抗病毒的

A developmental focus was placed upon the intermediates of the drug such as cephalosporin,antihypertensive,antilipemic,antiulcer,antineoplastic,antiviral,antineuralgic,vitamin and amino acid.

重点发展第二、三、四代头孢菌素中间体、第三、四代喹诺酮类药物中间体、新型抗高血压药物中间体、新型抗高血脂药物中间体、抗溃疡药物中间体、抗癌药及抗病毒药物的中间体、中枢神经药物中间体、手性药物中间体、维生素及各种氨基酸。

Specific biological actiities of indole alkaloids presented here include: cytotoxicity, antiiral, antiparasitic, antiinflammatory, serotonin antagonism, Ca-releasing, calmodulin antagonism, and other pharmacological actiities.

在这里，我们展示了吲哚类生物碱的独特生物活性，包括：细胞毒、抗病毒、抗寄生虫、抗炎、拮抗5-羟色胺、钙释放、拮抗钙调蛋白及其他药理活性。

At the same time,its new bio-effects on the heart-blood vessel system,antimicrobial,immunological regulation,anti-inflammation and antivirus have been identified clinically for a long time.

近年来，大量的研究证实AT具有抗肿瘤、抗静脉机能不全、抗溃疡、促创伤愈合、抗抑郁以及恢复神经功能等多种药理活性，同时还显现出在心血管、免疫调节、抗炎、抗病毒等方面的药理作用。

Order to understand the antigenecity of human JC virus,hemagglutination inhibition and immunoblot were

结果发现人体抗JC 病毒的抗血清只能与native的JC 病毒颗粒反应因而在血球凝

Biology technique is based on appearance symptom on sweet potato or Ipomoea Setosa after they are infected to identify virus. But it need long period and is apt to be limited by season. Based on coat protein of virus, serology detects virus during peculiar immunolog...

生物学方法是依据病毒侵染后在甘薯或指示植物上的外观症状进行识别，但检测速度慢，易受季节限制；血清学技术是利用病毒外壳蛋白的抗原性，据特异性的抗体抗原免疫学反应检测病毒存在，但制备抗血清需时间长，对含量少和无蛋白外壳的病毒无法检测；分子生物学方法是以核酸为基础，通过检测病毒核酸来证实病毒的存在，该技术具有灵敏度高、特异性强、适应范围广等特点。

Biology technique is based on appearance symptom on sweet potato or Ipomoea Setosa after they are infected to identify virus. But it need long period and is apt to be limited by season. Based on coat protein of virus, serology detects virus during peculiar immunology reaction of antibody and antigen. But it can't detect virus without CP and preparing antibody need more time. The molecular biology method is based on nucleic acid to detect virus. This technique has high sensitivity, strong veracity, wide suitability etc.

生物学方法是依据病毒侵染后在甘薯或指示植物上的外观症状进行识别，但检测速度慢，易受季节限制；血清学技术是利用病毒外壳蛋白的抗原性，据特异性的抗体抗原免疫学反应检测病毒存在，但制备抗血清需时间长，对含量少和无蛋白外壳的病毒无法检测；分子生物学方法是以核酸为基础，通过检测病毒核酸来证实病毒的存在，该技术具有灵敏度高、特异性强、适应范围广等特点。

Isatin has therapeutic effects on Parkinson's disease, aging, hyperlipemia, anti-epileptic, tumor, epilepsy antibacterial, anti-virus and other biological activity.

靛红的合成、结构和药理活性研究倍受关注，已有报道证明靛红具有抗帕金森病、抗衰老、降血脂、抗癫痫、抗癌、抗菌、抗病毒等多种生物活性。

Virus removal efficiency is determined by the real time PCR and inactivation efficiency is determined by cell-based infectivity assay.Enveloped DNA virus removal and inactivation: Real time PCR indicated that method based on gold magnetic particles coupled with antiserum has shown great superiority on virus removal. Cell-based infectivity assay indicate pasteurism has shown superiority on virus inactivation.

对两种指示病毒分别进行巴氏灭毒和偶联抗血清金磁颗粒处理，实时荧光定量PCR检测核酸变化确定病毒的去除效率，同时进行病毒的细胞感染力实验确定病毒的灭活效率，结果显示：在对DNA有包膜病毒的去除能力上，金磁颗粒法明显优于普通的巴氏灭活法；在对DNA有包膜病毒灭活能力上，巴氏法明显优于金磁颗粒法。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

Koroso acid in the product has actions of lowering blood sugar, fat-reducing, tumor resisting and inflammatory resisting, crataegolic acid has actions of tumor resisting, virus resisting, and cardiovascular disease resisting.

产品中的科罗索酸具有降血糖、减肥、抗肿瘤和抗炎作用，山楂酸具有抗肿瘤、抗病毒和抗心血管疾病作用。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。