提取剂

The total flavonoids content of peanut hulls of different sources were evidently different,those peanut hulls contained more total flavonoids from Shandong province,higher maturity and raw. This suggested that attention should be paid to the choice of peanut hulls as medicine materials. 3.The optimized extraction technology conditions considering the two indices of total flavonoids andβ-sitosterol were: the peanut hulls were extracted by 95% acohole 6 times of the hulls weight refluxing for 2 hours first,and extracted by 70% acohole 4 times of the hulls weight refluxing for 2 hours at the temperature below 80℃successionally,then the concentrate was dried vacuumizedly with the additament of starch 2% of the concentrate weight after the extracts were fitrated,united and concentrated. 4.The dried extract powder possessed high hygroscopy and low fluidity,but the weight variation of capsule contents could comply with the requirement of CP if it was mixed with dextrin and granulated by sieving 40 meshes using 95% ethanol as the wetting agent,and filled into capsules after dried below 60℃.The critical relative humidity of the granules was about 63%.

不同来源的花生壳总黄酮含量有较大差异，山东产区、成熟度高的及未经炒制的花生壳总黄酮含量较高，提示作为药材时应注意选择； 3、兼顾总黄酮及β-谷甾醇的最佳提取工艺为：先以95%乙醇6倍量加热回流提取2小时，再以70%乙醇4倍量80℃以下回流提取2小时，提取液过滤、合并、浓缩，加2%淀粉60℃以下减压干燥； 4、浸膏粉吸湿性大，流动性差，但加糊精并以95%乙醇为润湿剂、过40目筛制粒，60℃以下烘干后填充胶囊，可保证装量差异符合要求；颗粒临界相对湿度约为63%。

Wastewater containing titanium pigment was treated by microfiltration membrane, Nanometer titanium can be purified and concentrated by use of microfiltration. Operational conditions were optimized and the model was built. Finally, the amount of wash water was reduced. Based on the above research, the whole set equipment was designed, which can meet the needs in a titanium industry with a capability of 500 ton per year. Backflush and automatic control were used in the equipment, which has been steadily run two years, has been widely adopted in titanium industry. The technology has been widely adopted in titanium industry.In the recent years, whole set equipment of ceramic membrane was increasingly used in the recovery of desired production from fermentation broth in China. A new membrane process integrated with pretreatment of flocculation or coagulation was exploited to recover Inosine. ZrO2 ceramic membrane was used in the work, and the average permeation flux could reach 150L/m2.h under pH value of 3, transmembrane pressure 0.1MPa, CFV 3m/s, and temperature higher than 70C. The recovery ratio of inosine is higher than traditional recovery method, although inosine degraded under acidic and high temperature condition.

实验表明，ZrO_2膜处理肌苷发酵液的合适条件为pH=3、操作压力为0.1MPa、膜面流速3m／s、温度大于70度，此时可以获得平均渗透通量150L／m~2h，但由于酸性条件、高温下肌苷降解，导致肌苷收率有所降低，但仍高于传统肌苷提取方法得到的收率；为进一步提高肌苷得率，缩短提取工序，实验研究了絮凝剂预处理发酵液，解决碱性条件下由于蛋白析出导致膜污染加重的问题，研究表明采用CaCl_2絮凝并调节pH=11，可以获得平均渗透通量为180L／m~2h，肌苷得率大于95％；比较了三种肌苷提取工艺得到的产品质量，采用预处理与陶瓷南京工业大学博士学位论文膜分离结合的除杂工艺得到的粗昔质量与陶瓷膜分离、离子交换及活性炭吸附工艺生产的粗普质量相当，均优于传统的提取工艺；设计了每小时处理12一巧吨肌普发酵液的陶瓷膜成套装置，采用部分内循环的方式降低设备的能耗，简化了肌昔提取方式，提高了产品的收率和得率，由于减少离子交换和活性炭吸附，使得工厂废水排放量降低30一40%，降低酸、碱用量，有利于环境保护。

Adaptive decompressing status monitor based on MC68HC08;2. A new method was put forward for extracting the activity components in the plant by decompressing inner ebullition.

减压内部沸腾法是用少量低沸点解吸剂润湿被提取物料粉末，使其中的有效成分充分解吸，然后加入一定温度的热提取溶剂并迅速减压，使渗透到植物组织内部的解吸剂首先沸腾，强化提取过程。

The results showed as follows: 1 Extraction of gelsemium total alkaloids. Total alkaloids were extracted with 95 per cent ethanol. The extract rate was 0.519 per cent and the extract purity were 88.02 per cent and 87.38 per cent; Total alkaloids were extracted with chloroform .The extract rate was 0.416 per cent and the extract purity were 89.02 per cent and 94.52 per cent. 2 Isolation of gelsemium total alkaloids with TLC. Total alkaloids contained five or more alkaloids. The optimal developing agent was chloroform :methanol :ethyl acetate(9:l:0.3),the optimal eluent was methylene chloride:methanol(92:8). 3 Isolation of total alkaloids with column chromatography. Alkaloid A and alkaloid B were obtained, alkaloid B was identified as koumine.

研究结果如下：1、钩吻总碱的提取：用95％的乙醇提取钩吻生物碱提取率为0.519％，其提取物纯度为88.02％、87.35％；用氯仿提取钩吻生物碱提取率为0.416％，其提取物纯度为89.02％、94.52％。2、钩吻总碱的薄层层析分离：总碱中含有5种或5种已上的生物碱；氯仿：甲醇：乙酸乙酯(9：1：0.3)是最佳薄层层析的展开剂；二氯甲烷：甲醇(92：8)是柱层析的最佳洗脱剂。3、钩吻总碱的柱层析分离：共得到两种钩吻生物碱单体成分碱A和碱B，碱B为钩吻素子，碱A可能是钩吻素甲。4、钩吻总碱的急性毒性试验：钩吻总碱小鼠腹腔注射的半数致死量LD_(50是：7.38mg／kg，95％的可信限范围为：6.67mg／kg～7.94mg／kg。

Comparatively sundried flowers are more suitable to be extracted as an industrial material although the concrete yield of fresh flowers is a little more. At the same time the experiment process fully proves the selectivity of SFE-CO2. Low temperature and low pressure are suitable to extract concrete from natural flavor and fragrance;(2) The materials prepared to extract rutin are the flowers that are gotten rid of concrete by SFE-CO2. The extraction methods include the SFE-CO2 modified by alcohol, the method of hot alkali-precipitate with acid, and alkaly dissolving and acid subsiding combined with microwave or ultrasonic.

66%；产品运用GC-MS做了鉴定；虽然鲜花浸膏产率较高，但干槐花的物料状态更适合工业生产；同时实验过程充分体现了SFE-CO2的选择性，低温低压条件适合香料的SFE-CO2；(2)以超临界CO2(Supercritical CO2，简称SC-CO2)萃取过浸膏的干槐花为原料，运用夹带剂修饰的SFE-CO2、超声或微波或直接加热的碱溶酸沉法提取中药--芸香甙，相比之下，夹带剂修饰的SFE-CO2和超声辅助的碱溶酸沉法提取效果较好，芸香甙提取率分别为2。

Cationic resin was chosen to decolour the fermentation broth besides to play the role of cation exchange.

1选用732型阳离子树脂为丙酮酸发酵液的脱色剂和阳离子交换剂，把脱色和改性两道工序合并，简化了提取丙酮酸的环节，从而提高了丙酮酸的提取收率。

At present, the built factory area is more than 10000 m2, setting up modern preparation workshop and extraction workshop; owns nearly 80 sets of advanced equipments as vertical fluid drier, two dimensional movement melangeur, horizontal fluid drier and automatic capsule filling machine; owns production lines of 9 forms of drugs as tablet, capsule, granular formulation, syrup, oral liquid, bulk, tinctures, inuncts and raw material medicine (Rotundine, including pre-processing of TCM and extraction), with annual capacity of 5000 tons granular formulation, 500 million pills of tablet and 80 million pellets of capsule.

目前，建成的厂房面积达10000多平方米，设有现代化的制剂车间和提取车间；拥有立式沸腾干燥机、二维运动混合机、卧式沸腾干燥机、全自动胶囊填充机等各类先进制药设备近80套，拥有片剂、胶囊剂、颗粒剂、糖浆剂、口服液、散剂、酊剂、搽剂、原料药（罗通定、含中药前处理和提取）九个剂型的生产线，具备年生产颗粒剂5000吨、片剂5亿片、胶囊剂8000万粒等的生产能力。

The result indicates that the best method for extracting β-carotene is to saponify the test specimen one hour with 4% NaOH methyl alcohol solution in 60-70'c and then to separate with 3:7 acetone-benzine component solvent as extraction solvent, MgO as the absorbent, the acetone-benzine as the eluent. Extracted solvent has been determined in the color dish condition (1cm) by ultraviolet spectrophotometer at 447 nm. The result shows that the β-carotene in carrotis 0.134 mgg^(-1), 0.0863mgg^(-1) in red pepper and 0.0426 mgg^(-1) in spinach.

结果表明，比较优先的β-胡萝卜素提取方法是：试样用4% NaOH甲醇溶液在60℃~70℃皂化1h，用3：7的丙酮－石油醚混合溶剂提取，以Mgo为吸附剂，丙酮－石油醚为洗脱剂分离，提取液用紫外分光光度计在波长447nm，1cm比色皿条件下测定，得出蔬菜中β-胡萝卜素含量：胡萝卜为0.134mgg^(-1)，红椒为0.0863mgg^(-1)，菠菜为0.426mgg^(-1)。

An oncomelania killer is prepared through preparing mother liquid A from hydrochloric acid or 50 wettable powder of nicotinani line sul fate and dechlorinated water , preparing method liquid B from raw powder extracted from Huangqieguo fruit or bardabosnut seed and dechlorinated water , proportionally mixing them together and adding dechlorinated water for different concentrations .

灭钉螺剂及其生产方法，是将盐酸或硫酸烟酰苯胺50％可湿性粉剂加去氯水配成母液，再将由黄茄果果实提取的原粉或由麻风树籽提取的原粉加去氯水配成母液，将两母液按比例混合再加不同量的去氯水配成不同浓度的灭钉螺剂。

Objective To establish HPLC-UV method for determination of glycyrrhizin acid in compound nasal spray of glycyrrhizin and flower flos magnoliae,the chief active ingredient of formulation,glycyrrhizin acid,and to observethe therapeutic effect of this formulation on guinea pig's hypersensitive rhinitis.Methods A compound nasal spray formulation was prepared using extracts of glycyrrhizin and measured by HPLC-UV method.Mobile phase conˉsisted of methanol,0.2mol/L ammonium acetate and glacial acetic acid（67:33:1,v/v）,analytical column was Zorbax ODS C 18 and wavelength250nm.

目的 建立测定复方甘草和辛夷喷雾剂含量的方法并观察该制剂对豚鼠超敏性鼻炎的疗效方法以甘草提取的甘草甜素和辛夷花蒸馏提取液主药制备成鼻用喷雾剂，用反相高效液相色谱法测定制剂中甘草酸含量，检测波长为250nm，Zorbax ODS C 18 分析柱，流动相为甲醇：0.2mol/L醋酸铵：冰醋酸（67：33：1）。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失