抗类脂

There are 65 species of Chinese herbs with confirmed anti-HBV activityd, in which 16 probable active constituents are pointed out. They are arene, ketone derivatives, alicyclic carboxylic acid, aromatic carboxylic acid, ester, lactone, cyanide derivatives, heterocycle derivatives, carotenoids, anthraquinones, flavonoids, vegetable tannin, alkaloid, terpenoids, steroids and protein. Among them, the complexes of flavonoids, terpenoids, steroids and alkaloids are more abundant.

确定了具有抗乙肝病毒活性的中草药品种65种，其中含可能活性成分共16种，即芳烃、酮类衍生物、脂环族羧酸、芳香族羧酸、酯、内酯、氰类衍生物、杂环衍生物、类胡萝卜素、蒽醌类、黄酮类、植物鞣质、生物碱、萜类、甾类和蛋白质，而16种中以黄酮类、萜类、甾类和生物碱类成分为多。

Have keep clear of freedom radical and but block breaks what lipoid apperception closes matter to cross oxidation to react, maintain the normal function of cellular film thereby, action declines to beautiful capacitive reactance since.

水杨梅素。具有清除自由基及可阻断类脂类化合物的过氧化反应，从而维持细胞膜的正常功能，起到美容抗衰作用。

The method does not need any special instruments and is more convenient than the methods that we have mentioned. It is an efficient means for rapid diagnosis. In addition, mutiple-clone rabbit IgG is made by the lipoid A of E. coli.

另外，多克隆兔抗大肠杆菌抗体IgG由大肠杆菌的类脂A制成，具有广谱免疫原性，肠杆菌科细菌的类脂A结构基本相同，可进行交叉免疫反应。

Objective To apply bacterial endotoxin active central lipid A as target to screening antiendotoxin herb fron liquid of fortytwo herbs by biosensor technology.

目的 以细菌内毒素活性中心类脂A为靶点，应用生物传感器技术，从42种中草药水煎液中筛选拮抗内毒素作用的中药。

This product is the main ingredient of the drug salvia for the fat-soluble quinone-type diterpene of phenolic acids and water-soluble components, have cardiovascular aspects of the pharmacological effects, in recent years, studies show that water-yong Danshensu components of the lunwen114expansion of the heart Cerebro-vascular, anti-platelet aggregation, the removal of oxygen free radicals, such as the role of a quinone-type diterpene of tanshinone stronger, and water-soluble components of anti-myocardial ischemia is the main ingredient.

本品的主药丹参的有效成分为脂溶性的二萜醌类和水溶性的酚酸类成分，均具有心血管方面的药理作用，近年来研究表明水镕性成分丹参素的扩张心脑血管，抗血小板聚集，清除氧自由基等作用较二萜醌类的丹参酮更强，且水溶性成分是抗心肌缺血的主要成分。

It is abundant in many kinds of health beneficial elements. It contains the oxidation resisting flavonoid at a high level and rutin which is rich in asparagus and is an effctive anticancer element. It also provides ursolicacid, oleanonic acid and other saponins which is helpful for lipids metabolism and for strenghtening immunity, cyclic adenosine monophosphate, and Sucrose Mortierellate that is useful for preventing aging and knub.

其中具有抗氧化作用的类黄酮含量十分丰富，包括芦笋中引以为傲的芦丁这种预防癌症成分，还有熊果酸、齐墩果酮酸等能够改善脂质代谢和提高免疫力作用的皂甙类物质，环腺苷酸等能量增强物质，以及具有抗衰老和抑肿瘤作用的多糖类物质。

Based on relative literatures,this part has included five resesearch aspects as below.1 Fifteen compounds were isolated and purified by extraction,column chromatography,and their structures were determined on the basis of spectral analysis: acteoside(Ⅰ-1),isoacteoside(Ⅰ-2),crenatoside(Ⅰ-3),cistanoside F(Ⅰ-4),sinapoyl-4-O-β-D-glucoside(Ⅰ-5),adenosine(Ⅰ-6),β-siterol(Ⅰ-7),oleanic acid(Ⅰ-8), succinic acid(Ⅰ-9),caffeic acid(Ⅰ-10),protocatechuic aldehyde(Ⅰ-11),p-hydro xybenzyl alcohol(Ⅰ-12),β-daucosterol(Ⅰ-13),D-galacitol(Ⅰ-14),D-mannitol(Ⅰ-15).Ⅰ-4～15 were obtained from this plant for the first time,andⅠ-6,7,9,and 13 were isolated from Orobanche genus for the first time.2 The scavenging test of DPPH showed that most compounds have comparative antioxidant activity as L-ascorbic acid and part of them show better activity such as the O.coerulescens extract and phenylethanoid glycosides.Acteoside showed potent free radical scavenging effects with a median inhibition concentration of 25.6μg/ml.3 The anti-HBV activities of acteoside,isoacteoside and crenatoside were measured,and all of them showed suppressive activity on the expression of HBsAg and HBeAg in the HepG2.2.15 cell line.

本论文在文献调研基础上对紫花列当化学成分及生物活性进行了研究，并从免疫抗病毒角度探讨紫花列当中特征性成分类叶升麻苷的肝保护作用及其机制。1采用大孔树脂、硅胶和Sephadex LH-20等色谱技术对紫花列当进行系统的植物化学研究，从中分离得到19个化合物，利用UV和NMR等波谱手段及理化性质鉴定了其中的15个化合物，分别为类叶升麻苷(Ⅰ-1)、异类叶升麻苷(Ⅰ-2)、crenatoside(Ⅰ-3)、cistanoside F(Ⅰ-4)、sinapoyl-4-O-β-D-glucoside(Ⅰ-5)、腺苷(Ⅰ-6)、β-谷甾醇(Ⅰ-7)、齐墩果酸(Ⅰ-8)、琥珀酸(Ⅰ-9)、咖啡酸(Ⅰ-10)、原儿茶醛(Ⅰ-11)、对羟甲基苯甲酸(Ⅰ-12)、β-胡萝卜苷(Ⅰ-13)、D-半乳糖醇(Ⅰ-14)和甘露醇(Ⅰ-15除化合物Ⅰ-1、Ⅰ-2和Ⅰ-3外，其余化合物均为首次从该植物中分离得到。2)通过大孔树脂富集该药材有效部位苯乙醇总苷，并采用HPLC测得其所含特征性成分类叶升麻苷的含量可达80%以上。3DPPH自由基清除试验显示紫花列当提取物及其所含的苯乙醇苷类化合物均具有较好的抗氧化能力，其清除DPPH自由基能力接近于抗坏血酸。4采用卡介苗整体致敏、脂多糖离体攻击构建大鼠原代肝细胞免疫性损伤模型，在体外观察类叶升麻苷的保肝作用。

Results: Up to date, most of the found chemical compostition of Flos Lonicerae conclude essential oil, flavonoid, organic acid, triterpenoid and microelement; The pharmacal researches show that it can antagonize pathogenic microorganism, anticatarrhals,...

结果 ：至目前为止，已发现的化学成分主要有挥发油、黄酮类、有机酸、三萜类、无机元素等；药理研究表明金银花具有抗病原微生物、抗炎、解热、保肝、抗生育、止血、免疫调节、降血脂、中枢兴奋等作用；临床上主要用于多种感染、各种炎症、高热症、高脂血症、肿瘤放疗、化疗口干症等；金银花质量标准主要以其主要成分绿原酸为指标，检测方法多采用薄层色谱法和高效液相色谱法。

Except decreasing the level of blood lipoids,clinical trials showed that statins could reduce ischemic damage and incidence rate of brain infarction by the effect of anti-oxidation,anti-inflammation,blocking exitotoxicity,inhibiting platelet aggregation and thrombogenesis and so on.

而大量实验证明他汀类药物具有抗氧化、抗炎症、抗兴奋毒性以及抑制血小板聚集和血栓形成等降脂以外的抗缺血性脑损害作用！'，z；在稳定脆性斑块及延缓斑块进展等方面也有很重要的作用。

Biotechnology Research Institute is primarily dedicated to education and research in biotechnology including molecular bio-pharming, subviral RNA pathogens, the metabolism of lipids and lipoproteins, functions and immune suppression, cell division and DNA replication, membrane lipids, antioxidants, molecular-genetic analysis of RNA viruses, blood coagulation.

主要致力于生物技术的教学与研究，研究领域包括分子生物药物化学，亚病毒RNA病原体，脂类和脂蛋白的物质代谢，机能和免疫抑制，细胞分裂和DNA复制，膜脂，抗氧化剂，RNA病毒的分子－遗传分析，血凝固等。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。