抗碱的

Comparison of brucine and nitrogen oxides isobrucine in their anticancer and antioxidation effect.

马钱子碱与异马钱子碱氮氧化物抗肿瘤细胞生长及抗氧化损伤作用的比较。

The binding enthalpy change, the binding molar ratio and the binding equilibrium constant of harmine with hexamer are obtained.

而对d〓与潜在的抗肿瘤药物骆驼蓬碱的相互作用研究，已得到harmine与d〓结合的摩尔结合焓变，结合常数与结合摩尔比。

Picrotoxin, a specific chloride channelblocker, partly reduced the effect of propofol on epileptiformactivity, but bicuculline, a competitive -aminobutyric acidAreceptor antagonist, failed to antagonize it.

印防己毒素，一种特殊的氯离子通道阻滞剂，部分抑制异丙酚对癫痫样电活动的作用；但是，荷包牡丹碱，一种竞争性-氨基丁酸受体拮抗剂，不能拮抗它的作用。

To produce the scientific evidence for developing and manufacturing new antitumor drugs.Methods: 1 The inhibitory effect on cell growth of Hela was measured by MTT assay in treated or untreated groups (3.125, 6.25, 12.5, 25, 50μg/ml TAM and control) for three different treatment times (24h, 48h and 72h).2 Apoptosis and cell cycle were measured by FCM in four experimental groups (0, 4, 16, 40μg/ml TAM) for 48h.3 Adopting Wright and Giemse's staining to observe the morphology of Hela cells which treated with 40μg/ml TAM.4 Using invasion experiment to detect the Hela cells'invasive abilities which treated with 40μg/ml TAM.5 The protein expressional levels of P-ERK, ERK, C-myc and Cyclin D1 in Hela cells untreated or treated with 4, 16, 40μg/ml TAM for 24h were measured by Western blot.6 Expression of anti-apoptotic gene bcl-2, apoptotic gene bax and MMP-9 in Hela cells of four experimental groups (0, 4, 16, 40μg/ml TAM for 24h), were observed by revers transcription PCR.7 The protein expression of P-ERK, ERK, Bcl-2 and Bax in Hela cells treated with 40μg/ml TAM for 24h observed by laser scanning microscopes.

1采用四甲基偶氮唑蓝法检测不同浓度北豆根总碱(3.125、6.25、12.5、25、50μg/ml)处理不同时间(24、48和72小时)对Hela细胞增殖反应的抑制作用。2采用流式细胞技术(flow cytometry，FCM)检测不同浓度北豆根总碱(0、4、16、40μg/ml)作用48小时，对Hela细胞凋亡及周期变化的影响。3瑞氏-姬姆萨染色后显微镜观察北豆根总碱(0、40μg/ml)作用24小时后Hela细胞形态学变化。4采用Transwell小室法检测北豆根总碱(0、40μg/ml)作用24小时后对Hela细胞侵袭性的影响。5采用免疫印迹方法检测不同浓度北豆根总碱(0、4、16、40μg/ml)作用24小时后，Hela细胞中磷酸化ERK、ERK、C-myc、CyclinD1的表达变化。6采用逆转录-聚合酶链反应(revers transcription PCR，RT-PCR)半定量检测北豆根总碱(0、4、16、40μg/ml)作用24小时，Hela细胞抗凋亡基因bcl-2、促凋亡基因bax、基质金属蛋白酶-9(MMP-9)的表达变化。7应用激光共聚焦显微镜(laser scanning microscope，LSM)观察北豆根总碱(0、40μg/ml)作用24小时后，Hela细胞内P-ERK、ERK、Bcl-2、Bax蛋白的表达变化。

Five types of compounds were synthesized via modification of the leading compounds, Mannich bases of cyclopentanones. Among the target compounds, one type was aromatic amine derivatives of a leading compound, three were Mannich bases of a - benzylidene cyclopentanone, the fifth was a Mannich base of a - benzyl cyclopentanone.

以具有抗炎活性的环戊酮Mannich碱为先导化合物进行结构改造，设计合成了一类已知化合物的芳胺Mannich碱衍生物，三类α-苯亚甲基环戊酮Mannich碱类化合物，一类α-苄基环戊酮Mannich碱类化合物。22个目标化合物的结构经核磁共振氢谱、红外光谱和质谱检测确证。

The interfacial tension between ABEPS solution and crude oil had been investigated. It was shown that ABEPS not only displayed outstanding salt resistance, but also good hard-water endurability, furthermore ultra low interfacial tension could be achieved without alkaline but proper amount NaCl in the water-crude oil system, which proved its excellent interfacial performance and better application prospects.

本论文还通过对ABEPS水溶液与原油之间的界面张力测定，发现ABEPS不仅具有出众的耐盐性能，而且具有良好的抗钙镁性能，合适的盐浓度下，表面活性剂水溶液与胜利原油之间可以在没有外加碱的情况下形成超低界面张力，说明这类表面活性剂具有良好的界面活性和潜在的应用前景。

Conclusions1 Capsule FuYuanYuGan shows definite protective and therapeutic effect on experimental hepatic fibrosis model rat.2 Capsule FuYuanYuGan had no liver toxication.

湖北中医学院肝病专业硕士研究生毕业论文结论：1复元愈肝胶囊具有优于秋水仙碱的抗肝纤维化的作用。2复元愈肝胶囊无明显肝毒副作用。

In this study, human tongue cancer Tca8113 cells and human umbilical venular endothelial cell ECV304 are treated with CPT and the cell proliferation and apoptosis are detected in order to investigate the effect of CPT on Tca8113 and the mechanism of antiangiogenesis.

本研究以喜树碱作用于舌鳞癌细胞(Tca8113)及人脐静脉血管内皮细胞(ECV304)，检测细胞增殖及凋亡状况，以研究喜树碱对舌鳞癌细胞及血管内皮细胞的生长抑制和凋亡诱导作用，探讨喜树碱抗鳞癌的作用及可能机理，并初步探索其抗血管生成机制，为该药治疗皮肤肿瘤和银屑病奠定实验基础。

The product alkali poor performance, installation of the wet paste using high-alkali cement protective layer may result in failure, it is used in contact with wet cement paste to be used with caution.

本品抗碱性能差，湿贴安装时使用的高碱性水泥可能造成保护层失效，故用于接触水泥的湿贴使用时须谨慎。

The ipsilateral microinjection of γ aminobutyric acid of morphine hydrochloride into the nucleus tractus solitarius blocked partly the evoked bradycardiac and depressor responses without any influence on basal blood pressure and heart rate.

NTS内注射GABA受体拮抗剂荷苞牡丹碱可拮抗吗啡的上述作用，但吗啡受体拮抗剂纳络酮几乎不影响GABA对诱发压力感受性反射的阻断效应。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。