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The FLD-A11 cell could be applied without danger of tumor generation. These data found a basis for the study of specific antitumor immunity and active immunotherapy of DC-based vaccine.

本研究为FLD-A11作为肿瘤疫苗,用于特异性抗肿瘤免疫活性和主动免疫治疗的研究打下了基础。

In this paper, the ability and mechanism of antibacterial and immune defense ofChinese shrimp was studied using cytological, biochemical, molecular biological andproteomic methods. A sensitive and stable antibacterial and lysozyme assay methodswere selected. The effect of Vibrio anguillarum and laminarin (a kind of beta-1,3-glucan) on the immune ability of haemolymph of Chinese shrimp was analyzed.The changes of total haemocyte counts, antibacterial ability, lysozyme activity andlysosome membrane stability were detected.

本文采用细胞学,生物化学,分子生物学和蛋白质组学等技术,对对虾的抗菌能力和免疫防御机制进行研究,筛选了灵敏稳定的抑菌和溶菌检测方法;并对灭活鳗弧菌和海带多糖(laminarin,一种B-1, 3 葡聚糖)免疫诱导后的中国明对虾血细胞数目,血淋巴的抑菌活力,溶菌能力,溶酶体膜的稳定性进行分析;对两种重要免疫因子溶菌酶和精氨酸激酶进行克隆和表达分析。

Allabove indicated that the more antitumor ability of PELs was not theirmount,perhaps,but their quality.

以上这些说明微环境中一定水平IL-2的存在能使肿瘤的细胞免疫应答速度加快,免疫细胞获得杀伤能力所需时间短并伤百分率高,从而使在这种微环境中肿瘤细胞的生长明显受到抑制,同时也说明mIL-2〓诱导的PEL抗肿瘤能力,并非是通过免疫细胞数量上的增加来实现。

Transcription, western, and immunohistochemical analysis showed increased levels of dystrophin transcript and protein, and correct localization at the sarcolemma.

用免疫组织化学分析用纳米作为载体进行寡聚核苷酸递送的实验鼠抗肌萎缩蛋白基因RNA和抗肌萎缩蛋白的水平得到提高,而且恢复了抗肌萎缩蛋白在肌肉细胞膜上的正确位置。

Objective To screen the protective antigen of G.intestinalis and set the foundation for immune reseach of vaccine. Methods The trophozoite antigens were obtained with in vitro culture system of Giardia lamblia Stile. After further separation, purification and activity verification, the antigens were used to immunize the BALB/C mice divided into different groups,then indexes associated with immunity were determined. Through challenge infection, the most protective antigenic component of G.intestinalis were selected based on its anti-infection ability.

目的 筛选蓝氏贾第鞭毛虫的保护性抗原,免疫疫苗的研制奠定基础方法利用已建立的蓝氏贾第鞭毛虫滋养体体外培养系统,获取滋养体抗原,并进步分离、纯化、活性鉴定;然后分组免疫小鼠,检测相关免疫指标;再行攻击感染试验,视其抗感染能力,筛选出保护性强的抗原组分。

More recent evidence suggests that antimicrobial peptides are effective adjuvants, are synergistic with other immune effectors, initiate the adaptive response, support wound healing, induce or modulate of chemokine and cytokine production, alterate of gene expression in host cells, and inhibit of proinflammatory responses of host cells.

近来,越来越多的证据表明抗菌肽是有效的免疫辅助因子,能够与其他的众多免疫效应子协同作用,从而起始适应性免疫,促进伤口愈合,抑制前炎症反应以及诱导和调节细胞因子和趋化因子的产生。

MethodsEthanol was used to establish the gastric ulcer model in mouse gastral cavity. The contents of NO,NOS and ET in peripheral tissues of gastric ulcer were detected (P<0.01). ResultsThe UI of berberine-treated groups (25,50 mg/kg) was less than that of the model group.

现代医学研究表明berberine具有抗菌、止泻、抗炎、免疫抑制等多种药理作用[1];崔学军等[2]在总结berberine的药理作用及临床新用途时发现它还具有良好的保护胃黏膜、抗溃疡作用;Berberine与其它药联合使用治疗消化性溃疡的临床资料也不少,但作用机制并未阐明。

Tea polyphenols not only has the above aspects of the pharmacological effects, but also has effects of anti- saprodontia, eliminating bad breath, antibacterial, anti-virus, and cosmetic field, it is also enhance the body's comprehensive immunization ability to a certain extent, The American Medical Foundation President J.H.

茶多酚不仅具有以上几方面的药理作用,还可以抗禹齿、消除口臭、抗菌、抗病毒、美容等作用,对于增强人体的综合免疫能力也有一定的功效。美国医学基金会主席 J.H。

The thymuses, spleens, sera and anticoagulant blood were collected after the rats were killed, to carry out these works:(1) Zinc concentrations were analyzed by atomic absorption spectrophotometry;(2) Body weight and the weight of thymuses and spleens were measured, the organ index were calculated;(3) Changes in pathology of thymus and spleen were observed;(4) Using TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) method, the apoptosis of thmocytes and spleen lymphocytes was checked;(5) The expression of bcl-2、bax mRNA in thymus and spleen were detected by RT-PCR (reverse transcription polymerase chain reaction);(6) The expression of p56〓, a signal transduction protein in thymus and spleen were detected by immunohistochemistry;(7) Two-color cytofluorometric analysis was used to assess the expression of CD4, CD8, CD45RA and CD45RC in peripheral blood lymphocytes.

动物处死后留组织、抗凝血及血清,进行以下检测:(1)原子吸收法测血清锌浓度;(2)测胸腺、脾脏脏器重量并与大鼠体重比较,计算脏器指数;(3)HE染色对胸腺、脾脏进行病理观察;(4)原位末端标记法测胸腺、脾脏中淋巴细胞的自发凋亡,并通过图像分析进行比较;(5)逆转录聚合酶链式反应检测凋亡调控基因bcl-2、bax mRNA在免疫器官中的表达;(6)免疫组化方法检测信号转导蛋白p56〓在免疫器官中的表达;(7)流式细胞术分析外周血淋巴细胞中CD4+、CD8+、CD45RA+及CD45RC+CD4+、CD45RC-CD4+细胞的数量和比例。

Because the sugar cortical hormone class medicine has very strong anti-function and so on inflammation, anti-allergy, antitoxin, anti-shock, immunity suppression, thus caused it to become the basic unit medical establishment certain doctors' multi-purpose panaceas, no matter any got sick all uses, thus created the sugar cortical hormone class medicine in basic unit abusing.

由于糖皮质激素类药物具有很强的抗炎、抗过敏、抗毒素、抗休克、免疫抑制等作用,因而使其成了基层医疗机构某些医生的万能灵丹妙药,不管什么病都用上,从而造成糖皮质激素类药物在基层的滥用。

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