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The ferment product of strains JF and Al with a broad spectrum of antimicrobial activity, against one or more sensitive microbes, such as Staphylococcus epidermidis, Enterobacter aerogenes, Escherichia coli and Typhoid bacillus etc, were screened out using the filter paper assay, strain C6 have inhibiting effects on VSMC proliferation.

结果:从槲寄生中分离到JF、A1、G6等11株内生真菌;G6对牛主动脉平滑肌细胞增殖有抑制作用;JF、A1发酵产物具有较广语的抗菌活性,对革兰氏阳性细菌如表皮葡萄球菌,革兰氏阴性细菌如产气肠杆菌、大肠杆菌、伤寒杆菌等均具有较强的抑制作用。

ABSTRACT To study the antibacterial constituents from the fermentation broth of endophytic fungus Penicillium sp. 0935030 from mangrove plant Acrostichum aureurm. The separation procedure was guided by antibacterial bioassay. Seven compounds were isolated and purified by column chromatography, and their structures were identified as cyclo (1), cyclo (2), 1(2Furanyl)1,2ethanediol (3),(3β,4β,22β)olean12ene3,22,23triol (4), mannitol (5), uridine (6), and liquiritigenin (7) by physicochemical and spectral data.

为研究红树林植物卤蕨内生真菌Penicillium sp.0935030发酵物中的抗菌活性成分,采用活性追踪的方法,用多种色谱技术对化合物进行分离纯化,通过理化性质和光谱数据鉴定出7个化合物,分别为:环(1),环(2),1呋喃基1,2乙二醇(3),(3β,4β,22β)12烯3,22,23三羟基齐墩果烷(4),甘露醇(5),尿苷(6)和甘草素(7)。

It can be considered that all of them can enhance antifatigue function according to related rules.

根据《保健食品功能学评价程序与方法》中的有关规定,可以认为:上述几种食药两用真菌能增强机体对运动负荷的适应能力,具有抗疲劳功能。

The molecule of antibacterial peptide displays α-helical structure of amphipathicity, which can form the ion-channel to induce the death of pathogen on the protoplasmic membrane of bacterium, eumycete and parasite.

抗菌肽分子呈双亲性的α-螺旋结构可使细菌、真菌、寄生虫的质膜形成离子通道,从而导致这些病原体死亡。

A bacteriocin-like substance producing strain T12 was screened from 212 lactic acid bacteria isolated from intestine of healthy pigs by paper disk test and was identified as Lactobacillus. The supernatant of T12 exhibited strong inhibitory activity against the gram-positive bacteria, including Micrococcus lysodeikticus, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus. A strong activity was also observed against the gram–negative bacteria and some eumycete, such as Escherichia coli, Salmonella typhimurium and Fusarium graminearum.

通过滤纸片法从健康肉猪猪大肠、小肠中分离得到212株抗生物质产生菌,以杯碟法复筛,得到1株对溶壁微球菌、金黄色葡萄球菌、枯草芽孢杆菌、蜡状芽孢杆菌等革兰氏阳性菌和大肠杆菌、鼠伤寒沙门氏菌等革兰氏阴性菌以及部分真菌如禾谷镰刀霉均有强烈抑制作用的乳酸菌。

Hepialidae be Penicillium that was isolated from the natural Cordyceps fungus, the human body contains a variety of useful,Cordyceps acid which, cordycepin and CP can adjust not only the human immune system and fatigue.also have lower serum cholesterol and beta - lipoprotein role.

蝙蝠蛾拟青霉菌丝体,即从天然冬虫夏草体内分离出的真菌,含有多种对人体有益成分,其中虫草酸、虫草素及虫草多糖不仅能调节人体免疫力、抗疲劳,还具有降低血清胆固醇和β-脂蛋白作用。

Objective To isolate fungi from sea sediment and sea water samples collected from the neritic environment in Qingdao, screen their antitumor activity and study on their fermentation condition.

目的对青岛海域海水、海泥样品进行真菌选择性分离培养,并对其发酵物进行抗肿瘤活性筛选及活性菌株发酵条件的研究。

ABSTRACT OBJECTIVE:To purify the extract from pleurotus ostreatus,and study on the physicochemical properties and antitumor activity in vitro of the purified component.

目的:对糙皮侧耳真菌提取液进行纯化,并对纯化组分的理化性质及体外抗肿瘤作用进行研究。

A total of five hundred and forty-nine isolates of endophytic fungi isolated from Taxus mairei were screened for the bioactivity targeted against Pythium ultimum and Rhizoctonia solani.

从南方红豆杉中分离到549株内生真菌,以终极腐霉Pythium ultimum、立枯丝核菌Rhizoctonia solani为靶标菌进行抗菌活性的筛选。

Viscum Coloratum endophytic fungi fermentation broth has important pharmacological action such antiatherosclerotic and antimicrobial activity etc, just as Viscum coloratum possess.

槲寄生内生真菌发酵产物同槲寄生一样具有抗动脉粥样硬化作用,并且还具有明显的抑菌作用,值得进一步深入开发研究。

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