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An isoantigen that on exposure to its corresponding isoantibody causes agglutination of the red blood cells to which it is attached.

同种凝集原;同族凝集原一个同种抗原,在接触它相应的同种抗体的会导致与其附在一起的红细胞发生凝集

The recipients were divided into three groups:allograft control group, allograft experimental group and isograft control group. After 60 days of transplant, vascular intimal thickness in all of the groups was observed by histological examination. The expression of PCNA and α-SMA was determined by immunohistochemistry.

动物分为3组:(1)异系移植对照组;(2)异系移植实验组;(3)同系移植对照组。60d后对移植动脉行病理组织学检测,观察移植动脉内膜增生程度,并行免疫组织化学染色检测移植动脉增殖细胞核抗原和平滑肌肌动蛋白的表达情况。

METHODS: The models of abdominal aorta transplantation were made with micro-surgery in rats. The recipients were divided into three groups: allograft control group, atorvastatin-treated group and isograft control group. Vascular intimal thickness in all of the groups was observed by histological examination. The expression of proliferation cell nuclear antigenl and α-smooth muscle actin were determined by immunohistochemistry. The content of nitric oxide was measured by nitrate reductase chromatometry.

建立大鼠腹主动脉移植慢性排斥反应模型,分为3组:异系移植对照组、异系移植治疗组和同系移植组,60d后对移植动脉行病理组织学检测,观察移植动脉内膜增生程度;并行免疫组织化学染色,检测移植动脉增殖细胞核抗原和平滑肌肌动蛋白的表达情况,行硝酸还原酶比色法测定移植动脉组织NO的含量。

aim to assess relationship between the increased lfa-1expression in intestine graft and acute rejection,and inhibitory effects of fk506on the expression of lfa-1.methods heterotopic small intestine transplantation was performed on inbred sd and wistar/a rats.the rats were randomly divided into4groups:control groups;isograft group(wistar/a→wistar/a);allograft group(sd→wistar/a);allograft plus fk506group(sd→wistar/a+fk506),

目的 探讨大鼠移植小肠组织内淋巴细胞相关抗原-1(lfa-1)的异常表达与急性排斥反应之间的关系,及fk506对其的抑制作用。方法选用近交系封闭群sd和wistar/a大鼠进行全小肠异位移植。实验分4组:非手术对照组;同基因移植组(wistar/a→wistar/a);异基因移植组(sd→wistar/a);异基因移植加用fk506治疗组[sd→wistar/a+fk506

Chromosomal translocations that juxtapose antigen receptor genes and oncogenes are frequently associated with lymphoid malignancies.

染色体易位能并置抗原受体基因和与淋巴恶性肿瘤先关的致病基因。

Fund Project: the National Natural Science and Technology Source Program, No. 2001DEA1006*Abstract: Number of neural stem cells is small. NSCs look like circle or ellipse with or without short neurite, with large nuclear-cytoplasmic ratio and deep karyotin. NSCs have no visible differences with other kinds of cells in appearance, and have no cell surface marker. Currently, there are mainly three aspects to identify NSCs: expression of specific nerve antigen, including nestin, Musashi, transcription factor, and cell adhesion molecules; self-renewal ability including single cell clone analysis, BrdU mark and S phase cell; the potential of multi-direction differentiation including immunocytochemical process and reverse transcriptase polymerase chain reaction.

由于神经干细胞的数量很少,从细胞形态来看神经干细胞为圆形或椭圆形,无或有较短的突起,核质比大,核染色较深,形态上与其它种类的细胞没有明显的差异,并且未找到一种细胞表面特异性标志物,因此目前鉴定神经干细胞主要有以下3个方面:特异性神经抗原的表达,包括巢蛋白、Musashi、转录因子及细胞黏附分子;自我更新能力,包括单细胞克隆分析、BrdU标记S期细胞;多向分化潜能,包括免疫细胞化学法、聚合酶链反应色法。

Number of neural stem cells is small. NSCs look like circle or ellipse with or without short neurite, with large nuclear-cytoplasmic ratio and deep karyotin. NSCs have no visible differences with other kinds of cells in appearance, and have cell surface marker. Currently, there are mainly three aspects to identify NSCs: expression of specific nerve antigen, including nestin, Musashi, transcription factor, and cell adhesion molecules; self-renewal ability including single cell clone analysis, BrdU mark and S phase cell; the potential of multi-direction differentiation including immunocytochemical process and reverse transcriptase polymerase chain reaction.

由于神经干细胞的数量很少,从细胞形态来看神经干细胞为圆形或椭圆形,无或有较短的突起,核质比大,核染色较深,形态上与其它种类的细胞没有明显的差异,并且未找到一种细胞表面特异性标志物,因此目前鉴定神经干细胞主要有以下3个方面:特异性神经抗原的表达,包括巢蛋白、Musashi、转录因子及细胞黏附分子;自我更新能力,包括单细胞克隆分析、BrdU标记S期细胞;多向分化潜能,包括免疫细胞化学法、聚合酶链反应色法。

The overexpression of HLA-DR and ICAM-1 is related to corneal inflammation and can promote the occurrence of keratoplasty rejection.

人类白细胞抗原DR分子和细胞间粘附分子-1的异常表达与角膜炎性反应有关,并可促进移植排斥反应的发生。

The imbalance of activating and inhibitory KIR as well as HLA-C group 1 and group 2 may be the key factor, which influences the pathogenesis of AS.

不平衡的激活和抑制基里巴斯以及人类白细胞抗原- C组1和第2组可能是关键因素,影响发病机制中的作为。

Condusion The KIR gene and HLAⅠ antigen are heredity independently and relatively stable.

KIR基因和HLA Ⅰ类抗原各自独立遗传,且相对稳定。

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