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Most patients' death arise from the metastatic spread of primary tumors There is an urgent need for the finding of novel anti-tumor and anti–metastatic drugs to improve the quality of life and survival rate of patents Justicia procumbens is an herb and used to reduce fever inflammation and canker in Taiwan We've detected that 0 3 μM JA could effectively inhibit the proliferation of oral cancer cells OC-2 and HSC3 but not normal oral keratinocytes in MTS assay JA-treated OC2 underwent apoptosis as suggested by increased sub-G1 DNA contents condensed nuclear morphologh and DNA fragmentiation The migration activity of OC-2 was also significantly reduced by treatment with low concentration of JA The expression of ?

大部分的口腔癌病患死於原位癌的转移和扩散,寻找有效抗癌和抗转移的药物疗法来增进病患的生活品质和存活率,对治疗口腔癌而言非常重要。爵床草是台湾民间常用草药,常被用来消炎止热和治疗口疮、乳瘤。我们利用MTS分析,发现处以0 3 μM的JA 48小时,即可有效抑制口腔癌细胞OC-2和HSC3的增生,但不影响正常口腔上皮细胞生长。OC-2经JA处理后,其sub-G1的DNA含量增加,并可观察到DNA固缩和梯度断裂的现象,说明JA可使OC-2走向细胞凋亡。除此之外,0 3 μM的JA亦可有效降低OC-2的迁移能力。

After treating 24 hours on the gastric cancer cells with the two drugs, morphologic changes of apoptosis with chromatinmargination, karyopyknosis, karyorrhexis, apoptotic body were found by the light and electron microscope.

2通过集落形成率的测定结果表明,联合用药组与对照组相比其集落形成率和集落形成抑制率有显著差异P<0.01,说明该药对MGC一803胃癌细胞株有明显的抗增殖作用。

Keryx is developing KRX-0401, a novel, potentially first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase (PI3K)/Akt pathway, a key signaling cascade that has been shown to induce cell growth and cell transformation.

Keryx正在开发韩国证券期货交易所,0401,一种新的,潜在的先入级,口服抗肿瘤剂,抑制磷酸肌醇3激酶(PI3K)/ AKT的途径,一种关键的信号级联反应已经显示出诱导细胞生长和细胞转化。

The total flavone in antioxidant substance extracted from leaves of tartary buckwheat and its scaveninging function to OH and O(superscript - subscript 2) were determined by photometry and the inhibitory action to Lipin peroxidation and its synergy with other substances were studied by iodimetry in the experiment.

从苦荞叶中提取抗氧化性物质,用光度法测定提取物中总黄酮的含量及对羟自由基和超氧阴离子O(上标-下标 2的清除作用,并采用碘量法研究了苦荞叶提取物对脂质过氧化的抑制作用及与其他物质的协同作用。

It contains flavonol extracted from lotus which has the effect of resisting accumulation of fat and can reduce the storage of fat in under-eye puffiness, thus, this product can decompose and release lipocyte lipid, and reduce the storage of fat in under-eye puffines by suppressing adipose synthesis.

富含从荷花提取的黄酮醇,具有很强的抗脂聚积的功能,减少眼袋脂肪的贮存,从而分解和释放脂肪细胞内质的作用,通过抑制脂肪合成来减少眼袋脂肪的贮存。

It was suggested that the pharmacodynamics and therapeutic function of Qizhi complex prescription to fatty liver were: 1. Adjust lipometabolism: reducing TC and TG; 2. Decreasing fatty degeneration of liver cell; 3. Promoting the convalescence of hepatocellular function; 4. Anti-lipid peroxide: increasing the activation of peroxidase, decreasing the content of products of lipid peroxide. 5. Restraining Kupffer cell function of fatty liver rat; 6. Improving fluidity of hepatocellular microsome and mitochondria.

芪枳合剂治疗脂肪肝的效应及药效学机制为: 1、调整脂质代谢:降低血清甘油三脂和胆固醇; 2、减轻肝细胞脂肪变性; 3、促进肝细胞功能恢复,有效治疗脂肪性肝炎; 4、抗脂质过氧化:提高抗氧化酶活性、降低脂质过氧化产物含量; 5、抑制脂肪肝大鼠Kupffer细胞功能; 6、改善肝细胞微粒体、线粒体膜流动性。

Results The extracts of Livistona chinesis induced significant growth arrested in two malignant tumor cell lines which cultured in vitro.

蒲葵子提取物的各萃取部位能抑制肝癌细胞HepG2和白血病细胞HL60的增殖,有较强的体外抗肿瘤活性。

IC50 of these cells exposed to the extracts from N-butanol for 48 hours approach 7.94% and 10.72%. Conclusion The N-butanol extracts of Livistona chinesis had obvious anti-tumor activity in vitro.

蒲葵子提取物的各萃取部位能抑制肝癌细胞HepG2和白血病细胞HL60的增殖,有较强的体外抗肿瘤活性。

By determining the extract to the chicken embryo's maximum lethal concentration and hemagglutination. By different medicine liquor concentration direct action in virus, inoculate embryo determine the change of virus titer, found that all 8 compoundings have the effect of antivirus, and Mahuang is the essential component.

测定提取液对鸡胚的最大致死浓度和对红细胞的凝集作用;以药液的不同浓度直接作用于病毒,接种鸡胚检验病毒滴度的变化,观察发现8种配方都有抑制病毒的作用,其中麻黄是发挥抗病毒作用的主要成分。

Antioxidant activity of methanol and n-hexane extract were determined by the inhibition percentage of malonyl dialdehyde under low density lipoprotein peroxidation system.

山药切细冷冻乾燥后磨成细粉,以甲醇或正己烷萃取山药粉状物,所得之粗萃取物以不同浓度测其在低密度脂蛋白(low density lipoprotein,' LDL)系统之抗氧化力,即丙二醛(malonyl dialdehyde, MDA)生成抑制率。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。