抗毒性

The objective of this investigation was to compare the pharmacodynamics of Sheng Wu Niu Huang with those of the natural calculus bovis and the artificial calculus bovis from the acute toxity, antipyretic effect, hypnotic effect, anticonvulsive effect, anti-inflammatory effect, antiviral effect and the influence on the hemorheology.

运用比较药理学方法将生物牛黄中间体与天然牛黄、人工牛黄从急性毒性试验、解热作用试验、催眠作用试验、抗惊厥作用试验、抗炎作用试验、抗病毒作用试验以及对血液流变学影响等方面进行了药效学比较研究。

Daunorubicin is a potent anti-leukemia agent. However, it also has cardiac, genic and genital toxicities.

柔红霉素是强效的抗白血病制剂，但具有心脏毒性，基因毒性和生殖器官毒性。

The mechanisms of these actions may be involved in anti-exitotoxicity of aminoglutaric acid, regulating the synthesis of nitric oxide, antioxidation, antiinflammatory, inhibiting neuron apoptosis, accelerating angiogenesis, neurogenesis, neurotrophy and others.

其作用机制可能包括抗谷氨酸兴奋毒性、调节NO的合成、抗氧化作用、抗炎作用、抗神经元凋亡、促进血管生成、促进神经元再生和神经营养作用等。

The contents are mainly divided into three parts: The first part describes mechanism and metabolism rule of natural products and its classification ; The second part is about the growth and development of plants and their mutual relationship, natural biological active substances which are produced in the course of defending plant diseases and insect damages. The third part is not only the function and principle of medicine, anticancer and antioxygen activity of different kinds of natural products such as resin ,essential oil, high molecule, grease and so on but also their application. The fourth is security problem of Plant Natural Products. Through the lessons, we can correctly understand and use the relationship between plants and environment.

其课程分为13章，内容主要分为4大部分，一是阐述植物天然产物的发生机理和代谢规律，介绍相关主要植物种类，并对天然产物进行化学分类；二是讲述植物天然产物和自身生长发育之间的关系、天然产物如何影响植物之间的相互关系、以及植物如何利用天然生物活性物质抵御病虫害的威胁；三是详细描述了各种天然产物，如植物自身生长发育过程中所产生的活性物质、植物与其它生物之间的相互关系中所产生的生物活性物质、植物毒性物质、植物药理活性物质、植物抗生物质、植物树脂、植物精油、植物高分子、植物油脂、植物抗氧化活性成分等，并阐述它们的药理活性、抗癌性、抗氧化性等对人类健康起作用的的功能和原理；四是提出了植物天然产物的安全性问题，并介绍相关案例和介绍相关法规；在此基础上还专门讲述了树脂、精油、高分子、以及油脂类等天然产物的应用。

In this issue of the Journal, Joensuu et al.(pages 809–820) report their experience with trastuzumab as adjuvant therapy for ErbB2-positive breast cancer. The antibody was administered alone as the first agent and was not given concomitantly with or after agents known to be cardiotoxic, such as anthracyclines.

这一乳腺癌治疗的进步机制有可能受曲妥珠单抗和蒽环类治疗剂量和用药时间的影响，但对消除心脏毒性的最可能解释是既没有同时使用曲妥珠单抗和蒽环类，也没有在使用蒽环类后使用曲妥珠单抗。

The antifatigue function of more than forty kinds of insect,fungi,bacteria and algae was studied and sifted first in this study by detecting swimming endurance and biochemical indexes. Then,in order to choose the better ones from the compoud additives formulas composed of L-carnitine, taurine, octacosanol,vitaminE and insectA ,a cross design experiment was done. InsectA was discovered in the first experiment that it greatly improved the antifatigue function in mice. Finally, the acute toxicities, thirty-day feeding effects and the mechanisms of No. 1 antifatigue compoud additives(No.1ACF) were studied.

本研究首先通过小鼠游泳耐力试验和血液生化指标的测定对40余种昆虫、菌藻的抗疲劳作用进行了筛选；在此基础上，应用正交设计方法对以L-肉碱、二十八醇、牛磺酸和本实验筛选出的抗疲劳功效较好的昆虫A为原料的配方进行了抗疲劳作用筛选，并对筛选出的最佳配方，即抗疲劳复方添加剂1号配方进行了小鼠急性经口毒性试验、30天喂养试验和抗疲劳作用机理研究。

This result fitted with the selection standards of the optimum mutagenic dose of the microbe chemical mutagenesis.Different...

不同毒性的小麦条锈菌生理小种对EMS的敏感性不同，且在离体培养条件下，毒性较弱小种的生活能力及抗逆能力明显强于毒性较强的小种。

The compressive strength, anti-tensile and rotation strength of the scaffolds were measured by almighty vitodynamics machine. 2、To make biologic safe test of nano-zirconia calcium phosphate scaffolds in vivo and vitro with polyethylene as a negative control and phenylic alcohol of 6.4% as positive control, include cell toxicity test, systemic acute toxic test, hemolysis test, the cytotoxicity and histocompatibility of the scaffolds were evaluated to offer valuable theoretical evidence for clinical safe application.

万能生物力学机测定骨支架的压缩强度、抗拉伸强度和旋转强度。2、以聚乙烯做阴性参照材料、6.4%苯酚溶液做阳性对照材料，对纳米氧化锆/磷酸钙骨支架进行了体内、外生物安全性试验研究，包括细胞毒性试验、全身急性毒性试验、溶血试验，评价其细胞毒性、组织相容性，为确保该材料临床应用的安全性提供有价值的理论依据。

Except decreasing the level of blood lipoids,clinical trials showed that statins could reduce ischemic damage and incidence rate of brain infarction by the effect of anti-oxidation,anti-inflammation,blocking exitotoxicity,inhibiting platelet aggregation and thrombogenesis and so on.

而大量实验证明他汀类药物具有抗氧化、抗炎症、抗兴奋毒性以及抑制血小板聚集和血栓形成等降脂以外的抗缺血性脑损害作用！'，z；在稳定脆性斑块及延缓斑块进展等方面也有很重要的作用。

Compared with the single pollution, the eco-toxicity of compound pollution of As+Cd and Cu+Cd becomes stronger, which preemie a synergistic effect, as far as the lethal concentration to the cell of duckweed's lemma is concerned; As+Cu and As+Cu+Cd is inclined to an antagonistic effect of which the eco-toxicity of compound pollution becomes weaker.

与单一污染相比，As+Cd和Cu+Cd复合污染对浮萍叶绿素毒性增强，表现为协同作用，加强了对浮萍叶细胞的伤害；而As+Cu和As+Cu+Cd复合污染对叶绿素联合毒性作用趋向于毒性减少的拮抗作用。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。