抗抑制

There was the least amount of acidic eluates and their inhibit rate was the lowest. The initial results of invitro t...

经体外抗肿瘤试验，初步确定超滤膜过滤物具有较好地抑制肿瘤效果。

The results indicated that some metabolites of mangrove fungal endophytes were potential resources of compounds of new antitumor activities, which are worthy of further research and development.

以上研究结果表明：一些红树林内生真菌的代谢产物对hTopo Ⅰ表现出良好的抑制活性，有望从中发现潜在的抗肿瘤先导化合物。

Conclusions］There is a significant difference at protein level between untreated and ethambutol treated mc2155 cells. It suggests that the differential expression analysis of proteomes may be useful for further study on microbiostatic mechanism of ethambutol and search for new targets toward anti-TB drug development.

结论］乙胺丁醇处理前后耻垢分枝杆菌mc2155细胞的蛋白质组具有差异，这种蛋白质组的差异分析有助于进一步研究乙胺丁醇抑制分枝杆菌生长的作用机制并为寻找新的抗结核药物作用靶标奠定基础。

［Objective］To investigate the microbiostatic mechanism of ethambutol, proteomic methods were used to find differential expression proteins in Mycobacterium smegmatis mc2155 cells treated with ethambutol.

［目的］利用蛋白质组学方法，识别乙胺丁醇处理前后耻垢分枝杆菌mc2155细胞后差异表达的蛋白质，为进一步探讨乙胺丁醇抑制分枝杆菌生长的作用机制及寻找新的抗结核药物作用靶标奠定基础。

MethodsThe external carotid artery of rat was ligated to observe the effect of PAMD on cerebral blood flow、cerebral vascular resistance、blood pressure and heart rate.ResultsPAMD could increase CBF and decrease CVR,but had no effect of cardiac function.

本课题组近年研究表明，PAMD具有较好的抗脑血缺作用，可降低脑组织含水量、抑制丙二醛的产生及增强超氧化物歧化酶的活性。

RESULTS: The kwoninone has an could significantly inhibit fibro

苦参素可通过抑制成纤维细胞增殖及TGF-β1的表达而起到抗肝纤维化作用。

The extracts from gingko leaves possess lots of functions:to improve cerebrovascular circulation and protect the brain cells against lack-blood;to expand coronary artery and prevent angina myocardial infarction;to restrain blood platelet gatherings and thrombus formings ;to eliminate harmful oxidized free radicals and enhance immunity;to guard against cancer and senile etc.

银杏叶提取物具有改善脑血管循环，保护脑细胞免受缺血损害；扩张冠状动脉，防止心绞痛及心肌梗塞；抑制血小板聚集，防止血栓形成；消除有害的氧化自由基，提高免疫力；防癌抗衰老等功能，对防治冠心病、心绞痛、脑动脉硬化、老年性痴呆症、高血压等都有较好效果。

Uses natural groove guard of world of Home Zhang group calls the grape of cogongrass cliff berry division plant, gold arranges berry tea, tea of berry of king of system of appointing national minority hereditary headmen in the Yuan.

品质独特，其产品可直接开水浸泡后再饮用，迄今未发现任何毒副作用，具有消炎止咳，消减脂肪，抗衰老，治痔疮，扩张冠状血管，抑制血栓，降血脂。

Methods:(1) Dissoluble PGN and CpG DNA were immobilized onto the surface of biotin cuvette for establishing target. Another effective tracking approach was established by immobilizing Escherichia lipid A F583 onto the surface of Non-derivatised cuvett. The biosensor technology was applied to screen anti-inflammatory TCM targeting on three key molecules.(2) The active compositions were isolated by AB-8 macroreticular resin from lycium bark. After the activities of compositions were evaluated, the most effective compositions was confirmed. In vitro, the affinities of different concentrations composition E binding with PGN, CpG DNA and lipid A were measured separately. The effect of composition E on vigor of RAW264.7 cells were tested by MTT and CCK-8, and its inhibition on TNF-α, which was released from RAW264.7 cells induced by PGN, CpG DNA and LPS, was also tested by ELISA. In vivo, murine sepsis models were made by intravenously heat-killed E.coli and heat-killed S.aureus, then protection of composition E on mice sepsis model were observed.

(1)将PGN及CpG DNA包被于生物素样品池，将lipid A包被于非衍生样品池，分别建立以PGN、CpG DNA及lipid A为靶点的技术平台，对114种抗炎中药水提物进行筛选、评价其活性物质含量，并评估出针对上述三种病原分子均具有较高结合活性的中药；(2)利用生物传感器跟踪检测技术、大孔吸附树脂分离技术，从地骨皮中定向分离与PGN、CpG DNA及lipid A均具有较高亲和力的活性组分；在体外实验中，测定不同浓度活性组分与PGN、CpG DNA及lipid A亲和力；MTT法及CCK-8法检测活性组分对RAW264.7细胞活力的影响；ELISA法检测活性组分对PGN(2μg/ml)、CpG DNA(10μg/ml)及LPS(100ng/ml)刺激小鼠RAW264.7细胞分泌TNF-α的抑制作用；在体内实验中，采用尾静脉注射致死剂量热灭活大肠杆菌和热灭活金黄色葡萄球菌，建立细菌脓毒症小鼠模型，观察活性组分对脓毒症模型小鼠的保护作用。

ConclusionHQG has low acute toxicity and can significantly inhibit the growing of Eac,Heps and S180 tumor cells.

结论HQG的急性毒性小，HQG可显著抑制小鼠移植瘤Eac，Heps和S180的生长，具有明显的抗肿瘤作用。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。