抗毒性

IDO inhibits the proliferation of eukaryotic intracellular pathogens or tumor cells by depriving them of tryptophan. IDO has been targeted for neurological disorders: it causes decrease of serotonin level in the brain resulting depression, and it causes the accumulation of neurotoxic quinolinic acid. IDO plays a key role in the suppression of T cell response and antitumor immune, it induces immune tolerance to embryo and explant.

IDO可通过降低微环境中色氨酸的浓度而达到抑制病原微生物增殖的作用； IDO与神经系统疾病也密切相关，它能降低5-羟色胺的水平而导致抑郁，也可造成脑中喹啉酸等具有神经毒性的代谢产物的累积； IDO在抑制T细胞免疫和抗肿瘤免疫、诱导母胎免疫耐受和移植物免疫耐受中均发挥重要的代谢性免疫调节作用。

Suicide genes can convert the drug into toxical metabolic product, cytokines can enhance the antineoplastic and immunologic responses, angiogenesis inhibitors can inhibit the development of new vessels, and apoptosis related factors can induce the apoptosis of tumor cells.

自杀基因能将药物转化为毒性代谢产物，细胞因子能增强抗肿瘤免疫效应，血管生成抑制因子能抑制血管生成，凋亡相关分子能诱导细胞凋亡，这些基因在前列腺癌的基础和临床研究中均表现出一定的肿瘤生长抑制作用。

CCl4 results in liver toxicity through its enzymatic conversion to reactive trichloromethyl free radicals, and taurine is thought to provide protection for liver cells through its antioxidant action.

结果四氯化碳肝毒性通过其转化为无三氯自由基和牛磺酸认为是提供保护肝细胞通过其抗氧化作用。

In addition, this system can also be used for compound optimization, as well as IC50 testing. Using this system a series of compounds are identified that are effective Trypanosoma inhibitors without toxicity to human cells. Therefore, targeting tbLeuRS may represent a new venue for the development of anti-Trypanosoma drugs.

使用这一系统筛选到了对锥虫有较好抑制作用，但对人类细胞毒性较小的一系列新型化合物，因而锥虫亮氨酰tRNA合成酶很可能成为开发有效抗锥虫药物的新靶标。

The unsoluble Zn, Ca of lung tissue may be extracted by a serious of enzymes and then changed to soluble in the progress of pneumonia.

结果提示了VC是在一定范围内通过自由基机制抗气溶胶致细胞毒性。

It is a original work in the world that using these ligands to coordinate with vanadyl cation to form complexes and the study of the structures along with the anti-diabetic properties, thus provide us opportunity to obtain vanadium drug with the properties of lowering blood sugar significantly and low toxicity, the research will benefit the large number of diabeticpatients, the economic and social benefit will be obvious.

上述配体与氧钒离子形成配合物及结构和抗糖尿病功能的研究在世界上属首创工作，使我们有望制备出具有显著降血糖功能且低毒性的钒类药物，为广大糖尿病患者带来福音，产生明显的经济效益和社会效益。

Flos Daturae combined with Semen Strychni reduced the toxicity of the latter, suggesting that this formula antagonizes the toxicity.

提示该配方对毒性有拮抗作用，为该药配方的合理性提供了实验依据。

Suicide gene therapy is a new experimental form of cancer chemotherapy that is currently being evaluated in human trials. Cytosine deaminase is an enzyme found in a variety of bacteria and fungi where is capable of deaminating cytosine to uracil.

将某些细菌及病毒中特有的药物敏感基因转导入肿瘤细胞，使肿瘤细胞产生某些酶类，将原来无毒的抗病毒药物或化疗前体药物代谢转化成细胞毒性产物而杀伤宿主细胞，这种使肿瘤细胞自杀的基因称为&自杀基因&。

This article reviewed the toxic action of cadmium to rat epididymides and its mechanism of protection or antagonism.

该文阐述了镉对大鼠附睾组织的毒性作用以及各种可能的防护、拮抗机制。

Toxicity tests showed dextran and trehalose solutions had no effects on in vitro development of morulae after exposed for 5-20 mm at 250C.

抗冻保护剂溶液对桑椹胚的毒性试验证明，25℃下，胚胎在葡聚糖和海藻糖溶液中平衡5-20分钟，对其体外发育无不良影响。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。