抗生素

The main researches of this dissertation are summarized as follows:1. AFM study of different effects of natural and semisyntheticβ-lactam on the cell envelope of E.coli.

主要内容归纳如下：1、基于AFM大气氛中成像，研究天然与半合成内酰胺类抗生素对大肠杆菌形态的影响。

Penicillin G Potassium First Crystal is the basic chemical raw material for the production of ?-lactam antibiotics.

青霉素钾工业盐是一种用于制造β--内酰胺类系列抗生素药品的基础化学原料药。

The discovery of penicillin so that the people of pathogenic micro-organisms from infection caused by various diseases are no longer at a loss, and thus the development of a large number of β-lactam antibiotics, for the protection of human health have made great contributions to the.

青霉素的发现使人们对由病原微生物感染而引发的各类疾病不再束手无策，并由此发展了大量的β-内酰胺类抗生素，对保护人类健康作出了巨大贡献。

To date, the mechanism of resistance to antibiotics, particularly β-Lactam class of antibiotic, is becoming exceedingly complex.

尤其对临床上使用较多的头孢菌素类、青霉素类等β-内酰胺类抗生素的耐药，已给人类健康造成巨大威胁，急需阐明其复杂的耐药机制。

Beta;-lactam antibiotics is normally obtained from fermentation, purification, chemical modification and refining process.

beta；-内酰胺类抗生素一般由微生物发酵、纯化、精制以及化学修饰等过程得到。

We also observed the interaction between outer membrane permeability rate,β-lactamase and clinical effects of 5β-lactam antibiotics.

而且，进一步观察外膜通透率及β-内酰胺酶与5种β-内酰胺类抗生素临床疗效的关系。

In Jeju, Korea and gave a lecture on Enzyme Engineering in -lactam antibiotics Industry.

杨晟赴韩国参加第6 届中－韩生命科学与生物技术研讨会，并作题为-内酰胺类抗生素工业

The method is simple and rapid, the results are accurate and reproducible, and the method could be used for analysis of arginine in βlactam antibilotic injection.

本法专属、快捷，结果准确，重现性好，可以作为部分β内酰胺类抗生素注射用制剂中添加的活性物质精氨酸的含量测定方法。

The control group received CDZ 50 mg/kg, q 12 h; The control group received other β-lactam antibiotics.

观察组抗生素首选CDZ 50 mg/kg，q 12 h；对照组选用其他β内酰胺类药物。

However clinical use of these antibiotics has been compromised by bacterial β-lactamase which hydrolyze the β-lactam moiety of resistance to them.

但细菌对这类抗生素耐药性日益发展，严重影响其疗效，已成为当前临床面临的必需解决的问题。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。