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拉斯帕尔马斯

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Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞,导致细胞生长的抑制和凋亡罗伯托利,斯特凡Purgato ,苏埃洛卡默琳,拉菲尔Fronza ,梅奥尼博洛尼亚,西蒙娜Alboresi ,莫妮卡弗兰索尼,罗伯托Corradini ,斯特凡诺斯福尔扎,安德烈Faccini ,杰森先生Shohet , Rosangela Marchelli ,和安德烈Pession儿科,博洛尼亚大学,圣' Orsola -马尔皮基医院,博洛尼亚,意大利;有机部和工业大学化学帕尔马,帕尔马,意大利和3Center的细胞和基因治疗,德州儿童癌症中心, Baylor医学院,得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞,针对一个独特的序列反义DNA链的第2外显子,并与在MYCN 其氨基端为核定位信号肽。

GM assembly plants in Pontiac, Mich. and Wilmington, Del., as well as power-train plants in Livonia, Flint and Ypsilanti Township, Mich., Parma, Ohio, and Fredericksburg, Va., were just added to the list.

通用汽车公司在密歇根州庞蒂亚克和特拉华州威尔明顿的装配厂,以及在密歇根州利沃尼亚、弗林特和伊斯兰提乡,俄亥俄州帕尔马和弗吉尼亚州弗雷德里克斯堡的电力火车厂,这些都在列表之中。

Spanair Flight 5022 was packed with vacationers bound for Las Palmas in the Canary Islands, normally a three-hour flight.

西班牙航班5022上拥挤着飞往位于金丝雀岛屿的拉斯帕尔马斯的度假客,常规飞行三小时即达。

Spanair Flight 5022 was packed with vacationers bound for Las Palmas in the Canary Islands, normally a three-hour flight.

西航5022班机搭乘去往位于CANARY群岛的拉斯帕尔马斯的游客,航程约3个小时。

Spanair Flight 5022 was packed with vacationers bound for Las Palmas in the Canary Islands, normally a three-hour flight. After a 90-minute delay, the MD-82 single-aisle aircraft, with 172 passengers and crew, tried to take off about

西班牙航班5022满载去往加利那岛的拉斯帕尔马斯旅游的乘客,通常是3小时的航程。90分钟的延误以后,MD-82单通道飞机载着172名旅客和机组人员试着在下午2点45分起飞。

The 2007 Lyra Imaging Symposium Celebrates 10 Years of Insight and Leadership Earlybird Registrants Save 24150 - t the Rancho Las Palmas Resort and Spa in Rancho Mirage California To celebrate the event%26%23039%3Bs tenth anniversary the Symposium%26%23039%3Bs official theme is %26quot%3BLeading the Way: 10 Years of Imaging Industry Insight%26quot%3B To save $150 off ...

2007lyra成像研讨会庆祝十年洞察力和领导earlybird登记节省24150-笔地区Rancho拉斯帕尔马斯加州幻象牧场度假、温泉庆祝活动26%23039%3BS中十周年座谈会26%23039%3BS中正式主题是百分之零3bleading26quot方式:10年影像业界有识之士26quot百分之零三号乙拯救过::150

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。