抗抑制

Our prophase research found that A_3 was the most effective component on the inhibition of the myometrium contraction and dysmenorrheal which was related to inhibiting PGs.

我们前期的研究发现：A_3为当归挥发油中最佳抑制子宫收缩、抗痛经活性部位，其抑制子宫收缩机制可能与抑制PGs生成有关。

It was concluded that the effects of administration of YT by ip and endermosis is contrary to that of administration by po.The Neostigmine-induced hyperperistalsis of the small intestine was inhibited and the inhibitory effect of Atropine enhanced by ip and sc administration of YT suggesting the mechanism of YT involved the antagonism of Ach. But the contraction of isolated rabbit ileum was not inhibited by YT.

对于羊蹄叶水提取物抗腹泻作用机制的研究表明，腹腔注射、皮肤给药YT可明显抑制新斯的明所致小鼠小肠推进功能亢进，也可加强阿托品抑制小鼠小肠推进运动的作用，从而表明YT的作用机制可能与Ach有关，但家兔小肠离体实验表明YT对Ach所致家兔小肠收缩无明显的抑制作用。

These changes were prevented by genistein (a protein tyrosine kinase inhibitor) and antioxidant N-acetyl-L-cysteine, but promoted by sodium orthovanadate (a protein phosphatase inhibitor), which were administered to the SD rats 20 min before ischemia.

进一步的研究表明，缺血前20 min腹腔注射给药，然后缺血30 min，发现蛋白酪氨酸激酶抑制剂染料木黄酮和抗氧化剂N-乙酰半胱氨酸能显著地抑制核内STAT3的磷酸化水平及DNA结合活性的增加(磷酸化水平从2.3和2.5倍分别降为1.2和1.4倍， DNA结合活性则从2.8和3.7倍分别降为1.1和1.5倍)，而蛋白酪氨酸磷酸酶抑制剂矾酸钠则能明显地促进他们的增高(磷酸化水平从2.0倍增到3.4倍， DNA结合活性从3.1倍增为5.1倍)。

Suicide genes can convert the drug into toxical metabolic product, cytokines can enhance the antineoplastic and immunologic responses, angiogenesis inhibitors can inhibit the development of new vessels, and apoptosis related factors can induce the apoptosis of tumor cells.

自杀基因能将药物转化为毒性代谢产物，细胞因子能增强抗肿瘤免疫效应，血管生成抑制因子能抑制血管生成，凋亡相关分子能诱导细胞凋亡，这些基因在前列腺癌的基础和临床研究中均表现出一定的肿瘤生长抑制作用。

Biological activities of SPThe inhibitory effect of SP on oxidation of lipids and the acitivity of lipoxygenase, the scavenging or quenching effect of SP on free radicals, and the influences of SP on the malonaldehyde content in mice liver juice, liver mitochondria and liver red blood cell were studied. The results showed that SP can inhibit the auto-oxidation of lard and soybean oil at 60 and can inhibit the activity of lipoxygenase significantly; SP also had scavenging effect on hydroxylradicals generated by Fenton system with IC50 value 6.220 mg/ml, under the concentration range of 1 mg/ml-50mg/ml, the scavenging rate of SP to -OH increased strongly when the concentration of SP increased, the maximum scavenging rate was 85.4%.

大豆多肽的生物活性研究研究了大豆多肽抗油脂氧化、抑制脂肪氧合酶及清除自由基的作用，以及对小鼠肝组织匀浆、肝线粒体和红细胞丙二醛含量的影响，结果显示：在60℃时，大豆多肽对猪油与豆油的自动氧化均有一定的抑制作用：对脂肪氧合酶的抑制作用显著：对Fenton体系产生的羟基自由基具有明显的清除作用，其IC_(50)值为6.220mg／ml。

The results showed that the three disparate treated substances have no visible antibacterial effect to E. coli , but a obvious effect to Staphylococcus aureus with inhibition of about 10 bacteriostasis units; have dissimilar effects to 10 kinds of fungi among the total kinds, and have a good inhibitory effect to Cytospora.coccodesHughes with fungistasis rate above 65%. After the gel filtration and activity detection, 50mM ammonium acetate was screened out as the more suitable eluents, the crudes were separated into strikingly unlike parts with obviously different antimicrobial activity.

结果表明，大蜡螟抗菌物质对大肠杆菌没有明显的抑制作用，而对金黄葡萄球菌抑制作用明显，抑菌活性单位在10左右；对10种植物病原真菌均有不同的抑菌活性，其中对苹果树皮腐烂病菌的抑制率达到65%以上；经过凝胶过滤分离，及对分离组分的抑菌活性测定，筛选出较合适的洗脱液为50mM乙酸铵，各分离组分抑菌活性差异明显，粗提物被分成了两个差异显著的部分。

The integrations between the episome DNA and the Dd2 genomic DNA at the sites of HRP3-5'and HRP2-3' were identified by the PCR analysis after 7 weeks of transformation but that of the site of Pfdyn gene was not identified.

在恶性疟原虫体外抑制实验中，纯化的抗Pfdyn-N IgG可以在体外有效地抑制恶性疟原虫Dd2和FCC1虫株的生长，抑制率分别达92.6％和91.8％。

The principles for treatment of IC are based on (1) controlling the dysfunctional epithelium by continual replenishment of the glycosaminoglycan layer,(2) inhibiting neurological hyperactivity by administration of amitriptyline or imipramine,(3) suppression of allergies with antihistamines, and (4) pain control with non-steroid anti-inflammatory drugs, Cox-2 inhibitors or tranquilizers.

基於这些可能的生成原因，对於间质性膀胱炎治疗的原则，主要是根据：一、控制功能异常之尿路上皮细胞，补充膀胱表皮之GAG层，二、经由amitriptxline或imipramine以抑制神经性活化作用，三、利用抗组织胺抑制过敏反应，四、使用NSAID、Cox-2抑制剂或是镇定剂作为疼痛控制。

For metabolites of strain SIPI-800, three active compounds were found, named as SIPI-800-1, 2 and 3 respectively, moreover SIPI-800-1 was new compound showing immunosuppressant activity and moderate anti- anaerobic activity; 2 and 3 were isoflavones with estrogenic activity, attracting activity to fungal zoospores, inhibiting alcohol dehydrogenase and aldehyde dehydrogenase I activities.

对SIPI-800菌株的代谢产物研究，分离出3个活性化合物，分别命名为：SIPI-800-1、2和3，其中1化合物为文献没有报道的新化合物，具有免疫抑制活性（1ug/ml浓度抑制NK细胞88.9%的活性）和弱的抗厌氧菌活性；2和3为异黄酮化合物，分别为Daidzein和Genisten的7甲基化衍生物，具有雌激素活性、强吸引真菌游动孢子、抑制乙醇或醛脱氢酶等活性。

MCP could inhibit the respiration of climacteric fruits such as Starking and Fuji apple and Feicheng peach in different degree, and this effect was not be able to convert by exogenous ethylene. On the contrary, the effect of 1-MCP on the non-climacteric fruit was not ascertainment: 1-MCP inhibited the respiration of strawberry stored at 20℃ during the whole storage time, while when stored at 0℃, 1-MCP didn't inhibit the strawberry respiration.

1-MCP能够不同程度的抑制跃变型果实富士、红星苹果和肥城桃的呼吸作用，而且这种作用可以不为外源乙烯所拮抗，但对非跃变型果实草莓的呼吸作用的效果则不确定：1-MCP抑制了20℃下草莓的呼吸速率，但并没有抑制0℃下贮藏草莓的呼吸作用。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。