抗免疫的

Through all this test analyse Pathogenicity and Immunological status of ALV-J Inner Mongolia strain, the result showed the infected chickens began to have pathological change of Myelcytomatosis at 3-week: the main pathological changes of acidophile myelocyte were found in bone marrow and between cardiac muscle fibers,and there were many granules in the hyalotome.This kind of oncocyte proliferated in every tissue at different amount, but the cells that proliferated in bone marrow, cardiac muscle fiber, oarium were much more than other tissue, and they often developed neoplasma. At same condition,there were no abnormalty advent in control group, In immunological aspect: the increase of lymphokine and ANAE positive cells showed cell-mediated immunity was strengthend during antineoplastic infection; the emergence of ALV-J antibody of ELISA suggest there was humoral immunity exist at the same time.

结果显示：脾脏PCR检测结果表明1、2两实验组均有阳性病例出现，而对照组全部为阴性，说明实验鸡体内已有ALV-J内蒙株感染；接种病毒后3周龄开始出现骨髓细胞瘤病的病理变化：肝脏、脾脏有程度不同的肿大，镜下观察，骨髓内最早出现了与骨髓细胞相似、形态基本一致的大型圆形或椭圆形、胞核较大多为椭圆形、胞浆内含有大量嗜酸性圆形颗粒的髓细胞样瘤细胞增生，随后通过血流瘤细胞可转移到肝脏、心肌、卵巢或睾丸等组织并形成肿瘤性病灶，而对照组没有出现明显病变；免疫状态方面：以脾脏淋巴因子和ANAE阳性细胞增多说明细胞免疫在抗肿瘤感染过程中增强，ELISA检验实验鸡抗体出现阳性的结果表明同时也存在着体液免疫。

These pathways are essential for the vertebrate immune system to recognize and clear RNA virus with different strategies, which are integral parts of innate immune response and directly affect later-stage acquired immunity.

它们利用不同的细胞信号转导机制诱导先天性免疫反应，主要参与脊椎动物细胞识别和清除RNA病毒的原发抗感染过程，是机体先天免疫系统的一种重要反应机制，直接影响后续适应性免疫系统的作用。

Methods:To produce antihuman DR5 monoclonal antibody(mDRA6) by immunizing BALB/c mice using DR5 protein. The change of DR5 expression after DDPtreated on HL60 cells was detected by FACS. Morphologic changes of HL60 cells were observed under fluorencence microscope. Cytotoxic and apoptotic effects of mDRA6 and DDP on HL60 cells were measured by MTT analysis. DNA fragmentation was detected by agarose gel electrophoresis.

DR5蛋白免疫BALB/c小鼠，融合筛选抗DR5杂交瘤细胞，制备抗DR5单抗——mDRA6；流式细胞术测定顺铂对HL60细胞表面DR5表达及细胞凋亡率；荧光显微镜下观察mDRA6与顺铂协同作用下HL60细胞形态变化；MTT法测定不同浓度的顺铂与mDRA6对HL60细胞存活的影响；琼脂糖凝胶电泳检测mDRA6与顺铂联合对HL60细胞DNA片段化的影响。

The effect of the specific inhibitor cibacron blue of GSTs and antiparasitic drugs albendazole, praziquantel and artesunate on the activities of recombinant GSTM, GST1 and GST2 was evaluated.

研究目的解析三个胞质GSTs的基因结构及其特点，克隆三个胞质GSTs基因，鉴定原核表达的重组GSTs的免疫反应性、免疫原性、催化活性及其免疫定位和抑制剂、常用抗寄生虫药对催化活性的影响。

Calf thymosin fration 5 (THF 5), prepared by modified Goldstein method, was given to 7 patients with acute acquired immunodeficiency diseases, including 1 fulminant Japanese B encephalitis associated with respiratory failure: 1 fulminant infectious hepatitis associated with hepatic coma; 1 chronic active hepatitis associated with peritonitis; 1 systemic lupus erythematosus associated with herpes zoster: 1 severe heat-exhaustion associated with deep coma, bacteriemia, and decubitus ulcer: 1 chronic granulocy...

本组7例急性T细胞免疫功能缺陷病人，经用小牛FHF_后，临床症状及实验室检查初步说明，该制品具有一定的改善患者细胞免疫功能状态和抗病毒、霉菌感染的作用。本文所采用的小牛THF_是在Goldstein氏的提取方法基础上进行了改进，分子量在15，000以下，免疫电泳分析显示没有牛血清白蛋白的大分子物质，脐带血玫瑰花结测定存在活性。由于本组病例尚少，还有待进一步探讨。

Methods VEGF in the serum of 60 patients with RA and 28 healthy control subjects was quantified by our highly sensitive enzyme-linked immunoad sorbent assay, and its relationship to clinical and laboratory variables was analyzed . Synovial specimens were obtained from 1 RA and 1 OA patients undergoing synovectomy.

体内实验：用酶联免疫吸附方法检测了60例RA和28例健康对照血清中的VEGF值，并检测其他活动性指标及血清中特异性自身抗体：抗核周因子抗体、抗角蛋白抗体、抗环瓜氨酸肽抗体，分析它们之间的关系。

The glomeruli structure of antennal lobe is not classical. Accordingly, the mushroom body calyces have meager, and the lobes are relatively simple either. The central complex is prominent. The beetle showed notable 5-HT-like immunoreactivity throughout the whole brain, which was also strongly labelled by TPH antibody, with the pattern matching that of 5-HT. 5-HT-like positive fibers were resolved in all areas of the brain, among which the lamina and suboesophageal ganglion showed the most remarkable dark brown immunostaining.

免疫组化结果显示，异色瓢虫脑系统呈强5-HT免疫反应，表现为稳定的反应模式；其脑系统对鼠抗TPH单克隆抗体同样呈显著的免疫阳性反应，且反应模式与5-HT一致。5-HT能神经元多为切向神经元，数目相对较少，呈两侧对称分布，主要位于视叶与侧前脑之间、前脑背方及咽下神经节处，其阳性纤维呈明显的静脉曲张状，投射区域较广泛。

The central complex isprominent. The beetle showed notable 5-HT-like immunoreactivity throughout the wholebrain, which was also strongly labelled by TPH antibody, with the pattern matching that of5-HT. 5-HT-like positive fibers were resolved in all areas of the brain, among which thelamina and suboesophageal ganglion showed the most remarkable dark brownimmunostaining. While, all major neuropil regions, in general, showed low level backgroundafter TPH immunostaining for TPH mainly existing in cytoplasm. The number of 5-HT-likeimmunoreactive neurons was relatively small but possessed extensive varicose arborizations.

免疫组化结果显示，异色瓢虫脑系统呈强5-HT免疫反应，表现为稳定的反应模式；其脑系统对鼠抗TPH单克隆抗体同样呈显著的免疫阳性反应，且反应模式与5-HT一致。5-HT能神经元多为切向神经元，数目相对较少，呈两侧对称分布，主要位于视叶与侧前脑之间、前脑背方及咽下神经节处，其阳性纤维呈明显的静脉曲张状，投射区域较广泛。

Nanogold in size of 10 nm was prepared by a trisodium citrate method and used to label goat anti-human IgA to obtain an immunoresonance scattering spectral probe for IgA.

采用柠檬酸三钠改良法制备了粒径约为10 nm的纳米金，用于标记羊抗人免疫球蛋白A获得了免疫球蛋白A的免疫共振散射光谱探针。

In summary, our long-term study of Chinese medicine in treatment of aplastic anemia in clinical practice there are anti-aging, anti-fatigue, immune regulation, anti-radiation, anti-inflammatory as well as the impact of bone marrow nucleated cells, can play a good therapeutic effect, does not exclude the treatment of western medicine in the case of combined treatment of Chinese medicine, I think it is feasible and effective, and can greatly enhance the cure rate of patients with aplastic anemia and survival rate.

综上所述，我们长期研究的中医中药治疗再障，临床上确有抗衰老、抗疲劳、调节免疫、抗辐射、抗炎症以及对骨髓有核细胞的影响，能起到良好的治疗作用，在不排除西医的治疗情况下结合中医药的治疗，我认为是可行有效的，可以大大提高再障病人的治愈率与生存率。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。