抗菌

This result provides a handhold for the discovery of new antibiotics.

初步的抗菌实验结果表明，所发现的EcMetAP1抑制剂对金黄色葡萄球菌、大肠埃希菌的生长具有一定的抑制活性，这为寻找新型抗菌药物带来了希望。

The morphological change of Escherichia coli were observed by transmission electron microscope, and the antibacterial mechanism of Fe/Ce codoped nano-TiO2 hydrosol was discussed.

采用透射电镜对杀菌过程中的大肠杆菌菌体形态进行观测，探讨了Fe/Ce共掺杂纳米TiO2水溶胶的抗菌机理。

For its little toxicity, good antibacterial efficiency and thecharacteristic of having no or less cross hypersusceptibility, this sort of cephalosporinhas expansive application prospect.

头孢菌素由于其具有毒性小、抗菌效果好、很少或没有交叉过敏反应的特点，此类抗生素的开发前景十分广阔。

The evident disparity of high-resistance, mid-resistance and low-resistance isolates ratio was exist at different region.

不同地州分离菌株高、中、低抗菌株的比例存在明显差别。

Recent years,it is a highlight that other un-known biological function beyond the lysozyme antibiotic function.

有关溶菌酶抗菌功能以外的其它未知生物学作用，也是当前研究的热点。

So it is supposed that if the second site of cephalosporins mother nuclide is modified, the new compounds would not only retain antibacterial activity and not be discoveried.

故设想在以往已上市的头孢菌素类药物上进行2-位取代的结构修饰，以期望获得可以保持其抗菌活性的新化合物。

Journal of Antimicrobial Chemotherapy Advance Access publication 6 December 2005 OXE β-lactamases in Acinetobacter:the story so far Molecular Chemotherapy,Centre for Infectious Diseases,University of Edinburgh,The Chancellor's Buliding,49 Little France Crecent,Edinburgh,EH16 4SB,UK The emergence of carbaoenem resistance in Acinetobacter baumannii has become a global concern since these β-lactams are often the only effectine treatment lsft against many multiresistant strains.A recent debelopmenth has the discovery of a novel group of narrow-spectrum OXA β-lactamases in carbapenem-resistant strains,some of whitch have acquired the ability to hydrolyse the carbapenems.The first of these was found in a strain isolated in Edinburgh before imipenem was in usr in the hospital.Whether these carbapenemases have been acquired or are part of the genetic make-up of this species has yet to be determined.More importantly,however,they represent an important stage in the evolution of antibiotic resistance in Acinetobacter.This paper discusses the emergence of these unusual enzymes over the past decade.

抗菌化学疗法》杂志上 2005年12月6日提前存取出版在不OXEβ-lactamases：到目前为止分子化疗，中心为传染性疾病，爱丁堡大学，议长，49岁的法国Crecent少、爱丁堡、EH16 4SB，英国 carbaoenem电阻的出现在鲍曼不动杆菌已成为全球关注这些β-lactams通常是唯一effectine对抗许多multiresistant菌株治疗lsft…最近的一debelopmenth已发现的一种β-lactamases仅OXA集团在carbapenem-resistant株，其中一些已经取得了hydrolyse能力的carbapenems第一个被发现在一株孤立在爱丁堡的药物有亚胺培南在使用之前在医院这些carbapenemases是否已经或正在部分的基因构成该物种还有待确定然而更重要的是，他们代表着一种重要阶段的抗生素耐药性的演化出不本文探讨了产生这些不寻常的酶在过去的十年。

The results showed that the biological activities are closely related to the steric conformation and distribution of electrostatic potential of carboxyl group: The coplanatity between the group of C-3 position and the parent nucleus and the coplanatity between the group of C-3 position and C-4 keto group are very important for biological activities.

结果发现该类药物的抗菌活性与C 3位的空间构象和静电势分布有着紧密的联系。C-3位羧基与C-4位酮基共面性、以及它和母核共面性对抗菌活性十分重要，C-3位两个氧原子周围较强的负静电势也是影响活性的重要因素。

DVibrio parahaemolyticus: Each essential oil from the rhizome, stem, leaf and flower, as well as in ether zone and pentane zone, the antibacterial effects of all is 100% by 0.05% density of each essential oil.

4肠炎弧菌：0.05%浓度的月桃根、茎、叶及花等精油及其层析 pentane区分物及ether区分物，即有100%之抗菌效果。

Oxford cup in vitro antibacterial medicine cup showed that it had vitro inhibitory action on beta streptococcus and colibacillus with crude drug content of 0.5g/ml; it had vitro inhibitory action on staphylococcus aureus,pneumococcus, beta streptococcus and colibacillus with crude drug content of 1.0g/ml,and decreased the death rate of mice caused by staphylococcus aureus.

牛津杯法体外抗菌试验表明0.5g生药量/ml时对乙型链球菌、大肠杆菌有体外抑制作用，1.0g生药量/ml时对金黄色葡萄球菌，肺炎球菌，乙型链球菌，大肠杆菌有体外抑制作用，降低金黄色葡萄球菌引起的小鼠病死率

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失