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The results showed that over 500.0 μg/L of Jagged-1/Fc led to the obvious enhancement of the proportion of CD4+CD25+ T cells within the day 4 to 6 of induction, which was abrogated with an anti-Jagged-1/Fc monoclonal antibody. This induction action of Jagged-1/Fc on CD4+CD25+ T cells was also inhibited by the block of a Notch signal pathway with N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester. The level of IL-4 and IL-10 in the supernatant of T cell culture and their intracellular level were elevated by the induction of Jagged-1/Fc,and the level of TGF-β1 in the supernatant was not altered.

结果显示,超过500.0 μg/L剂量的Jagged-1/Fc使CD4+CD25+ T细胞百分比明显增高,诱导时间需要4~6天,抗Jagged-1单抗能抵消Jagged-1/Fc的诱导作用,用DAPT阻断Notch信号通路的活化也能抑制Jagged-1/Fc的诱导作用,Jagged-1/Fc诱导分化的T细胞培养上清中IL-4和IL-10的水平明显增高,TGF-β1无明显变化,胞内IL-4,IL-10,IL-2和TNF-α的水平也呈增高趋势。

Here we show that knockdown of owl monkey CypA by RNA interference correlates with suppression of anti-HIV-1 activity. However, reintroduction of CypA protein to RNAi-treated cells did not restore antiviral activity.

对这种矛盾现象所做的一项研究表明,通过RNA干涉剔除猫头鹰猴的CypA,可抑制其抗HIV-1活性,但再引入CypA蛋白却不能恢复抗病毒活性。

At the early stage of stress (2 d and 5 d), the Pn, Tr, Ci and Gs of own-root plant were significantly decreased, while Ls was significantly increased, the inhibition of photosynthesis of own-root plant was mainly caused by stomatal factor, water use efficiency was significantly elevated, resulting from lower Pn.

在NaCl胁迫下,自根苗和嫁接苗叶片和根系中酶(SOD、POD、CAT和APX)活性和抗氧化剂含量发生明显变化,或被诱导上升,或被抑制下降,但嫁接苗各指标均显著高于自根苗,而丙二醛含量显著低于自根苗,表现出较强的抗氧化能力。

The biomass production of grafted seedlings, activities of antioxidant enzymes and contents of proline and soluble protein in leaves of grafted seedlings were significantly higher than those of own-root seedlings, while O2(superscript -) production rate, contents of H2O2 and MDA in leaves of grafted seedlings were significantly lower than those of own-root seedlings under Ca(NO3)2 stress.

结果表明,Ca(NO3)2胁迫明显抑制植株生长,显著提高植株抗氧化酶活性,显著增加植株O2生成速率以及H2O2、MDA、脯氨酸和可溶性蛋白含量,但胁迫后嫁接苗的生物量显著高于自根苗,抗氧化酶活性、脯氨酸和可溶性蛋白含量均显著高于自根苗,而O2生成速率、H2O2和MDA含量则显著低于自根苗。

The results from insect bioassay with peach aphid showed that the transgenic plants of pBI121AVA-GUS and pBI121AVAc-GUS were aphid resistant, evidenced by a 60.81%~50.63 reduction in insect population density, some plants were more than 97%.

抗蚜实验表明含内含子和无内含子的AVA基因在转基因烟草中的抗蚜能力不同,转AVA和AVAc烟草对蚜虫的抑制率分别为60.81%和50.63%,有的植株高达97%。

In conclusion, our results suggest the possibility of the hammerhead ribozymes RzA and RzC to be used for the gene therapy of HBV infection.

结果指出,锤头状核酶RzA和RzC能介导细胞内抑制HBV的复制和表达,以及RzC通过抑制HepG2.2.15细胞中HBV的复制显示抗病毒感染的能力。表明锤头状核酶有可能作为HBV基因治疗的一种手段。

The PCR products were labeled with the fluorescent DNA dye SYBR green. The amount of burden or load was measured by GeneAmp 5700 Sequence Detection System. Using this method, the HIV 1 proviral burdens in PBMC of patient and in cell suspension treated with the compounds AZT, GL and WT were measured.

以病毒感染细胞和培养上清为材料,测定了三种化合物对细胞内的前病毒载量和培养上清中的病毒载量的抑制活性,并与合胞体形成抑制方法测定化合物抗病毒活性的结果进行了比较。

Biocontrol may be an alternative to avoid these problems in tobacco disease control. Ata28 strain is an antagonistic bacterium against tobacco brown spot was isolated from healthy tobacco in Chongqing.

Ata28菌株是从重庆烟区烟草健康植株上分离获得的烟草赤星病拮抗细菌,在PDA平板上可明显抑制烟草赤星病强致病力菌株Tbs3的生长,温室控病效果较好;为了进一步提高拮抗细菌Ata28菌株对烟草赤星病的防治效果,本研究采用紫外线、紫外线和氯化锂、硫酸二已酯及微波对Ata28菌株进行诱变选育,以期获得拮抗性能更强,生物学性状更好的优良菌株,为大田使用提供理论依据和实践经验。

Currently, the anti-influenza antibody is measured by the hemagglutinin- inhibition test. Although it is simple, but the result is easily influenced by the quality and species source of the red blood cells used. Antibody titer determined by HI test cannot reflect the protection titer either.

血球凝集抑制试验(hemagglutinin- inhibition test,HI test)是一至今仍普遍使用来测定抗流行性感冒病毒抗体的方法,此方法虽然快速、简便,但测定结果容易因为红血球的品质及来源而受影响,且血球凝集抑制试验所测定出的抗体效价亦不能反应真正的保护能力。

Melatonin can inhibit cell procedure death, stimulate plant growth, and enhance flowering of short-day plants and ripening of fruits.

褪黑激素在植物中有许多重要功能,如抗自由基抗氧化,促进植物生长和影响短日照植物开花,促进果实成熟以及抑制细胞程序性死亡等。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。