抗纤维蛋白溶酶

Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rate and blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

抗血栓形成兔口服木耳多糖18.5mg/kg，可明显延长特异性血栓及纤维蛋白血栓的形成时间，缩短血栓长度，减轻血栓湿重和干重，减少血小板数，降低血小板粘附率和血液粘度，并可明显缩短豚鼠优球蛋白溶解时间，降低血浆纤维蛋白原含量，升高纤溶酶活性，结果表明，木耳多糖有明显的抗血栓作用。

Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rateand blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

抗血栓形成兔口服木耳多糖18.5mg/kg，可明显延长特异性血栓及纤维蛋白血栓的形成时间，缩短血栓长度，减轻血栓湿重和干重，减少血小板数，降低血小板粘附率和血液粘度，并可明显缩短豚鼠优球蛋白溶解时间，降低血浆纤维蛋白原含量，升高纤溶酶活性，结果表明，木耳多糖有明显的抗血栓作用。

We coupled the IgG of monoclonal antibody N34 specific to UK and the Fab of monoclonal antibody SZ-51 specific to the membrane protein GMP-140 of activated platelet. The bispecific antibody (N34 SZ-51) is able to bind UK and plasma-clot simutaneously. It enhanced plasma clot lysis 5 fold by HUK whereas it enhanced plasma clot lysis 38 times by LUK. UK in association with the bispecific antibody didn't decrease the concentration of fibrinogen in the assay supernatants.

利用抗体介导使纤溶酶原激活剂定向到血栓表面，可大大提高其纤溶作用，我们用双功能团试剂将抗尿激酶的单克隆抗体N34的IgG和抗活化血小板膜蛋白GMP-l40的单抗SZ-5l的Fab片段通过二硫键共价偶联，合成的双专一性抗体（N34-SZ-51）既具有血栓亲和性也具有尿激酶亲和性，从而增加了尿激酶对血栓的专一性，使高分子量尿激酶溶栓率提高了5倍，使低分子量尿激酶溶栓率提高了38倍之多，且不影响血浆中纤维蛋白原的含量。

Wenxin capsule can promote endolethial cells releasing CO and synthesing 〓, enhance activity of HO, induce angiectasis through activating guanylic cyclase and adenglate cyclate of intracellar of vessel smooth muscle cell to enhance content of intracellar cGMP and AMP. 3. Wenxin capsule can inhibit releasing of platelet activiting factor 〓 which inhibit platelet aggregation and have antithrombosis function. 4. Wenxin capsule can promote activity of t-PA, reduce activity of PAI-1, strengthen fibrinolytic function, therefore inhibit fibrin disposition. 5. Wenxin capsule can inhibit synthesis of smooth muscle cellular DNA. Its function don't kill it directly but prevent transformation from period Go to peried S. 6. Wenxin capsule is an effective prescription of anti-coronary atherosclerosis atherosis. The results of image pattern analysis tastifies that area of lipid plaque in treating group reduce 54% and 58% in contrast with that in control group. The results of light, electro- microscopy show that structure of endolethial cell and smooth muscle cell in treating group is more integral than that in control group.

其作用机制之一是由于该药具有良好的调脂降脂作用，其不仅能明显降低血清LDL-c及升高HDL-c含量，且能有效阻止TC沉积于血管壁，从而保护内皮细胞结构完整；此外，温心胶囊尚具有明显的抗氧化作用，该药不仅能明显降低血浆LPO含量，且能提高SOD活性，同时其对血红素在细胞内代谢的调节作用也参与了抗氧化过程。2 温心胶囊能明显促进内皮细胞释放CO及合成〓，提高HO活性，通过激活血管平滑肌细胞内鸟苷酸环化酶及腺苷酸环化酶引起细胞内cGMP、AMP浓度增加而引起血管舒张。3 温心胶囊能明显抑制血小板激活因子〓的释放，从而抑制血小板聚集，抗血栓形成。4 温心胶囊能明显提高t-PA活性，降低PAI-1活性，增强纤溶功能，从而抑制纤维蛋白沉积。5 温心胶囊能明显抑制平滑肌细胞DNA合成，其抑制作用不是直接杀伤抑制，而是阻止细胞由Go期向S期转化。6 温心胶囊是抗冠状动脉粥样硬化的有效制剂，图象分析结果证实，该药治疗组脂斑面积比对照组缩小了54％和58％，光电镜结果显示内皮细胞及平滑肌细胞结构较为完整。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。