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Nikolay did not go to Moscow, the countess did not renew her conversations with him about matrimony, and with grief, and sometimes with exasperation, saw symptoms of a growing attachment between her son and the portionless Sonya.

尼古拉没有到莫斯科去,伯爵夫人不再跟他谈到结婚的事情,她很忧愁地、有时愤恨地看见她儿子和没有嫁妆的索尼娅越来越接近的迹象。

It's basically a choice between a quickie approach and a strategic approach.

这个基础的抉择将决定你是快速地实现梦想还是有策略地接近它。

Health (although he's a bittougher than in NS1), being effective as a Skulk is all about knowingwhen and how to attack and being skilled enough to get close to

血量(虽然他已经比在ns1要硬一点),要有效率地做一只skulk就是要知道何时以及如何攻击以及要有技巧地接近

With China's rapid economic development, consumers are seeking higher quality of life, for natural and healthy products is increasing, and as a Tahitian Noni company in China to set up the first concept stores, so that consumers in a South Pacific-style environment, close to the feelings of Tahitian Noni products unique.

消费者正在寻求自然,健康的产品,更高的生活质量,越来越多,而作为大溪地诺丽公司在中国设立的第一个概念店,以便在南太平洋消费者式环境,接近大溪地诺丽产品独特的感情。

Both sides thought they could accept the peace proposal with dignity. 21. We believe that the younger generation will prove worthy of our trust. 22. He approached that "haunted house " with caution. 23. He was 75, but he carried his years lightly. 24. My guess is as good as yours. 25. The decision has to come. 26. If we lose our lives, then you'll lose yours! 27. If he had kept his temper, the negotiation would probably have been a success. 28. I have failed to convince him of his error. 29. The two teams tied. 30. Appearances are deceptive. 31. Her face had a strange, lost look. 32. I'm terribly sorry to have given you such a lot of trouble. 33. His answer is beside the mark. 34. Silence reigned all over for a while. 35. He said idly,"well, what does it matter?" Negation — affirmation 1. The doubt was still unsolved. 2. He carelessly glanced through the note. 3. He was an indecisive sort of person. 4. Hilter's undisguised effort to persecute the Jews met with worldwide condemnation. 5. It was said that someone had sown discord among them. 6. He manifested a strong dislike for business. 7. Don't lose time in posting this letter. 8. The examination left no doubt that some SK-II products contain excessive ingredients. 9. Students, with no exception, are to hand in their papers this afternoon. 10. Such flights couldn't long escape notice. 11. The significance of these incidents wasn't lost on us. 12. Don't unstring your shoes. 13. She said breathlessly… 14. He walked into the room noiselessly.

我们相信年轻一代不会辜负我们对他们的信任他小心翼翼的接近那幢"鬼屋"他已经75了,但日子依然轻松自在我和你预想的一样好我们必须作出决定了如果我们没命,你也别想活如果他当时控制一下他的情绪,这项谈判可能已经成功了我没能阻止他犯下错误外表并不可信她的表情奇怪而迷茫我很抱歉给你带来了这么多麻烦他答不对问一阵沉默他漫不经心地说"那么,那又怎么样呢"疑问依然没有消除他漫不经心的匆匆翻过那本笔记本他是个犹豫不决的人希特勒对于犹太人的大肆迫害遭到了全世界的谴责据说有人在他们之间挑拨离间他对谈生意表现出了极大的厌恶别忘了寄这封信这项实验无疑证明了SK-II产品含有一些刺激成分学生们必须都要在今天下午上交他们的论文像这样的飞行很快会引起注意的别松开你的鞋带她气喘吁吁地说他蹑手蹑脚的走进房间总的来说,她接受家庭生活中的种种缺陷吉姆因为不能去游泳而不开心警方将继续观察那个间谍的一举一动居然翻完了?!

He had to eat as he had never eaten before, to handle strange tools, to glance surreptitiously about learn how to accomplish each new thing, to receive the flood of impressions that was pouring in upon him being mentally annotated classified; to be conscious of a yearning for her that perturbed him in the form of a dull, aching restlessness; to feel the prod of desire to win to the walk in life whereon she trod, to have his mind ever again straying off in speculation vague plans of how to reach to her.

对她的渴望在他心里升起,那感觉以一种隐约而痛苦的不安困扰着他。他感到欲望催逼他前进,要他跻身于她的生活圈子,逼得他不断 ssbbww.Com 胡思乱想,不断 ssbbww.Com 朦胧地思考着如何接近她。而巨,在他偷偷窥视对面的诺尔曼和其他人,要想知道什么时候用什么刀叉时,心中也在研究那人的特点,同时 ssb§bww.com 不自觉地衡量8ttt8着、鉴定着——一切都是因为8 Tt t 8。

From the Warring States Period to the Qin Dynasty, the ancient myths and the ways of searching longevity indicated that the"God"concept was equal to the"immortal"which emphasized that the athanasy of the life is a"divine"nature, unlike ordinary people. In the Han Dynasty, the immortal concept undergone a subtle change, the god was becoming closer to the"human"existence. After the establishment of the Taoism, The Eastern Jin Taoist scholars Gehong established the immortal concept of Taoism,and put the"God"downgraded to longevity who practicing the longevous knowledge,and even established a"Dixian"concept. This completed the transformation process of"Shenren"to"Dixian"concept.

从战国至秦代神话的内容和古人探求长生不死的方式来看,最初&神&和&仙&的概念是一致的,强调的是神的先天不死性,体现为不同于凡人的&神人&概念,汉时的神仙思想发生了微妙变化,神仙逐渐变为接近于&人&的存在,道教创立后,东晋的道教学者葛洪把先天的&神&降格为懂得长生术的&人&,并提出了&地仙&概念,完成了&神人&向&地仙&概念的转变。

Such calibrated ages, given by CALIB versions, are close to the calendrical true ages in full play. Thus, this is beneficial to better reconstructing the regional geochronologic history since the late Late Pleistocene and such calibrated ages can be compared directly with the archaeological evidence and other absolute dating results as well.

文章经统一校正的年龄,最大限度地接近其太阳历纪年的&真实&年龄,从而有助于更加准确地重建该地区的晚更新世晚期以来的地质年代史,并可与考古纪年及其他测年方法获得的绝对年龄直接对比。

Such calibrated ages, given by CALIB versions, are close to the calendrical 'true' ages in fall play. Thus, this is beneficial to better reconstructing the regional geochronologic history since the late Late Pleistocene and such calibrated ages can be compared directly with the archaeological evidence and other absolute dating results as well.

文章经统一校正的年龄,最大限度地接近其太阳历纪年的&真实&年龄,从而有助於更加准确地重建该地区的晚更新世晚期以来的地质年代史,并可与考古纪年及其他测年方法获得的绝对年龄直接对比。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病,不管是急性淋巴性白血病或是急性骨髓性白血病,在染色体11q23部位有染色体易位的情况;这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是,单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%;并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且,这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后,而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖,遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以,白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。