation shows that PCHF can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously improve the pulmonary function of the patient. The animal experiment showed that PCHF can prolong the asthmatic time and low the concentration of WBC, EOS, IL-4, ET-1 in the blood and BALF. It can restrain the collection of EOS in the lung and relieve the inflammation caused by EOS. It also can cut down the secretion of the respiratory air-way and relieve the obstruction of it.

动物实验表明：平喘方能明显延长卵蛋白造模大鼠的引喘潜伏期，且与氨茶碱对照有非常显著性差异(P＜0.01)；能降低哮喘模型大鼠血浆及肺泡灌洗液中白细胞、嗜酸性粒细胞及IL-4、ET-1的含量；能抑制肺局部EOS的聚集，明显减轻由EOS浸润引起的慢性变应性炎症反应；能减少气道分泌物，减轻细支气管及小血管管壁的增厚，减轻周围组织的水肿，从而减轻气道的阻塞，最终改善肺通气，缓解喘息症状。

Ping chuan-fang prescription is carefully composed accordingly. The clinical investigation shows that PCHF can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviouslycan not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously improve the pulmonary function of the patient. The animal experiment showed that PCHF can prolong the asthmatic time and low the concentration of WBC, EOS, IL-4, ET-1 in the blood and BALF. It can restrain the collection of EOS in the lung and relieve the inflammation caused by EOS. It also can cut down the secretion of the respiratory air-way and relieve the obstruction of it.

动物实验表明：平喘方能明显延长卵蛋白造模大鼠的引喘潜伏期，且与氨茶碱对照有非常显著性差异(P＜0.01)；能降低哮喘模型大鼠血浆及肺泡灌洗液中白细胞、嗜酸性粒细胞及IL-4、ET-1的含量；能抑制肺局部EOS的聚集，明显减轻由EOS浸润引起的慢性变应性炎症反应；能减少气道分泌物，减轻细支气管及小血管管壁的增厚，减轻周围组织的水肿，从而减轻气道的阻塞，最终改善肺通气，缓解喘息症状。

FXG can reduce the content of inflammatory factor TNF-αand immunological factor IgE in the serum of bronchial asthma children in catabasis, restrain the collection of EOS in bronchi and lung, restrain the inflammation in air-way and alleviate air-way straitness;improve the level of serum IgA、IgG、IgM and CD3、CD8,enhancing the immune functiong of bronchial asthma children.

结果：防哮颗粒的总有效率为93.33%，在减轻患儿主要症状、体征，减少感冒次数、咳喘天数，改善肺循环方面优于两对照组；在改善肺功能方面与普米克都保的疗效无差别，而明显优于固本咳喘片(P.01)；并能降低哮喘缓解期儿童血清中炎性因子TNF-α、免疫因子IgE的含量，抑制支气管和肺脏局部EOS聚集，抑制气道变应性反应，减轻气道狭窄；提高IgA、IgG、IgM水平及CD3、CD8含量，增强患儿免疫力。

The outpouring of mucus from hypertrophied bronchial submucosal glands, the bronchoconstriction , and dehydration all contribute to the formation of mucus plugs that can block airways in asthmatic patients.

支气管黏膜下层的腺体肥大分泌黏液，支气管壁的破坏和脱水均有助于黏液栓的形成并阻塞哮喘病人的气道。

We conclude that SI can be performed safely following exercise challenge in asthmatics with EIB, and that the seerity of EIB prior to SI is not a major determinant of bronchoconstriction during SI.

在运动支气管痉挛性哮喘患者运动激发后进行SI是安全的，SI前EIB严重度并非SI时支气管痉挛主要决定因素。

We made HE dye and observe the pathological transformation of lung tissue under optical microscope. Result and Conclusion Pingchuan mixture could restrain the chronical nonspecial inflammation in airway.

结果及结论平喘合剂可抑制炎性细胞在肺及支气管局部的浸润，减轻肺脏、支气管的病理损伤，通过拮抗慢性非特异性气道炎症而发挥治疗哮喘的作用。

Abstract］ objective to study the effect of 654-2 on the treatment of bronchial pneumonia in children.methods 204 patients were chose and randomly divided into treatment group 654-2 plus conventional therapy） and control group,each group with 102 cases,then the effect of the two groups were compared.results the treatment group's time of pyretolysis,disappearance of asthma and pulmonary rales,x line inspection recover to normal,average days of hospitalization and other indexes were all significantly better than the control groupp.01）.conclusion 654-2 has a very significant effect on the treatment of bronchial pneumonia.

目的 探讨山莨菪碱（654-2）在小儿支气管肺炎中的疗效。方法选择204例患儿随机分为治疗组（654-2加传统疗法）和对照组各102例，进行治疗对比观察。结果治疗组退热时间、哮喘消失时间、肺部啰音消失时间、x线检查恢复正常时间、平均住院天数等指标均明显优于对照组p.01）。结论 654-2治疗支气管肺炎疗效非常显著。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。