控制元件

Cardiac toxicity was minimal in both groups, the editorial notes, adding that this is a major adverse effect of trastuzumab. However, the trialists point out that there was a bias, as they had selected women who had normal cardiac function after having received various other therapies (including anthracyclines and taxanes) as well as trastuzumab. Also, since the duration of observation was limited, the possibility of late events cannot be excluded."Nevertheless, the low incidence of adverse cardiac events is reassuring," they comment.

主编表示，两组之间发生心脏毒性的比例相似，且这是trastuzumab主要的副作用；然而，研究者指出其中有误差，因为他们挑选已经接受其它不同治疗（包括anthracyclines类药物与taxanes类药物）以及trastuzumab后心脏功能正常的病患；同时，因为试验观察时间长度有限，晚期发生不良反应的可能性并不能排除；他们的评论是，不管如何，心脏不良反应发生率低是可靠的。

He clowned you, dog.

他戏弄了你