抗原性

In order to reduce the human anti mouse antibody response and obtain optimal antigenicity, anti idiotype single chain which mimicking ovarian cancer antigen has been humanized.

为了降低人抗鼠抗体反应，获得满意的免疫原性，将模拟人卵巢癌抗原的抗独特型单链抗体人源化。

A simple artificial immune network algorithm, suitable for clustering problems with a small quantity of samples, is obtained by using the idiotype immune network. Further, a fuzzy immune network classification algorithm applied to sample classification learning is proposed by uniting the algorithm and fuzzy logical rules.

其次，利用抗原群及抗体群的作用关系，结合免疫记忆细胞的记忆功能，并借助于克隆选择原理、免疫网络的调节机制及约束条件处理方法，设计约束多目标优化免疫算法处理约束多目标优化问题，收敛性论证、性能测试、比较及实际应用表明此算法是有效的。

Objective: The first aim of this study was to investigate bcr-abl associated T cell receptorVαand Vβgene repertoire by analyzing the restricted usage and clonal expansion of TCRVαand Vβsubfamily T cells from the normal individual peripheral blood induced bybcr-abl peptideso The second aim was to construct the idiotype TCR Vα-PIRES-TCR Vβeukaryotic vector and investigate its expression in vitro. The data will be expected toprovided the methods in development of the leukemia antigen specific cytotoxic Tlymphocyte modified by the specific TCR.

目的：通过分析bcr-abl多肽诱导正常人T细胞克隆性增殖和TCR Vα和TCR Vβ基因选用情况，获得识别bcr-abl多肽的特异性TCR基因，并构建TCR Vα和TCR Vβ双基因表达载体及分析其体外转染细胞和表达特点，从而为研制TCR转基因获得白血病抗原特异T细胞的研究提供实验依据。

Lamblia SUCH/89/BTMRI/2(C2) variant-specific surface antigen gene to that of sequence（TSA417） published in GenBank was 99% both at the nueleotide and the amino acid levels.

该表面变异抗原基因的核苷酸序列及推导的氨基酸序列同GenBank中Gillin发表的TSA417序列的同源性均高达99％。

Objective:To study the expression and regulation of proliferating cell nuclear antigen、Ki-67、vascular endothelial growth factor、c-myc、bax and bcl-2 in three lymphadenectasis diseases,including lymphadenitis、reactive hyperplasia of lymph node、malignant lymphoma.

目的：探讨增殖细胞核抗原、Ki-67、血管内皮生长因子、c-myc、bax及bcl-2在淋巴结炎症性肿大、增生性肿大、肿瘤性肿大三大类淋巴结肿大疾病中的表达水平和规律。

The results suggest that REV viral determination is same in both the group;REV viral antigen could be detected in the bursa of Fabricius, bone marrow, and glandularis venticuli, spleen, thymus, liver, lung, kidney and heart;viruses located maily in the immature lymphotaxis and reticular cell.

REV抗原阳性细胞的分布及形态特征基本相同，阳性细胞主要是正在发育成熟的淋巴细胞和上皮性网状细胞。

Methods Four patients with chronic myeloblastic leukemia and 4 with acute myeloid leukemia received allo-BMT with graft from 1 - 3 HLA-mismatched related donors.

方法4例慢性粒细胞白血病和4例急性髓性白血病患者接受人类白细胞抗原1-3个位点不相合骨髓移植，用阿糖胞苷、环磷酰胺和全身照射或马利兰进行预处理。

Objective To study the biological and clinical characteristics in the eldly with acute myelocytic leukemia.

目的 研究老年CD7抗原阳性急性髓性白血病（CD7+AML）的临床生物学特征。

Objective To study the biological and clinical characteristics in the eldly with acute myelocytic leukemia.

王东侠，张文艺(中国中医血液医疗中心，廊坊市中医医院，河北廊坊 065000)摘要：目的研究老年CD7抗原阳性急性髓性白血病（CD7+AML）的临床生物学特征。

ABSTRACT: Objective To analyze expression of differentiation antigen of acute myeloid leukemia and its relationship with clinical characteristics and prognosis.

目的 探讨急性髓性白血病分化抗原表达与临床表现和疗效的关系。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失