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Month sheep (weight:2030 kg) were treated with localized papain instillations to generate heterogeneous emphysema, subsequently underwent BLVR using one?way flap device at subsegment.

通过CT确定靶区后,在X线造影定位并确定靶支气管后,经纤维支气管镜通过导丝和放送装置在肺气肿亚段放入1~2个单向活瓣支架,术后给予3 d抗炎治疗。

Abstract]objectiveto observe the effect of vagal block using ropivacaine on preventing the attack of bronchial asthma during thoracoscopy.

摘要]目的了解并发支气管哮喘的肺部病变病人胸腔镜手术中,用罗哌卡因阻滞迷走神经对预防支气管哮喘发作的效果。

Result There was no bronchopleural fistula、 tracheobronchial restenosis and death due to operation.

结果 术后效果良好,无支气管胸膜瘘、支气管再狭窄和手术发烧死亡。

Result There was no bronchopleural fistula 、 tracheobronchial restenosis and death due to operation.

结果 术后效果良好,无支气管胸膜瘘、支气管再狭窄和手术死亡。

Materials and methods: Twenty three patients with tracheobronchial TB underwent CT and tracheobronchial endoscopy.

材料与方法:23例气管支气管结核病人均做胸部CT和纤维支气管镜检查,分析其CT表现并与FOB所见对照。19例经组织学证实,4例经临床随访证实。

Drug intervention groups received either daily inhalation of budesonide, ipratropine or heparin respectively, starting on the 8th day or TGF-β1 monoclonal antibody(TB21)0.5 mg twice (6th and 19th day) via the tail veinous injection.

其它各药物干预组于制作模型第8 d起分别雾化吸入布地奈德(布地奈德组,12只)、溴化异丙托品(溴化异丙托品组,12只)和肝素(肝素组,6只)溶液。4周后检测小支气管平滑肌及胶原厚度,用免疫组化法及原位杂交法观察各生长因子在支气管肺内的表达,用放免法检测血清和BALF中细胞外基质成分Ⅲ型前胶原、层粘连蛋白及透明质酸。

Methods The samples were collected from 55 consecutive patients with tissue diagnosed lung cancers by fiberoptic bronchoscopic brushing. Mutation in coden 12 of H-ras oncogene was detected in the exfoliated cells using PCR-RFLP method (polymerase chain reaction-restriction fragment length polymorphisms).

对33例吸烟肺癌和22例不吸烟肺癌患者采用纤维支气管镜毛刷刷取支气管脱落细胞,应用PCR-RFLP方法进行H-ras基因突变检测。

Results: There were 14 cases of solitary bronchioloalveolar carcinoma, the distance of pleura to the centre of pulmonary node was smaller than 3.1cm, node diameter from 1.4cm to 3.5cm, the CT morphologic features of nodes were margin slick 2 cases, irregular margin 6 cases, short barb 5 cases, pleural retraction 11 cases, bronchogram 6 cases, vacuole 12 cases. 5 cases of consolidation bronchioloalveolar carcinoma, the main features were multisegment or lobes inflammatory consolidation, bronchogram phase 4 cases, and honeycomb 3 cases. 6 cases of diffused bronchioloalveolar carcinoma, the main features were widespread diffusion nodes, inequality of size, anisodistribute.

结果:孤立结节型14例,结节中心距胸膜均小于3.1cm,病灶直径为1.4~3.5cm,CT表现有边缘光滑2例,呈分叶征6例,短毛刺征5例,胸膜凹陷征11例,含气支气管征6例,空泡征12例;炎症型或实变型5例,病变呈多个肺段或肺叶的炎症样实变,见支气管气相4例,以及蜂房状含气腔3例;弥漫结节型6例,弥漫分布粟粒状与结节状致密影,大小不等,分布不均。

Objective: To observe the expression of GATA-3 in asthmatic mice lungs and to explore the feasibility of interleukin(IL-12) blockading GATA-3 expression in treatment of bronchial asthma.

目的:观察T细胞特异转录因子GATA-3在支气管哮喘小鼠肺部的表达,探讨应用白细胞介素12(IL-12)阻断GATA-3表达治疗支气管哮喘的可能性。

Objective:To observe the expression of GATA-3in asthmatic mice lungs and to explore the feasibility of in-terleukin(IL-12)blockading GATA-3expression in treatment of bronchial asthma.

目的观察T细胞特异转录因子GATA-3在支气管哮喘小鼠肺部的表达,探讨应用白细胞介素12(IL-12)阻断GATA-3表达治疗支气管哮喘的可能性。

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