抵抗

The peroxisome proliferator-activated receptors play an important role in adipocyte differentiation and fatty acid metabolism, activation of PPAR may induce the differentiation of adipocyte,influence the expression of genes involved in lipogenesis and fatty acid oxidation,eventually lessen ectopic fat accumulation and improve the impaired insulin signaling,so the medicine which targets to the control point of FFA metabolism would be hopeful in the treatment of a cluster of metabolic abnormalities resulted from insulin resistance.

过氧化物酶体增殖物激活受体在脂肪细胞分化、脂肪酸代谢中起重要作用，PPAR及其所调控基因的激活可促进脂肪细胞分化、减少脂质产生、增加脂肪酸氧化，从而减少脂质的异位沉积，进一步改善损伤的胰岛素信号转导通路，逆转胰岛素抵抗。针对脂肪酸合成及氧化的关键调控点的药物可能是今后治疗胰岛素抵抗引发的一系列代谢异常的新的靶点。关键词过氧化物酶体增殖物激活受体；脂肪酸代谢；胰岛素抵抗

Against that time, if ever that time come, When I shall see thee frown on my defects, When as thy love hath cast his utmost sum, Call'd to that audit by advised respects; Against that time when thou shalt strangely pass And scarcely greet me with that sun thine eye, When love, converted from the thing it was, Shall reasons find of settled gravity,-- Against that time do I ensconce me here Within the knowledge of mine own desert, And this my hand against myself uprear, To guard the lawful reasons on thy part: To leave poor me thou hast the strength of laws, Since why to love I can allege no cause.

为抵抗那一天，要是终有那一天，当我看见你对我的缺点蹙额，当你的爱已花完最后一文钱，被周详的顾虑催去清算账目；为抵抗那一天，当你像生客走过，不用那太阳--你眼睛--向我致候，当爱情，已改变了面目，要搜罗种种必须决绝的庄重的理由；为抵抗那一天我就躲在这里，在对自己的恰当评价内安身，并且高举我这只手当众宣誓，为你的种种合法的理由保证：抛弃可怜的我，你有法律保障，既然为什么爱，我无理由可讲。

Against that time, if ever that time come,When I shall see thee frown on my defects,When as thy love hath cast his utmost sum,Call'd to that audit by advised respects;Against that time when thou shalt strangely passAnd scarcely greet me with that sun thine eye,When love, converted from the thing it was,Shall reasons find of settled gravity,--Against that time do I ensconce me hereWithin the knowledge of mine own desert,And this my hand against myself uprear,To guard the lawful reasons on thy part: To leave poor me thou hast the strength of laws, Since why to love I can allege no cause.

为抵抗那一天，要是终有那一天，当我看见你对我的缺点蹙额，当你的爱已花完最后一文钱，被周详的顾虑催去清算账目；为抵抗那一天，当你像生客走过，不用那太阳--你眼睛--向我致候，当爱情，已改变了面目，要搜罗种种必须决绝的庄重的理由；为抵抗那一天我就躲在这里，在对自己的恰当评价内安身，并且高举我这只手当众宣誓，为你的种种合法的理由保证：抛弃可怜的我，你有法律保障，既然为什么爱，我无理由可讲。

Against that time When I shall see thee frown on my defects, When as thy love hath cast his utmost sum, Called to that audit by advised respects, Against that time when thou shalt strangely pass, And scarcely greet me with that sun thine eye, When love converted from the thing it was Shall reasons find of settled gravity; Against that time do I ensconce me here Within the knowledge of mine own desert, And this my hand, against my self uprear, To guard the lawful reasons on thy part, To leave poor me, thou hast the strength of laws, Since why to love, I can allege no cause.

为抵抗那一天，要是终有那一天，当我看见你对我的缺点蹙额，当你的爱已花完最后一文钱，被周详的顾虑催去清算账目；为抵抗那一天，当你像生客走过，不用那太阳——你眼睛——向我致候，当爱情，已改变了面目，要搜罗种种必须决绝的庄重的理由；为抵抗那一天我就躲在这里，在对自己的恰当评价内安身，并且高举我这只手当众宣誓，为你的种种合法的理由保证：抛弃可怜的我，你有法律保障，既然为什么爱，我无理由可讲。

Some researches show the resistin is an important incretion related to fatness,insulin resist...

有研究显示抵抗素是一种与肥胖、胰岛素抵抗和糖尿病有关的重要激素，现就抵抗素与胰岛素抵抗及2型糖尿病的关系简要综述。

Antibacterial function of body wall was conducted by the following way: microorganism was directly resisted through the change of cuticle, such as incrassation of up-cuticle protuberance and increasing length of micro-floccus in the up-cuticle dissociation surface; exudation function of large granular orthochromatic mucous cells and reticulation mucous cells in the epidermis could be enhanced when the Eisenia fetida was induced by E. coli. Moreover, the mucus that contained compound substance of mucopolysaccharide and protein could make the bactericidal function or dilute the microorganism on the surface of earthworm, which could protect earthworm from invasion of microorganism; the content of neutral mucopolysaccharide of antibacterial function could be increased according with the exudation increment of small granular proteinaceous cells in the epidermis, which could resist bacteria invading into the epidermis of earthworm.

结果表明：蚯蚓的体壁主要是通过以下途径来抗细菌的侵袭：一是通过角质层的变化(如上胶层突起的增厚、上角层游离面中微绒毛的变长等)直接抵抗微生物的入侵；二是增加表皮中大颗粒粘液细胞和网状细胞的分泌功能，分泌出大量含有粘多糖蛋白液体复合物的粘液，在蚯蚓体表对细菌进行稀释或者起到直接杀菌的作用；三是通过增加小颗粒蛋白细胞的分泌作用，在蚯蚓的表皮中分泌出更多的抵抗疾病的中性粘多糖，从而抵抗进入蚯蚓体表内的细菌。

Aim To establish an in vitro insulin resistant model of HepG2 cells and 3T3-L1 adipocyte and to screen drug in vitro.

目的 在体外建立肝胰岛素抵抗细胞模型和脂肪细胞胰岛素抵抗模型，并初步应用于中药有效成分的胰岛素抵抗活性筛选中。

the coronary heart disease exist the insulin resistance, hyperinsulinism and lipin metabolism abnormity, they are all the dangerous factor which the coronary heart disease occurs, the insulin resist and the coronary heart disease clinical symptom serious degree are related.

冠心病存在胰岛素抵抗、高胰岛素血症及脂质代谢的异常，它们都是冠心病发生的危险因素，胰岛素抵抗与冠心病临床症状的严重程度相关。关键词：冠心病；胰岛素抵抗；血脂

The results showed as:(1)Gegen decreases fasting insulin and insulin resistance index and increases insulin sensitive index of rats of insulin resistance induced by dexamethasone significantly;(2)Gegen can improve glucose tolerance of rats of insulin resistance but not to alloxan indued diabetes mice;(3)Gegen increases glucose intake of 3T3-L1 adipocytes and improves the insulin resistance of 3T3-L1 adipocytes induced by dexamethasone significantly;(4)Gegen can activate peroxisome proliferator- activated receptor gamma, make it bind to PPAR response elements;(5)Gegen can up-regulate mRNA expression of PPAR v ,aP2 and adiponectin.

结果表明：①葛根显著降低地塞米松诱导的胰岛素抵抗大鼠血清胰岛素水平和胰岛素抵抗指数，升高胰岛素敏感指数，改善大鼠的胰岛素抵抗；②葛根显著改善胰岛素抵抗大鼠的糖耐量，但对四氧嘧啶糖尿病小鼠的糖耐量没有明显的作用；③葛根显著增加胰岛素抵抗3T3-L1脂肪细胞对葡萄糖的摄取，改善地塞米松诱导的3T3-L1脂肪细胞的胰岛素抵抗；④葛根能促进HepG2肝癌细胞过氧化物酶体增殖物激活受体γ与靶基因的特异DNA序列结合，对PPARγ及其下游基因的转录具有激活作用；⑤葛根能够促进PPARγ及其下游基因脂肪酸结合蛋白(aP2)、脂联素mRNA的表达。

The structure of the utility model is that the brush holder(1) is connected with the metal connector(3)on which the stainless brush bristl(4) is moulded .The utility model has the advantages of corrosion-resistance, rust-resistance, unhairing-resistance, no loosing,long service life, clean, beautiful appearance, economy and practicability.

实用新型的结构是炭刷架(1)用(3)连接不锈的刷子bristl的金属连接器(4)被铸造实用新型有腐蚀抵抗、铁锈抵抗， unhairing抵抗，没有疏松，长的产品使用期限，干净，美好的出现、经济和可实行性的好处。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。