抗抑制

Results Selective Serotonin Reuptake Inhibitors are the choice antidepressants in clinical use.

结果选择性5-羟色胺再摄取抑制剂在临床应用广泛，已成为抗抑郁的一线药物。

To produce the scientific evidence for developing and manufacturing new antitumor drugs.Methods: 1 The inhibitory effect on cell growth of Hela was measured by MTT assay in treated or untreated groups (3.125, 6.25, 12.5, 25, 50μg/ml TAM and control) for three different treatment times (24h, 48h and 72h).2 Apoptosis and cell cycle were measured by FCM in four experimental groups (0, 4, 16, 40μg/ml TAM) for 48h.3 Adopting Wright and Giemse's staining to observe the morphology of Hela cells which treated with 40μg/ml TAM.4 Using invasion experiment to detect the Hela cells'invasive abilities which treated with 40μg/ml TAM.5 The protein expressional levels of P-ERK, ERK, C-myc and Cyclin D1 in Hela cells untreated or treated with 4, 16, 40μg/ml TAM for 24h were measured by Western blot.6 Expression of anti-apoptotic gene bcl-2, apoptotic gene bax and MMP-9 in Hela cells of four experimental groups (0, 4, 16, 40μg/ml TAM for 24h), were observed by revers transcription PCR.7 The protein expression of P-ERK, ERK, Bcl-2 and Bax in Hela cells treated with 40μg/ml TAM for 24h observed by laser scanning microscopes.

1采用四甲基偶氮唑蓝法检测不同浓度北豆根总碱(3.125、6.25、12.5、25、50μg/ml)处理不同时间(24、48和72小时)对Hela细胞增殖反应的抑制作用。2采用流式细胞技术(flow cytometry，FCM)检测不同浓度北豆根总碱(0、4、16、40μg/ml)作用48小时，对Hela细胞凋亡及周期变化的影响。3瑞氏-姬姆萨染色后显微镜观察北豆根总碱(0、40μg/ml)作用24小时后Hela细胞形态学变化。4采用Transwell小室法检测北豆根总碱(0、40μg/ml)作用24小时后对Hela细胞侵袭性的影响。5采用免疫印迹方法检测不同浓度北豆根总碱(0、4、16、40μg/ml)作用24小时后，Hela细胞中磷酸化ERK、ERK、C-myc、CyclinD1的表达变化。6采用逆转录-聚合酶链反应(revers transcription PCR，RT-PCR)半定量检测北豆根总碱(0、4、16、40μg/ml)作用24小时，Hela细胞抗凋亡基因bcl-2、促凋亡基因bax、基质金属蛋白酶-9(MMP-9)的表达变化。7应用激光共聚焦显微镜(laser scanning microscope，LSM)观察北豆根总碱(0、40μg/ml)作用24小时后，Hela细胞内P-ERK、ERK、Bcl-2、Bax蛋白的表达变化。

the therapeutic mechanism of sab in treating hepatic fibrosis may be related to inhibiting the expressions of tgfβ1 and its receptors.

丹酚酸b盐具有明显的抗肝纤维化作用，其作用机制与抑制tgfβ1及其受体蛋白的表达有关。

A negative synergistic inhibition effect exhibited for saccharase activity when Mn(superscript 2+)-Cd(superscript 2+) co-existed, however, an antagonistic effect displayed for catalase and urease activities to different degrees.

其中，锰镉复合污染对蔗糖酶表现出协同抑制负效应的特征，对过氧化氢酶和脲酶则表现出不同程度的拮抗作用。

Objective To observe the effect of rabbit sacculus rotundus peptides on virulent Newcastle disease virus.

目的观察兔圆小囊抗菌肽对鸡新城疫病毒强毒株有无抑制作用。

Excellent physical and chemical properties and environmental quality, non-toxic, odorless, mildew, alkali resistance, Sassafras washing, 3 hours in addition to formaldehyde at the rate of more than 85% of bacteria and viruses have a certain extent, effective clean indoor air .

具有卓越的的理化性能和环保品质，无毒、无味、防霉抗腐、耐碱、耐檫洗，3小时除甲醛率在85%以上对细菌和病毒有一定的抑制作用，高效清新室内空气。

But whether the compound composed of them has suppressive effect on absence - like seizures of genetic tremor rats hasnt been reported. Furthermore, the animal models of investigating antiepileptic drugs were mostly induced by chemoconvulant or electrical stimulation. Since genetic factor is more primary in clinical epileptic patients, we used tremor rats fetched in from Japan as experimental animal models. We implanted electrodes in cortical and hippocampus of tremor rats and then recorded the electroencephalograms to observe effects of the traditional Chinese medicinal compound composed of Scolopendra, Bombyx Batryticatus, Uncaria and Arisacma Consanguineum on absence - like seizures in tremor rats.

而且以往多以化学致痫剂或电刺激等方法造模进行抗癫痫药物的研究，但在临床的癫痫患者中遗传因素占有相当大的比例，所以本实验应用了从日本引进的具有遗传性癫痫小发作的震颤大鼠作为实验动物模型，通过在震颤大鼠脑皮质和海马慢性安插电极后进行脑电图的记录，观察以蜈蚣、僵蚕、钩藤、制南星四味药为主的复方中药制剂对震颤大鼠癫痫小发作的抑制作用。

Objective To study the effect of lead and selenium on the growth and survival of primary cultured hippocampal neurons.

目的 观察铅、硒对原代培养的海马神经元生长及存活的影响，研究硒对铅的神经细胞生长抑制的拮抗作用。

The mRNA encoding for expression of GILZ was semiquantitatively detected by RT - PCR.

结论糖皮质激素可上调GILZ基因表达；GILZ的高表达可以抑制NF-κB与AP-1的活性，具有抗炎症反应的作用。

From the experiments, we can see the affect of concrete performances mixing with liter polypropylene fiber and glass fiber is minor. Compare with common concrete, the crack-load of concrete slab mixing with liter polypropylene fiber and glass fiber is marked improved. Mixing with liter polypropylene fiber and glass fiber, the behavior of cracks-resisting of is marked improved, and the cracks are controlled and smeller.

研究表明，在混凝土中掺入低掺量的聚丙烯纤维或玻璃纤维对抗压强度及抗拉强度的影响较小；纤维混凝土板比普通混凝土板的开裂荷载有较为显著的提高；加入低掺量的聚丙烯纤维后，混凝土板的抗塑性开裂性能有显著提高，可以抑制、细化裂缝。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。