抗抑制

The anti-ulcer effect is possibly through prostaglandin mediated activity and/or through its anti-secretory and antioxidant properties.

抗溃疡作用可能是通过前列腺素介导的活性和/或通过其抑制胃酸分泌和抗氧化特性。

It's has been reported that lactoquinomycin and frenolicin B, analogues of kalamycin, can inhibit AKT for the pyran naphthoquinone skeleton they have. We found that although kalamycin has pyran naphthoquinone skeleton, but did not suppress AKT and its downstream signal system, then we make a sytematic analysis on the in vitro anti-tumor effect and mechanism of kalamycin.

有报道其类似物lactoquinomycin和frenolicin B是肿瘤靶点AKT抑制剂，并由此推断吡喃萘醌骨架在AKT抑制过程中发挥主要作用，我们发现虽然卡拉霉素含有吡喃萘醌骨架，但是并不抑制AKT及其下游信号系统；继而对卡拉霉素的体外抗肿瘤作用及其机理进行了系统的分析。

AIM: To study the effects of paecilomyces cicadidae total polysaccharides on the immune function and free radical scavenging of tissue, in immunosuppressed rats.

目的：观察蝉拟青霉总多糖对免疫抑制大鼠组织器官免疫功能调节和自由基代谢的影响，探讨其对免疫抑制大鼠组织器官的免疫调节和抗衰老作用。

AIM: To study the effects of paecilomyces cicadidae total polysaccharides on the immune function and free radical scavenging of tissues in immunosuppressed rats.

目的：观察蝉拟青霉总多糖对免疫抑制大鼠组织器官免疫功能调节和自由基代谢的影响，探讨其对免疫抑制大鼠组织器官的免疫调节和抗衰老作用。

Alpha motor neurons that innervate muscle fibers are located in the ventral horns of the spinal cord, and comprise the efferent limb of this reflex arc.

这是一个单突触反射通路，运动依赖感受器的反馈，间接的Ⅰa传入纤维也在后角与抑制的中间神经元突触，这就能通过依次激活与α运动神经元连接的拮抗肌来抑制主动肌的紧张。

Consequently, the EGS technology on the basis of ribonuclease P can prohibit the expression of the target gene at the level of mRNA.

因此，基于人类核糖核酸酶P的EGS技术能在mRNA水平抑制病毒及肿瘤靶基因的表达，在抗肿瘤、抗病毒等基因治疗领域具有广阔的应用前景。

Meanwhile, the antibodies of VIP enhanced the activation of lymphocytes and the expression of CD68, SYP in sacculus rotundus.

采用抗SP抗体使SP作用受到抑制后，圆小囊组织中淋巴细胞活化分子、DNES细胞表达SYP和巨噬细胞表达CD68分子的量均出现一定程度的减少；而当VIP作用受到抑制后，圆小囊组织中淋巴细胞活化分子、DNES细胞表达SYP和巨噬细胞表达CD68分子的量均出现一定程度的增多。

Yam steroid saponins and sapogenin are resulting in MCF-7 cells apoptosis by arrested the G0/G1 phase, increased the p53 protein with promoting apoptosis and decreased the AKT protein with anti-apoptosis and the BRCA-1 protein with repairing DNA. And, SPG has the excellent anti-cancer effect on MCF-7 cells may be due to induced much of the p53 protein in the early treated stage.

进一步的研究发现，山药固醇类皂及皂元抑制MCF-7乳癌细胞的功效，主要是诱发G0/G1期停滞，造成细胞凋亡；其透过的机制是经由p53促凋亡蛋白的增加，及AKT与BRCA-1等抗凋亡蛋白被抑制，达到双重细胞凋亡之抗癌效果；其中SPG处理之MCF-7肺癌细胞具早期大量诱发p53蛋白的特性，或许是SPG优异抗癌效果之原因。

During these years (1997-2000) in the research area of annonaceous acetogenins 5 natural products and a number of chiral-pure analogs of annonaceous acetogenins have been synthesized using sugars as the starting materials. Their high activity and selectivity against cell line of colon tumor and a relationship between activity and configuration have been found too. In the respect of inhibitor of sialidase two new methodologies for the synthesis of chiral-pure 3-deoxy-ulosonic acid using hetero-Diels-Alder reaction or asymmetric propargylation as the key reaction were developed. On the topic of anti-leukemia marine natural product clavulactone a synthetic method based on the free radical cyclization and starting from sugar has been developed. In other title of PKC inhibited agent sphingosine a new synthetic route with SN2' as the key reaction has also been disclosed.

项目期间（1997-2000）在番荔枝内酯方面从糖出发合成了五个天然产物和一批手性纯的类似物，它们对肠癌细胞有很高的活性和选择性，并与构型有关；在唾液酸酶抑制剂方面发展了二类全新手性纯高碳糖的合成方法－杂原子D－A反应或丙炔基不对称加成为关键的反应；抗白血病海洋天然产物群柱虫内酯方面研究了由糖出发和自由基环化反应的合成方法；对PKC 起抑制作用的鞘氨醇方面也开创了新的合成途径－由糖出发并以SN2'反应为关键反应。

Red grape wine with its resveratrol could inhibit carcinoma has the effects on preventing neuropathic diseases like senile dementia and Parkinson′s disease etc. and inhibiting proliferation of spirochaete.

红葡萄可抑制螺旋菌的增殖，有抗肿瘤作用，其中含有白藜芦醇，有抑制癌的效果，可防止老年性痴呆、泊金森氏综合症等神经性疾病。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。