抗葡萄球菌的

The results show that the dispersity of emulsion is good and the average diameter of particles is about 15 nm. Its bactericidal properties to some bacteria and epiphytes are strong under daylight lamp irradiation. The killing rate to Gram negative bacterium (Staphylococcus aureus and Bacillus subtilis) is 100%, in addition, killing activity of it to Gram positive bacterium is very high. It has a clear antibacterial circle of about 20 mm in diameter toward epiphytes such as Aspergillus niger, Aspergillus flavus and Candida albicans etc.

结果表明，混晶乳液分散性好，粒径约15nm；在普通日光灯照射下，乳液对一些细菌和真菌有很好的抗菌性能：对革兰氏阳性菌（金黄葡萄球菌和枯草芽孢杆菌）的杀灭率达到100%，对革兰氏阴性菌也有很好的杀灭性能，对黑曲霉、黄曲霉和白色念珠菌等真菌产生清晰的抑菌圈，抑菌直径约20mm。

This result provides a handhold for the discovery of new antibiotics.

初步的抗菌实验结果表明，所发现的EcMetAP1抑制剂对金黄色葡萄球菌、大肠埃希菌的生长具有一定的抑制活性，这为寻找新型抗菌药物带来了希望。

In particular, these compounds are superior to the existing cephem derivatives of the onium salt type in the antibacterial activities on methicillin-resistant Staphylococcus aureus, penicillin-resistant Streptococcus pneumoniae and imipenem-resistant Pseudomonas aeruginosa, which makes them highly useful as remedies for infectious diseases caused by various pathogenic bacteria.

特别是，它具有比现有的__盐型头孢烯衍生物更高的对抗甲氧苯青霉素抗性的金黄色葡萄球菌、青霉素抗性的肺炎链球菌和亚胺培南抗性的绿脓杆菌的抗微生物活性，并因此可非常有效地作为各种病原菌衍生的传染病的治疗剂。

METHODS Qualified sputa had been collected by the clinical microbiological laboratory and cultured to identify the SAU, then evaluated its susceptibility to some commonly used antibiotics in clinic.

对近5年来病室自合格痰标本所分离到的金黄色葡萄球菌行常用抗感染药物的敏感性分析，同时研究其在当年的全部分离菌及革兰阳性杆菌中所占的比例，采用美国临床实验室标准化委员会2000版标准判断结果。

Results Bamboo Vinegar had obvious anti- bacteria and fungal actions for the trichophyton rubrum .Trichophyton actions,and canida albicans,cryptococcus neoformans,aspergillusfumigatus.

目前国内对竹醋液抗真菌作用的研究相对较多，而对抗细菌的报道较少，主要有大肠杆菌、金黄色葡萄球菌和枯草芽孢杆菌，对这三种细菌的MIC和MBC的测定结果也不一致［3，5］。

The results showed that the three disparate treated substances have no visible antibacterial effect to E. coli , but a obvious effect to Staphylococcus aureus with inhibition of about 10 bacteriostasis units; have dissimilar effects to 10 kinds of fungi among the total kinds, and have a good inhibitory effect to Cytospora.coccodesHughes with fungistasis rate above 65%. After the gel filtration and activity detection, 50mM ammonium acetate was screened out as the more suitable eluents, the crudes were separated into strikingly unlike parts with obviously different antimicrobial activity.

结果表明，大蜡螟抗菌物质对大肠杆菌没有明显的抑制作用，而对金黄葡萄球菌抑制作用明显，抑菌活性单位在10左右；对10种植物病原真菌均有不同的抑菌活性，其中对苹果树皮腐烂病菌的抑制率达到65%以上；经过凝胶过滤分离，及对分离组分的抑菌活性测定，筛选出较合适的洗脱液为50mM乙酸铵，各分离组分抑菌活性差异明显，粗提物被分成了两个差异显著的部分。

Methods:(1) Dissoluble PGN and CpG DNA were immobilized onto the surface of biotin cuvette for establishing target. Another effective tracking approach was established by immobilizing Escherichia lipid A F583 onto the surface of Non-derivatised cuvett. The biosensor technology was applied to screen anti-inflammatory TCM targeting on three key molecules.(2) The active compositions were isolated by AB-8 macroreticular resin from lycium bark. After the activities of compositions were evaluated, the most effective compositions was confirmed. In vitro, the affinities of different concentrations composition E binding with PGN, CpG DNA and lipid A were measured separately. The effect of composition E on vigor of RAW264.7 cells were tested by MTT and CCK-8, and its inhibition on TNF-α, which was released from RAW264.7 cells induced by PGN, CpG DNA and LPS, was also tested by ELISA. In vivo, murine sepsis models were made by intravenously heat-killed E.coli and heat-killed S.aureus, then protection of composition E on mice sepsis model were observed.

(1)将PGN及CpG DNA包被于生物素样品池，将lipid A包被于非衍生样品池，分别建立以PGN、CpG DNA及lipid A为靶点的技术平台，对114种抗炎中药水提物进行筛选、评价其活性物质含量，并评估出针对上述三种病原分子均具有较高结合活性的中药；(2)利用生物传感器跟踪检测技术、大孔吸附树脂分离技术，从地骨皮中定向分离与PGN、CpG DNA及lipid A均具有较高亲和力的活性组分；在体外实验中，测定不同浓度活性组分与PGN、CpG DNA及lipid A亲和力；MTT法及CCK-8法检测活性组分对RAW264.7细胞活力的影响；ELISA法检测活性组分对PGN(2μg/ml)、CpG DNA(10μg/ml)及LPS(100ng/ml)刺激小鼠RAW264.7细胞分泌TNF-α的抑制作用；在体内实验中，采用尾静脉注射致死剂量热灭活大肠杆菌和热灭活金黄色葡萄球菌，建立细菌脓毒症小鼠模型，观察活性组分对脓毒症模型小鼠的保护作用。

But there is no specific and selective antibacterial agents to kill MRSA. The last treatment option is vancomycin. However, clinical isolations of vancomycin-resistant S. aureus were reported one after another in the United States, France, Australian and this situation is more and more serious.

治疗MRSA感染的最后一道防线是万古霉素，但在美国、法国、澳大利亚相继发现了抗万古霉素的金黄色葡萄球菌，且这一趋势在日益蔓延，因此寻找一种新的控制MRSA感染的策略变得迫在眉睫。

The results of the experiments show that it can kill the colon bacillus and golden staphylococcus that attach to the seats of the automobile, the mouth of the air-conditioner,the handle of the door,steering wheel,instrument panel,the inside and the floor of the automobile as well as the shoe closet,washroom,cupboard,air-conditioner,sement,etc,in one minute.The rate of removing and killing the bacteria can be as high as 98.5%.It can also remove the sweat smell of the seats,cigarette smell and the smell of leftover effectively,so it has the functions of sterilizing,removing smell and purifying the air in the automobile.The fragrant cvan last a long period of time and you will refresh yourself and feel energetic with it.It is an environmental protecting product and has no side effects.

实验证明：本品可在1分钟内清除附着在汽车座椅、空调口、门把手、方向盘、仪表台、车内壁、底板及家庭鞋柜、洗手间、橱具、家用空调、下水道、地下室等各部位的大肠杆菌、金黄葡萄球菌等，清除率98.5%，还能有效清除汽车座椅上吸附的汗味、烟味、食物碎沫发出的异味，达到杀菌除臭抗菌作用，可净化车内空气，并长期保持防香，提神醒脑，令人精神百倍。

The results indicated that the Honeysuckle's Leaves extracts have extensive antimicrobial activities; The ethyl acetate re-extract possess the strongest antimicrobial activity; The MIC of ethyl acetate re-extract from Honeysuckle's Leaves was 0.38% against Staphylococcus aureus, which was 0.50% against Escherichia coli.

抑菌实验结果表明，金银花叶的乙醇提取物抗菌谱较广；乙醇提取物水溶液的乙酸乙酯萃取物抑菌效果最为显著；测得其对金黄色葡萄球菌和大肠杆菌的最低抑菌浓度分别为0.38%和0.50%。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。